1. Gene
  2. Adh5 - alcohol dehydrogenase 5 (class III), chi polypeptide Gene

Adh5 - alcohol dehydrogenase 5 (class III), chi polypeptide Gene

Rattus norvegicus
Gene ID: 100145871 | Gene type: protein coding

About Adh5

Primary_assembly 2: 226,947,466-226,987,591 forward strand.mRatBN7.2:CM026975.1

This gene has 4 transcripts (splice variants), 404 orthologues, 17 paralogues and is associated with 7 phenotypes. Biased expression in Liver (RPKM 446.4), Kidney (RPKM 263.2) and 9 other tissues.


Enables alcohol dehydrogenase (NAD+) activity. Involved in aging and ethanol catabolic process. Located in cytoplasm and nucleus. Used to study alcohol use disorder. Biomarker of cholestasis. Human ortholog(s) of this gene implicated in AMED syndrome and asthma. Orthologous to human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Adh5 Products(1)

mRNA Protein Name
NM_001126120.1 NP_001119592.1 alcohol dehydrogenase class-3

Adh5 Protein Structure


alcohol_DH_class_III: cd08300 (5 - 372)

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  • 374 a.a.
Protein Preferred Names Protein Names

alcohol dehydrogenase class-3





S-(hydroxymethyl)glutathione dehydrogenase

alcohol dehydrogenase 2

alcohol dehydrogenase B2

alcohol dehydrogenase class-III

class III alcohol dehydrogenase, chi subunit

glutathione-dependent formaldehyde dehydrogenase

Orthologs Information

Species Symbol Source ID
Homo sapiens Adh5 NCBI NCBI:128