Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitor (1)

Isotope-Labeled Compounds Related Products (7656):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W009762S

L-Lysine-¹³C₆,¹⁵N₂ dihydrochloride		99.40%
L-Lysine-¹³C₆,¹⁵N₂ (dihydrochloride) is a ¹⁵N-labeled and ¹³C-labled L-Lysine dihydrochloride[1].

HY-N0658S6

L-Threonine-¹³C₄		≥98.0%
L-Threonine-¹³C₄ is the ¹³C labeled L-Threonine[1]. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[2].

HY-N0771S2

L-Isoleucine-¹⁵N		98.00%
L-Isoleucine-15N is the 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid.

HY-B0351S2

Taurine-¹³C₂,¹⁵N		98.60%
Taurine-¹³C₂,¹⁵N is the ¹³C- and ¹⁵N- labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].

HY-Y0669S

Pipecolic acid-d₉		99.59%
Pipecolic acid-d₉ is the deuterium labeled Pipecolic acid. Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy.

HY-W259489S

Picolinic acid-d₄		≥99.0%
Ppicolinic-3,4,5,6-d₄ acid is the deuterium labeled Ppicolinic acid[1].

HY-76082S

L-Pyroglutamic acid-d₅		98.6%
L-Pyroglutamic acid-d₅ is the deuterium labeled L-Pyroglutamic acid (HY-76082). L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-10219S

Rapamycin-d₃
Rapamycin-d₃ is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.

HY-42487S

Exatecan Intermediate 1-d₅		99.90%
Exatecan Intermediate 1-d₅ is the deuterium labeled Exatecan Intermediate 1.

HY-10162S

Olaparib-d₅		≥99.0%
Olaparib-d₅ (AZD2281-d₅) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC₅₀s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator.

HY-B0228S13

Adenosine-¹³C₁₀		99.00%
Adenosine-¹³C₁₀ (Adenine riboside-¹³C₁₀; D-Adenosine-¹³C₁₀) is ¹³C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-W016823S

p-Tyramine-d₄ hydrochloride		99.52%
p-Tyramine-d₄ (hydrochloride) is the deuterium labeled Tyramine hydrochloride. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1][2].

HY-101037S1

Sarcosine-d₃		99.05%
Sarcosine-d₃ is the deuterium labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

HY-134928AS

Pyridinium bisretinoid A2E-d₄ TFA
Pyridinium bisretinoid A2E-d₄ TFA is the deuterium-labeled Pyridinium bisretinoid A2E (HY-134928). Pyridinium bisretinoid A2E (A2E)is an initiator of blue-light-induced apoptosis. Photoactivation of Pyridinium bisretinoid A2E mediates autophagy and the production of reactive oxygen species.

HY-P0014S1

Liraglutide-¹³C₅,¹⁵N TFA		98.19%
Liraglutide-¹³C₅,¹⁵N (tetraTFA) is the ¹³C and ¹⁵N labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

HY-N0667S5

L-Asparagine-d₃ hydrate		99.64%
L-Asparagine-d₃ hydrate is the deuterium labeled L-Asparagine (HY-N0667). L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

HY-W010209S2

DL-Histidine-d₃		≥99.0%
DL-Histidine-d₃ is the deuterium labeled DL-Histidine.

HY-B2176S5

ATP-¹⁵N₅ dilithium		≥99.0%
ATP-¹⁵N₅ (Adenosine 5'-triphosphate-¹⁵N₅) dilithium is ¹⁵N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-N0100S

Naringenin-d₄		99.88%
Naringenin-d₄ is the deuterated version of Naringenin (HY-N0100). Naringenin shows strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity[1].

HY-B1453S

L-Carnitine-d₃ hydrochloride		≥98.0%
L-Carnitine-d₃ (hydrochloride) is the deuterium labeled L-Carnitine hydrochloride[1].

Name
Email *

	Sorry, but the email address you supplied was invalid.