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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9621):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-15660S
    Efinaconazole-d4
    99.91%
    Efinaconazole-d4 is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species.
    Efinaconazole-d<sub>4</sub>
  • HY-W004356S
    (Rac)-Tenofovir alafenamide-d5
    98.13%
    (2R)-Isopropyl 2-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate-d5 is the deuterium labeled (2R)-isopropyl 2-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate[
    (Rac)-Tenofovir alafenamide-d<sub>5</sub>
  • HY-10274S
    Dabigatran etexilate-d13
    99.28%
    Dabigatran etexilate-d13 is the deuterium labeled Dabigatran etexilate. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran. Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation.
    Dabigatran etexilate-d<sub>13</sub>
  • HY-W014225S
    3-Phenoxybenzoic acid-13C6
    99.29%
    3-Phenoxybenzoic acid-13C6 is the 13C6 labeled 3-Phenoxybenzoic acid. 3-Phenoxybenzoic acid is the metabolite of pyrethroid insecticides. 3-Phenoxybenzoic acid induces immunotoxicity and oxidative stress, and inhibits the phagocytic ability of macrophages.
    3-Phenoxybenzoic acid-<sup>13</sup>C<sub>6</sub>
  • HY-14397S
    Indomethacin-d4
    99.78%
    Indomethacin-d4 is a deuterium labeled Indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes.
    Indomethacin-d<sub>4</sub>
  • HY-163164S
    18:1-17:1-18:1 TG-d5
    99.00%
    18:1-17:1-18:1 TG-d5, 1,3-dioleoyl-2-heptadec-10Z-enoyl-glycerol-d5, is a deuterated substance.
    18:1-17:1-18:1 TG-d<sub>5</sub>
  • HY-15656S
    Ceritinib-d7
    98.00%
    Ceritinib-d7 is a deuterium labeled Ceritinib. Ceritinib is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor.
    Ceritinib-d<sub>7</sub>
  • HY-17413S1
    Zidovudine-13C,d3
    Zidovudine-13C,d3 is the 13C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.
    Zidovudine-<sup>13</sup>C,d<sub>3</sub>
  • HY-B0151S
    Pregnenolone-d4
    Pregnenolone-d4 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels.
    Pregnenolone-d<sub>4</sub>
  • HY-78139S1
    L-Xylose-2-13C
    L-Xylose-2-13C ((L-(-)-Xylose-2-13C)) is the 13C labeled L-Xylose (HY-78139). L-Xylose (L-(-)-Xylose) is a rare sugar and the levorotatory form of Xylose (HY-N0537). L-Xylose can be used as a raw material for the synthesis of various drugs and bioactive molecules.
    L-Xylose-2-<sup>13</sup>C
  • HY-W440409
    2,2′-Bipyridine-d8
    99.33%
    2,2′-Bipyridine-d8 is the deuterium labeled 2,2′-Bipyridine-d8.
    2,2′-Bipyridine-d<sub>8</sub>
  • HY-B0390S
    Mestranol-d2
    ≥99.0%
    Mestranol-d2 is the deuterium labeled Mestranol. Mestranol is an inactive proagent and becomes biologically active on conversion to ethinyl estradiol (EE). Mestranol acts as an estrogen receptor agonist. Mestranol combines with a progestin in vivo and can be used for the research of menopausal hormone or menstrual disorders. Mestranol-d2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Mestranol-d<sub>2</sub>
  • HY-127035S2
    Tristearin-d40
    99.12%
    Tristearin-d40 is the deuterium labeled Tristearin.
    Tristearin-d<sub>40</sub>
  • HY-W127457S
    1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d22
    ≥99.0%
    1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d22 is deuterium labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine.
    1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d<sub>22</sub>
  • HY-N0684S3
    Vitamin K1-13C6
    ≥99.0%
    Vitamin K1-13C6 is the 13C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
    Vitamin K1-<sup>13</sup>C<sub>6</sub>
  • HY-W141857
    L-Alanine-2-d1
    L-Alanine-2-d1 is the deuterium labeled L-Alanine-2[1].
    L-Alanine-2-d1
  • HY-B0152S4
    Adenine-15N5
    Adenine-15N5 (6-Aminopurine-15N5; Vitamin B4-15N5) is 15N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
    Adenine-<sup>15</sup>N<sub>5</sub>
  • HY-A0003S
    Lenalidomide-d5
    99.32%
    Lenalidomide-d5 is deuterium labeled Lenalidomide. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.
    Lenalidomide-d<sub>5</sub>
  • HY-B1556S
    Benzyl salicylate-d4
    ≥99.0%
    Benzyl salicylate-d4 is the deuterium labeled Benzyl salicylate.
    Benzyl salicylate-d<sub>4</sub>
  • HY-132953S
    Formaldehyde 2,4-dinitrophenylhydrazone-d3
    ≥99.0%
    Formaldehyde 2,4-dinitrophenylhydrazone-d3 is the deuterium labeled Formaldehyde 2,4-dinitrophenylhydrazone.
    Formaldehyde 2,4-dinitrophenylhydrazone-d<sub>3</sub>