2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9805):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-144427S
    Vitamin E-13C2,d6
    		98.0%
    Vitamin E-13C2,d6 is a 13C-labeled and deuterium labeled Vitamin E.
    Vitamin E-<sup>13</sup>C<sub>2</sub>,d<sub>6</sub>
  • HY-150707S
    DL-A-phosphatidylcholine, dipalmitoyl-13C40
    DL-A-phosphatidylcholine, dipalmitoyl-13C40 is the 13C labeled DL-A-phosphatidylcholine, dipalmitoyl.
    DL-A-phosphatidylcholine, dipalmitoyl-<sup>13</sup>C<sub>40</sub>
  • HY-13904S
    Flumatinib-d3
    		98.44%
    Flumatinib-d3 is deuterium labeled Flumatinib. Flumatinib (HHGV678) is an orally available, selective inhibitor of Bcr-Abl. Flumatinib inhibits c-Abl, PDGFRβ and c-Kit with IC50s of 1.2 nM, 307.6 nM and 665.5 nM, respectively.
    Flumatinib-d<sub>3</sub>
  • HY-W012382S
    N-Acetyl-L-tyrosine-d3
    		98.43%
    N-Acetyl-L-tyrosine-d3 is the deuterated form of N-Acetyl-L-tyrosine (HY-W012382). N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer.
    N-Acetyl-L-tyrosine-d<sub>3</sub>
  • HY-13757S
    Tamoxifen-d3 hydrochloride
    		98.99%
    Tamoxifen-d3 hydrochloride is deuterated labeled Tamoxifen (Citrate) (HY-13757). Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells.Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively. Tamoxifen Citrate activates autophagy and induces apoptosis.Tamoxifen Citrate also can induce gene knockout of CreER(T2) transgenic mouse.
    Tamoxifen-d<sub>3</sub> hydrochloride
  • HY-W134007S1
    Hexadecanoate-13C16 potassium
    		98.40%
    Hexadecanoate-13C16 (potassium) is the 13C-labeled Hexadecanoate sodium. Hexadecanoate potassium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
    Hexadecanoate-<sup>13</sup>C<sub>16</sub> potassium
  • HY-146929S
    18:1 SM (d18:1/18:1)-d9
    		≥99.0%
    18:1 SM (d18:1/18:1)-d9 is deuterium labeled 18:1 SM (d18:1/18:1).
    18:1 SM (d18:1/18:1)-d<sub>9</sub>
  • HY-103252S2
    Monomethyl fumarate-d2
    		98.19%
    Monomethyl fumarate-d2 is a deuterium labeled Monomethyl fumarate (HY-103252). Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF) (HY-17363), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease.
    Monomethyl fumarate-d<sub>2</sub>
  • HY-100573S
    Necrosulfonamide-d4
    		99.26%
    Necrosulfonamide-d4 is the deuterium labeled Necrosulfonamide (HY-100573). Necrosulfonamide, a necroptosis and gasdermin D inhibitor, selectively targets (MLKL). Necrosulfonamide prevents the MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a key substrate of RIP3 in the induction of necrosis.
    Necrosulfonamide-d<sub>4</sub>
  • HY-66011AS
    Moxifloxacin-d4
    Moxifloxacin-d4 is the deuterium labeled Moxifloxacin. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
    Moxifloxacin-d<sub>4</sub>
  • HY-78131CS
    Ibuprofen-d3 sodium
    		≥99.0%
    Ibuprofen-d3 ((±)-Ibuprofen-d3) sodium is the deuterium labeled Ibuprofen sodium (HY-78131C). Ibuprofen sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.
    Ibuprofen-d<sub>3</sub> sodium
  • HY-151911S
    Mono-Cyclohexyl Phthalate-3,4,5,6-d4
    		99.07%
    Mono-Cyclohexyl Phthalate-3,4,5,6-d4 is the deuterium labeled Mono-Cyclohexyl Phthalate.
    Mono-Cyclohexyl Phthalate-3,4,5,6-d<sub>4</sub>
  • HY-76082S1
    L-Pyroglutamic acid-13C5
    L-Pyroglutamic acid-13C5 is the 13C labeled L-Pyroglutamic acid (HY-76082). L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE).
    L-Pyroglutamic acid-<sup>13</sup>C<sub>5</sub>
  • HY-113254S1
    13,14-Dihydro-15-keto-PGE2-d9
    		≥99.0%
    13,14-Dihydro-15-keto-PGE2-d9 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2.
    13,14-Dihydro-15-keto-PGE2-d<sub>9</sub>
  • HY-118774S
    Propofol-d17 β-D-glucuronide
    		≥98.0%
    Propofol-d17 β-D-glucuronide is the deuterium labeled Propofol β-D-glucuronide.
    Propofol-d<sub>17</sub> β-D-glucuronide
  • HY-Y0194S
    2-Aminohexane-d6
    2-Aminohexane-d6 is the deuterium labeled 2-Aminohexane.
    2-Aminohexane-d<sub>6</sub>
  • HY-146795S
    15:0-18:1 DG-d7
    		≥99.0%
    15:0-18:1 DG-d7 is deuterium labeled 15:0-18:1 DG.
    15:0-18:1 DG-d<sub>7</sub>
  • HY-143922S
    N-Desmethyl Bedaquiline-d6
    N-Desmethyl Bedaquiline-d6 is the deuterium labeled N-Desmethyl Bedaquiline.
    N-Desmethyl Bedaquiline-d<sub>6</sub>
  • HY-50935S
    Troglitazone-d4
    		98.19%
    Troglitazone-d4 is deuterium labeled Troglitazone. Troglitazone is a PPARγ agonist, with EC50s of 550 nM and 780 nM for human and murine PPARγ receptor, respectively.
    Troglitazone-d<sub>4</sub>
  • HY-W131353S
    Hexatriacontane-d74
    		≥99.0%
    Hexatriacontane-d74 is the deuterium labeled Hexatriacontane.
    Hexatriacontane-d<sub>74</sub>