2. Gene
  3. SYK - spleen associated tyrosine kinase Gene

SYK - spleen associated tyrosine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100125540 | Gene type: protein coding

About SYK

Primary_assembly 14: 2,056,670-2,161,171 forward strand.Sscrofa11.1:CM000825.5

This gene has 3 transcripts (splice variants), 202 orthologues and 32 paralogues. Biased expression in spleen (RPKM 53.9), lung (RPKM 19.6) and 3 other tissues.

SYK Products(1)

mRNA Protein Name
NM_001104952.1 NP_001098422.1 tyrosine-protein kinase SYK

SYK Protein Structure

SH2_N-SH2_Zap70_Syk_like

SH2_N-SH2_Zap70_Syk_like: cd09938 (7 - 110)

SH2

SH2: cl15255 (158 - 255)

PTKc_Syk

PTKc_Syk: cd05116 (367 - 623)

  • 0
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  • 628 a.a.
Protein Preferred Names Protein Names

tyrosine-protein kinase SYK

protein-tyrosine kinase

spleen tyrosine kinase

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13038A Fostamatinib Inhibitor 99.50% Yes
HY-13038 Fostamatinib Disodium Inhibitor 99.88% Yes
HY-13038B Fostamatinib disodium hexahydrate Inhibitor 99.73% Yes
Clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Phase
HY-15968 Entospletinib Inhibitor 99.88% Phase 3
HY-15999 Cerdulatinib Inhibitor 98.96% Phase 3
HY-15999A Cerdulatinib hydrochloride Inhibitor 99.89% Phase 3
HY-15323 PRT062607 Hydrochloride Inhibitor 98.68% Phase 2
HY-109091 Lanraplenib Inhibitor 99.12% Phase 2
HY-100867A Mivavotinib monohydrochloride Inhibitor 99.91% Phase 2
HY-103018 Gusacitinib Inhibitor 99.41% Phase 2
HY-109082 Cevidoplenib Inhibitor 98.08% Phase 2
HY-109091B Lanraplenib succinate Inhibitor 98.58% Phase 2
HY-15322 PRT062607 Inhibitor / Phase 2
HY-100867 Mivavotinib Inhibitor / Phase 2
HY-109091A Lanraplenib monosuccinate Inhibitor / Phase 2
HY-13518 Piceatannol Inhibitor 98.90% Phase 1
HY-112809 GSK2646264 Inhibitor 98.39% Phase 1
Pre-clinical Phase
Bioactive Molecules (39)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12067 R406 Inhibitor 98.72% Unkown
HY-11108 R406 free base Inhibitor 99.80% Unkown
HY-14985 BAY 61-3606 dihydrochloride Inhibitor 99.91% Unkown
HY-112390A Syk Inhibitor II Inhibitor 98.05% Unkown
HY-12974 PRT-060318 Inhibitor 99.36% Unkown
HY-78263 MNS Inhibitor 99.55% Unkown
HY-145598 Sovleplenib Inhibitor 99.56% Unkown
HY-16902 RO9021 Inhibitor 98.76% Unkown
HY-16420 R112 Inhibitor 99.71% Unkown
HY-12736A GSK143 dihydrochloride Inhibitor 99.73% Unkown
HY-136198 SRX3207 Inhibitor 98.50% Unkown
HY-131341 Syk-IN-4 Inhibitor ≥98.0% Unkown
HY-12657 Syk-IN-1 Inhibitor 99.18% Unkown
HY-109082A Cevidoplenib dimesylate Inhibitor 98.48% Unkown
HY-151634 Syk-IN-6 Inhibitor / Unkown
HY-138961 ER-27319 Inhibitor 98.66% Unkown
HY-108489 ER-27319 maleate Inhibitor ≥99.4% Unkown
HY-10230S Midostaurin-d5 Inhibitor ≥98.0% Unkown
HY-112386 OXSI-2 Inhibitor / Unkown
HY-76474 BAY 61-3606 Inhibitor 98.21% Unkown
HY-130680 Syk-IN-3 Inhibitor / Unkown
HY-103018A Gusacitinib hydrochloride Inhibitor / Unkown
HY-15324 PRT062607 acetate Inhibitor 99.83% Unkown
HY-15324 PRT062607 acetate Inhibitor 99.83% Unkown
HY-P2504 Syk Kinase Peptide Substrate, Biotin labeled / Unkown
HY-112319 MK-8457 Inhibitor / Unkown
HY-N3702 Dehydroabietinol Inhibitor / Unkown
HY-12736 GSK143 Inhibitor / Unkown
HY-P2505 Syk Kinase Peptide Substrate / Unkown
HY-112390 Syk Inhibitor II dihydrochloride Inhibitor / Unkown
HY-120214 TAS05567 Inhibitor / Unkown
HY-155513 Syk-IN-8 Inhibitor / Unkown
HY-112390B Syk Inhibitor II dihydrochloride dihydrate Inhibitor / Unkown
HY-145029 SYK/JAK-IN-1 Inhibitor / Unkown
HY-149895 Syk-IN-7 Inhibitor / Unkown
HY-162427 NMS-0963 Inhibitor / Unkown
HY-160930 TOP1288 Inhibitor / Unkown
HY-112390C Syk Inhibitor II hydrochloride Inhibitor / Unkown
HY-N7314 Asebogenin Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SYK NCBI NCBI:6850