Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (2)

Isotope-Labeled Compounds Related Products (9621):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0579S2

Cyclosporin A acetate-d₄		99.90%
Cyclosporin A acetate-d₄ (Cyclosporine A acetate-d₄; Ciclosporin A acetate-d₄) is a deuterium labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.

HY-141931S

Glycolithocholic acid 3-sulfate-d₄ sodium
Glycolithocholic acid 3-sulfate-d₄ (sodium) is the deuterium labeled Glycolithocholic acid 3-sulfate.

HY-W010589S

H-Abu-OH-d₃		≥99.0%
H-Abu-OH-d₃ is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.

HY-N0455AS5

L-Arginine-1,2-¹³C₂ hydrochloride		98.9%
L-Arginine-1,2-¹³C₂ (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-152072S

Deoxynivalenol-¹³C₁₅		98.60%
Deoxynivalenol-¹³C₁₅ is the ¹³C labeled Deoxynivalenol.

HY-W018772S14

D-Ribose-d₅		99.10%
D-Ribose-d₅ is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein gl

HY-W017141S

2-Isobutyl-3-methoxypyrazine-d₃
2-Isobutyl-3-methoxypyrazine-d₃ is the deuterium labeled 2-Isobutyl-3-methoxypyrazine. 2-Isobutyl-3-methoxypyrazine is an aroma constituent in grapes andwines, green pepper and asparagus.

HY-138622S1

24:0 Lyso PC-d₄
24:0 Lyso PC-d₄4 is the deuterium labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery.

HY-14184S

Macitentan-d₄		98.03%
Macitentan-d₄ is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

HY-143876S

L-Argininosuccinic acid-¹³C₆,¹⁵N₄ barium, dihydrate
L-Argininosuccinic acid-¹³C₆,¹⁵N₄ (barium, dihydrate) is a ¹⁵N-labeled and ¹³C-labled labeled L-Argininosuccinic acid (barium, dihydrate).

HY-A0023AS

Alogliptin-¹³C,d₃
Alogliptin-¹³C,d₃ is the deuterium labeled Alogliptin. Alogliptin is a potent and selective inhibitor of DPP-4.

HY-143778S

Clavulanic acid methyl ester-¹³C,d₃
Clavulanic acid methyl ester-¹³C,d₃ is the deuterium and ¹³C labeled Clavulanic acid methyl ester.

HY-B0975S

Penicillin V-¹³C₆ potassium		99.8%
Penicillin V-¹³C₆ (potassium) is the ¹³C₆ labeled Penicillin V (potassium). Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis.

HY-Y0674S

Dicyandiamide-¹³C₂,¹⁵N₂		99.90%
Dicyandiamide-¹³C₂,¹⁵N₂ is the ¹⁵N₂ labeled Dicyandiamide.

HY-B0193AS

Prazosin-d₈ hydrochloride		99.78%
Prazosin-d8 hydrochloride is the deuterium labeled Prazosin hydrochloride. Prazosin hydrochloride is an alpha-adrenergic blocker.

HY-N0650S6

L-Serine1-¹³C,¹⁵N		98.90%
L-Serine1-¹³C,¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-13318S1

Oseltamivir acid-¹³C,d₃
Oseltamivir acid-13C,d3 (GS 4071-13C,d3; Ro 64-0802-13C,d3) is a 13C- and deuterium-labeled Oseltamivir acid (HY-13318). Oseltamivir acid is the active metabolite of Oseltamivir phosphate and inhibits influenza virus neuraminidase (IC₅₀=2 nM). Oseltamivir acid is orally active and can be used to study influenza A/B infections.

HY-125818S6

Cytidine-5'-triphosphate-¹⁵N₃ dilithium
Cytidine-5'-triphosphate-¹⁵N₃ (Cytidine triphosphate-¹⁵N₃ dilithium; 5'-CTP-¹⁵N₃) dilithium is ¹⁵N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-Y1117S

Melamine-¹⁵N₃		99.91%
Melamine-¹⁵N₃ is a ¹⁵N-labeled Melamine. Melamine is a metabolite?of?cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials.

HY-N0667S

L-Asparagine-¹³C₄,¹⁵N₂,d₈		99%
L-Asparagine-¹³C₄,¹⁵N₂,d₈ is the ¹³C-labeled and ¹⁵N-labeled L-Asparagine (HY-N0667). L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

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