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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9804):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W009162S5
    Cytidine 5′-monophosphate-13C9,15N3 dilithium
    99.80%
    Cytidine 5′-monophosphate-13C9,15N3 (5'-Cytidylic acid-13C9,15N3 dilithium; 5'-CMP-13C9,15N3) dilithium is 13C and 15N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5′-monophosphate-<sup>13</sup>C<sub>9</sub>,<sup>15</sup>N<sub>3</sub> dilithium
  • HY-109015S
    Tucidinostat-d4
    98.63%
    Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively.
    Tucidinostat-d<sub>4</sub>
  • HY-125527S
    Resolvin D1-d5
    99.2%
    Resolvin D1-d5 is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages.
    Resolvin D1-d<sub>5</sub>
  • HY-W016812S
    Orotic acid-15N2 hydrate
    99.94%
    Orotic acid-15N2 is the 15N hydrate labeled Orotic acid hydrate. Orotic acid hydrate is an endogenous metabolite.
    Orotic acid-<sup>15</sup>N<sub>2</sub> hydrate
  • HY-W067028S
    Semicarbazide-13C,15N2 hydrochloride
    99.86%
    Semicarbazide-13C,15N2 hydrochloride is 15N and 13C labeled Semicarbazide.
    Semicarbazide-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub> hydrochloride
  • HY-B1455S1
    Clindamycin-13C,d3
    ≥99.0%
    Clindamycin-13C,d3 is the 13C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria.
    Clindamycin-<sup>13</sup>C,d<sub>3</sub>
  • HY-W393970S3
    2′-Deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium
    99.8%
    2′-Deoxyguanosine 5′-monophosphate-13C10,15N5 (5'-Deoxyguanylic acid-13C10,15N5) dilithium is 13C and 15N-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
    2′-Deoxyguanosine 5′-monophosphate-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub> dilithium
  • HY-N8016S
    Nonanal-d18
    Nonanal-d18 is the deuterium labeled Nonanal. Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity.
    Nonanal-d<sub>18</sub>
  • HY-146906S
    C18 Glucosyl(ß) ceramide-d5
    C18 Glucosyl(ß) ceramide-d5 is deuterium labeled C18 Glucosyl(ß) ceramide.
    C18 Glucosyl(ß) ceramide-d<sub>5</sub>
  • HY-W742012
    Clencyclohexerol-d10
    99.46%
    Clencyclohexerol-d10 is the deuterium-labeled Clencyclohexerol (HY-117406). Clencyclohexerol-d10 is a β-agonist. Clencyclohexerol-d10 can be used as a growth promoter in animals.
    Clencyclohexerol-d<sub>10</sub>
  • HY-W017387S2
    Sodium α-ketoisocaproic acid-13C6
    99.3%
    Sodium α-ketoisocaproic acid-13C6 is the 13C labeled Sodium α-ketoisocaproic acid.
    Sodium α-ketoisocaproic acid-<sup>13</sup>C<sub>6</sub>
  • HY-B0673S1
    Deupirfenidone-d3
    99.60%
    Deupirfenidone-d3 is the deuterium labeled Pirfenidone (HY-B0673). Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities.
    Deupirfenidone-d<sub>3</sub>
  • HY-14648S5
    Dexamethasone-d3-1
    98.02%
    Dexamethasone-d3-1 (Hexadecadrol-d3-1; Prednisolone F-d3-1) is a deuterium labeled Dexamethasone (HY-14648). Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
    Dexamethasone-d<sub>3</sub>-1
  • HY-15592S1
    Cabotegravir-d5
    99.31%
    Cabotegravir-d5 is deuterium labeled Cabotegravir.
    Cabotegravir-d<sub>5</sub>
  • HY-W127498S
    Epicoprostanol-d5
    Epicoprostanol-d5 is the deuterium labeled Epicoprostanol. Epicoprostanol is the compound found in adipocere.
    Epicoprostanol-d<sub>5</sub>
  • HY-114277BS
    Sotorasib-d7 isomer
    Sotorasib-d7 isomer (AMG-510-d7 isomer) is the deuterium labeled Sotorasib isomer.
    Sotorasib-d<sub>7</sub> isomer
  • HY-146836S
    (Rac)-16:0 PI(5)P-d5 ammonium
    ≥99.0%
    (Rac)-16:0 PI(5)P-d5 (ammonium) is deuterium labeled (Rac)-16:0 PI(5)P (ammonium).
    (Rac)-16:0 PI(5)P-d<sub>5</sub> ammonium
  • HY-132417S
    (rac)-N,O-Didesmethyl Tramadol-d3
    (rac)-N,O-Didesmethyl Tramadol-d3 is a deuterium labeled (rac)-N,O-Didesmethyl Tramadol. (rac)-N,O-Didesmethyl Tramadol is the main metabolite of Tramadol.
    (rac)-N,O-Didesmethyl Tramadol-d<sub>3</sub>
  • HY-W008807S
    Phosphoenolpyruvic acid potassium-13C2
    Phosphoenolpyruvic acid (potassium)-13C2 is the 13C labeled Phosphoenolpyruvic acid potassium (HY-W008807). Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties.
    Phosphoenolpyruvic acid potassium-<sup>13</sup>C<sub>2</sub>
  • HY-B2219S7
    Stearic acid-d4
    99.80%
    Stearic acid-d4 is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
    Stearic acid-d<sub>4</sub>