2. Gene
  3. ZGLP1 - zinc finger GATA like protein 1 Gene

ZGLP1 - zinc finger GATA like protein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GLP1; GLP-1; GATAD3

Gene ID: 100125288 | Gene type: protein coding

About ZGLP1

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:10,304,803-10,309,557 (from NCBI)

This gene has 3 transcripts (splice variants), 157 orthologues and 7 paralogues. Ubiquitous expression in testis (RPKM 1.4), spleen (RPKM 0.9) and 25 other tissues.

Summary

ZGLP1 encodes an evolutionary conserved transcriptional regulator with GATA-like zinc fingers. In females, it is expressed in embryonic germ cells and is essential for oogenic fate determination. It acts downstream of bone morphogenetic protein (BMP) and is involved in the regulation of genes involved in RNA processing, transcription and chromatin modification, retrotransposon regulation, meiotic cell cycle, and oocyte development. In males it is not required for the germ cell sex determination but is required by the spermatogonia for efficiently completing the meiotic prophase. [provided by RefSeq, Jul 2022]

ZGLP1 Products(2)

mRNA Protein Name
NM_001103167.1 NP_001096637.1 GATA-type zinc finger protein 1 isoform 1
NM_001409033.1 NP_001395962.1 GATA-type zinc finger protein 1 isoform 2

ZGLP1 Protein Structure

GATA

GATA: GATA zinc finger (206 - 240)

  • 0
  • 100
  • 200
  • 271 a.a.
Protein Preferred Names Protein Names

GATA-type zinc finger protein 1

GATA zinc finger domain containing 3

Related Diseases

Diseases Alias
Hermaphroditism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16065 ZGLP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZGLP1 MGD MGI:3696042
Canis familiaris ZGLP1 VGNC VGNC:48630
Rattus norvegicus ZGLP1 RGD RGD:2322460
Felis catus ZGLP1 VGNC VGNC:80760
Bos taurus ZGLP1 VGNC VGNC:37181