OPRL1 - opioid related nociceptin receptor 1 Gene

Bos taurus

Gene ID: 100296381 | Gene type: protein coding

About OPRL1

Primary_assembly 13: 53,778,465-53,793,176 reverse strand.ARS-UCD1.2:CM008180.2

This gene has 2 transcripts (splice variants), 202 orthologues and 14 paralogues.

Summary

The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

OPRL1 Products(2)

mRNA	Protein	Name
NM_001318971.2	NP_001305900.1	nociceptin receptor isoform 1
NM_001318972.2	NP_001305901.1	nociceptin receptor isoform 1x

OPRL1 Protein Structure

7tmA_NOFQ_opioid_R

0
100
200
300
400
507 a.a.

Protein Preferred Names

Protein Names

nociceptin receptor

opiate receptor-like 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09803	OPRL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09804	Oprl1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09805	Oprl1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	OPRL1	NCBI	NCBI:4987

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