FAP targeting peptide for FXX489

Cat. No.: HY-P10945 Purity: 99.49%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

FAP targeting peptide for FXX489 is the polypeptide part of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

FAP targeting peptide for FXX489 Chemical Structure

CAS No. : 3076328-74-7

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

FAP targeting peptide for FXX489 is the polypeptide part of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand^[1].

IC₅₀ & Target^[1]

RDC Peptide

Molecular Weight

1346.53

Formula

C₆₇H₉₁N₁₅O₁₅

CAS No.

3076328-74-7

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (74.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.7426 mL	3.7132 mL	7.4265 mL
5 mM	0.1485 mL	0.7426 mL	1.4853 mL
10 mM	0.0743 mL	0.3713 mL	0.7426 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.49%

Select Batch:

Data Sheet (279 KB) SDS (252 KB)

COA (263 KB) LCMS (97 KB) Elemental Analysis Report (121 KB)

Handling Instructions (2659 KB)

References

[1]. Ravit Geva, et al. Abstract CT112: Phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of FXX489 ([177Lu]Lu-NNS309) in patients with pancreatic, lung, breast and colorectal cancers. Cancer Res (2025) 85 (8_Supplement_2): CT112.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.7426 mL	3.7132 mL	7.4265 mL	18.5662 mL
	5 mM	0.1485 mL	0.7426 mL	1.4853 mL	3.7132 mL
	10 mM	0.0743 mL	0.3713 mL	0.7426 mL	1.8566 mL
	15 mM	0.0495 mL	0.2475 mL	0.4951 mL	1.2377 mL
	20 mM	0.0371 mL	0.1857 mL	0.3713 mL	0.9283 mL
	25 mM	0.0297 mL	0.1485 mL	0.2971 mL	0.7426 mL
	30 mM	0.0248 mL	0.1238 mL	0.2475 mL	0.6189 mL
	40 mM	0.0186 mL	0.0928 mL	0.1857 mL	0.4642 mL
	50 mM	0.0149 mL	0.0743 mL	0.1485 mL	0.3713 mL
	60 mM	0.0124 mL	0.0619 mL	0.1238 mL	0.3094 mL