Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (2)

Isotope-Labeled Compounds Related Products (9620):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W010256S

D-Xylulose-1-¹³C		99.22%
D-Xylulose-1-¹³C is the ¹³C labeled D-Xylulose. D-xylulose is a precursor of the pentiol D-arabi.

HY-W002300S

Boc-L-Valine-d₈		99.62%
Boc-L-Valine-d₈ is the deuterium labeled Boc-L-Valine.

HY-W015301S2

Dimethyl adipate-d₈		≥98.0%
Dimethyl adipate-d₈ is the deuterium labeled Dimethyl adipate.

HY-Y0366S2

Lauric acid-d₂		99.80%
Lauric acid-d₂ is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.

HY-B0579S3

Cyclosporin A-¹³C₂,d₄
Cyclosporin A-¹³C₂,d₄ (Cyclosporine A-¹³C₂,d₄; Ciclosporin A-¹³C₂,d₄) is a ¹³C labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.

HY-N0108S

Physcion-d₃		99.82%
Physcion-d₃ (Parietin-d₃) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC₅₀ and a K_d of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.

HY-Y1359S

2-Methylimidazole-d₆
2-Methylimidazole-d₆ is the deuterium labeled 2-Methylimidazole.

HY-145008S

(±)9(10)-DiHOME-d₄		99.00%
(±)9(10)-DiHOME-d₄ is the deuterium labeled (±)9(10)-DiHOME.

HY-12715S1

Yohimbine-d3		≥99.0%
Yohimbine-d3 is the deuterium labeled Yohimbine (HY-12715).

HY-N1428S3

Citric acid-¹³C₃
Citric acid-¹³C₃ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.

HY-146712S

N-(4-Hydroxyphenyl)acetamide sulfate-d₃ sodium
N-(4-Hydroxyphenyl)acetamide sulfate-d₃ (sodium) is the deuterium labeled N-(4-Hydroxyphenyl)acetamide sulfate.

HY-10888S

Istradefylline-¹³C,d₃
Istradefylline-¹³C,d₃ is the ¹³C- and deuterium labeled Istradefylline. Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.

HY-B1328S

Pyridoxine-d₅
Pyridoxine-d₅ (Pyridoxol-d₅) is a deuterium labeled Pyridoxine (HY-B1328). Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-B0271S

Pyrazinamide-d₃		99.84%
Pyrazinamide-d₃ is deuterium labeled Pyrazinamide. Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.

HY-N0168AS1

(Rac)-Hesperetin-¹³C,d₃		99.3%
(Rac)-Hesperetin-¹³C,d₃ is the ¹³C- and deuterium labeled (Rac)-Hesperetin. (Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation.

HY-18260S6

Bisphenol A-d₁₄		99.74%
Bisphenol A-d₁₄ is a deuterium labeled Bisphenol A (HY-18260). Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders.

HY-W010590S1

H-DL-Abu-OH-d₆		99.94%
H-DL-Abu-OH-d₆ is the deuterium labeled H-DL-Abu-OH.

HY-W131845S

Ethephon-d₄
Ethephon-d₄ is the deuterium labeled Ethephon.

HY-146933S

24:1 SM (d18:1/24:1)-d₉
24:1 SM (d18:1/24:1)-d₉ is deuterium labeled 24:1 SM (d18:1/24:1).

HY-B1871S

Metolachlor-d₆		98.58%
Metolachlor-d₆ is the deuterium labeled Metolachlor. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers.

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