Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (2)

Isotope-Labeled Compounds Related Products (9621):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-107343S1

Docosahexaenoic acid ethyl ester-d₅-1
Docosahexaenoic acid ethyl ester-d₅-1 is the deuterium labeled Docosahexaenoic acid ethyl ester. Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects.

HY-W009162S5

Cytidine 5′-monophosphate-¹³C₉,¹⁵N₃ dilithium		99.80%
Cytidine 5′-monophosphate-¹³C₉,¹⁵N₃ (5'-Cytidylic acid-¹³C₉,¹⁵N₃ dilithium; 5'-CMP-¹³C₉,¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-125527S

Resolvin D1-d₅		99.2%
Resolvin D1-d₅ is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages.

HY-W016812S

Orotic acid-¹⁵N₂ hydrate		99.94%
Orotic acid-¹⁵N₂ is the ¹⁵N hydrate labeled Orotic acid hydrate. Orotic acid hydrate is an endogenous metabolite.

HY-W067028S

Semicarbazide-¹³C,¹⁵N₂ hydrochloride		99.86%
Semicarbazide-¹³C,¹⁵N₂ hydrochloride is ¹⁵N and ¹³C labeled Semicarbazide.

HY-B1455S1

Clindamycin-¹³C,d₃		≥99.0%
Clindamycin-¹³C,d₃ is the ¹³C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria.

HY-W393970S3

2′-Deoxyguanosine 5′-monophosphate-¹³C₁₀,¹⁵N₅ dilithium		99.8%
2′-Deoxyguanosine 5′-monophosphate-¹³C₁₀,¹⁵N₅ (5'-Deoxyguanylic acid-¹³C₁₀,¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).

HY-N8016S

Nonanal-d₁₈
Nonanal-d₁₈ is the deuterium labeled Nonanal. Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity.

HY-146906S

C18 Glucosyl(ß) ceramide-d₅
C18 Glucosyl(ß) ceramide-d₅ is deuterium labeled C18 Glucosyl(ß) ceramide.

HY-W742012

Clencyclohexerol-d₁₀		99.46%
Clencyclohexerol-d₁₀ is the deuterium-labeled Clencyclohexerol (HY-117406). Clencyclohexerol-d₁₀ is a β-agonist. Clencyclohexerol-d₁₀ can be used as a growth promoter in animals.

HY-W017387S2

Sodium α-ketoisocaproic acid-¹³C₆		99.3%
Sodium α-ketoisocaproic acid-¹³C₆ is the ¹³C labeled Sodium α-ketoisocaproic acid.

HY-B0673S1

Deupirfenidone-d₃		99.60%
Deupirfenidone-d₃ is the deuterium labeled Pirfenidone (HY-B0673). Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities.

HY-14648S5

Dexamethasone-d₃-1		98.02%
Dexamethasone-d₃-1 (Hexadecadrol-d₃-1; Prednisolone F-d₃-1) is a deuterium labeled Dexamethasone (HY-14648). Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-15592S1

Cabotegravir-d₅		99.31%
Cabotegravir-d₅ is deuterium labeled Cabotegravir.

HY-146836S

(Rac)-16:0 PI(5)P-d₅ ammonium		≥99.0%
(Rac)-16:0 PI(5)P-d₅ (ammonium) is deuterium labeled (Rac)-16:0 PI(5)P (ammonium).

HY-132417S

(rac)-N,O-Didesmethyl Tramadol-d₃
(rac)-N,O-Didesmethyl Tramadol-d₃ is a deuterium labeled (rac)-N,O-Didesmethyl Tramadol. (rac)-N,O-Didesmethyl Tramadol is the main metabolite of Tramadol.

HY-W008807S

Phosphoenolpyruvic acid (potassium)-¹³C₂
Phosphoenolpyruvic acid (potassium)-¹³C₂ is the ¹³C labeled Phosphoenolpyruvic acid potassium (HY-W008807). Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties.

HY-B2219S7

Stearic acid-d₄		99.80%
Stearic acid-d₄ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-Y1117S2

Melamine-¹⁵N₃,¹³C₃
Melamine-¹⁵N₃,¹³C₃ is a ¹³C- and ¹⁵N-labeled Melamine (HY-Y1117). Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials.

HY-161022S

FL118-C3-O-C-amide-C-NH2-d₅
FL118-C3-O-C-amide-C-NH2-d₅ is a deuterium labeled FL118-C3-O-C-amide-C-NH2.

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