Traf3ip2 - TRAF3 interacting protein 2 Gene

Mus musculus

Also known as Act1; CIKS

Gene ID: 103213 | Gene type: protein coding

About Traf3ip2

Summary

Enables signaling receptor binding activity and ubiquitin protein Ligase activity. Involved in several processes, including cell surface receptor signaling pathway; hematopoietic or lymphoid organ development; and leukocyte homeostasis. Acts upstream of or within B cell apoptotic process and humoral immune response. Is active in cytoplasmic vesicle and nucleus. Used to study Sjogren's syndrome; atopic dermatitis; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis and psoriasis 13. Orthologous to human TRAF3IP2 (TRAF3 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Traf3ip2 Products(1)

mRNA	Protein	Name
NM_134000.3	NP_598761.2	E3 ubiquitin ligase TRAF3IP2

Protein Preferred Names

Protein Names

E3 ubiquitin ligase TRAF3IP2

adapter protein CIKS

E3 ubiquitin-protein ligase CIKS	connection to IKK and SAPK/JNK
nuclear factor NF-kappa-B activator 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14971	TRAF3IP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22078	Traf3ip2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Traf3ip2	NCBI	NCBI:10758

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