2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9979):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W585839S
    Bis(2-chloroethyl) phosphate-d8
    		99.90%
    Bis(2-chloroethyl) phosphate-d8 is a deuterium labeled compound.
    Bis(2-chloroethyl) phosphate-d<sub>8</sub>
  • HY-W016498S1
    Paraxanthine-13C4,15N3
    		99.80%
    Paraxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.
    Paraxanthine-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>3</sub>
  • HY-169326S
    JAK2-IN-11
    		98.03%
    JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with IC50 ≤10 nM against JH2 BIND WT/V617F. JAK2-IN-11 has antitumor activity.
    JAK2-IN-11
  • HY-113225S3
    Guanosine triphosphate-15N5 dilithium
    Guanosine triphosphate-15N5 (GTP-15N5) dilithium is 15N labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
    Guanosine triphosphate-<sup>15</sup>N<sub>5</sub> dilithium
  • HY-W026772S
    Fluorene-d10
    		99.0%
    Fluorene-d10 is the deuterium labeled Fluorene. Fluorene, a polycyclic aromatic hydrocarbon (PAH), is a precursor to other fluorene compounds. Fluorene and its derivative?can be used as a precursor to fluorene-based dyes.
    Fluorene-d<sub>10</sub>
  • HY-113144AS
    L-Hexanoylcarnitine-d3 chloride
    		99.0%
    L-Hexanoylcarnitine-d3 (chloride) is the deuterium labeled L-Hexanoylcarnitine chloride.
    L-Hexanoylcarnitine-d<sub>3</sub> chloride
  • HY-107819S
    5α-Cholestan-3β-ol-d5
    		99.18%
    5α-Cholestan-3β-ol-d5 is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound.
    5α-Cholestan-3β-ol-d<sub>5</sub>
  • HY-142117S
    6-Sulfatoxy Melatonin-d4 sodium
    		99.25%
    6-Sulfatoxy Melatonin-d4 sodium is the deuterium labeled 6-Sulfatoxy Melatonin sodium.
    6-Sulfatoxy Melatonin-d4 sodium
  • HY-W015998S
    (R)-(+)-Warfarin-d5
    		99.23%
    (R)-(+)-Warfarin-d5 is deuterium labeled (R)-(+)-Warfarin.
    (R)-(+)-Warfarin-d<sub>5</sub>
  • HY-B0254S
    Glipizide-d11
    Glipizide-d11 is the deuterium labeled Glipizide. Glipizide (CP 2872; K 4024)?a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2?diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium?(KATP) channels among β cells of pancreatic islets of Langerhans.
    Glipizide-d<sub>11</sub>
  • HY-130321S1
    Lauroyl-L-carnitine-d9 chloride
    		98.0%
    Lauroyl-L-carnitine-d9 (chloride) is the deuterium labeled Lauroyl-L-carnitine chloride (HY-130321). Lauroyl-L-carnitine chloride is an orally active absorption enhancer. Lauroyl-L-carnitine chloride improves the oral bioavailability of peptide compounds.
    Lauroyl-L-carnitine-d<sub>9</sub> chloride
  • HY-14879S2
    Avibactam sodium salt-13C5
    		99.9%
    Avibactam sodium salt-13C5 (NXL-104-13C5) is 13C labeled Avibactam (sodium). Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.
    Avibactam sodium salt-<sup>13</sup>C<sub>5</sub>
  • HY-B1221S1
    Flufenamic acid-13C6
    Flufenamic acid-13C6 is the 13C6 labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
    Flufenamic acid-<sup>13</sup>C<sub>6</sub>
  • HY-B0099S
    Edaravone-d5
    		99.52%
    Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
    Edaravone-d<sub>5</sub>
  • HY-165607S
    MCB-22-174
    		99.78%
    MCB-22-174 is a deuterated Piezo1 agonist, with an EC50 value of 6.28 μM. MCB-22-174 remarkably activates the CaMKII/ERK signaling pathway and initiates Ca2+ influx in rMSCs. MCB-22-174 significantly decreases the expression of chondrogenesis markers (Comp, Acan) and adipogenesis markers (Lpl, Fabp4) in MSCs. MCB-22-174 can effectively improve bone quality in hind-limb unloading (HU) model rats. MCB-22-174 can be used for the study of disuse osteoporosis (OP).
    MCB-22-174
  • HY-W440409
    2,2′-Bipyridine-d8
    		99.33%
    2,2′-Bipyridine-d8 is the deuterium labeled 2,2′-Bipyridine-d8.
    2,2′-Bipyridine-d<sub>8</sub>
  • HY-Y0337S6
    L-Cysteine-d2
    		98.67%
    L-Cysteine-d2 is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.
    L-Cysteine-d<sub>2</sub>
  • HY-B0172AS
    Isoallolithocholic acid-d2
    		99.28%
    Isoallolithocholic acid-d2 is the deuterium labeled Isoallolithocholic acid (HY-B0172A). Isoallolithocholic acid is a T cell regulator and enhances regulatory T cells (Tregs) differentiation.
    Isoallolithocholic acid-d<sub>2</sub>
  • HY-N0486S4
    L-Leucine-d7
    		99.91%
    L-Leucine-d7 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
    L-Leucine-d<sub>7</sub>
  • HY-W012340S
    L-Homoarginine-13C7,15N4 hydrochloride
    		98.0%
    L-Homoarginine-13C7,15N4 (hydrochloride) is the 13C- and 15N-labeled H-HomoArg-OH.HCl. H-HomoArg-OH.HCl is an endogenous metabolite.
    L-Homoarginine-<sup>13</sup>C<sub>7</sub>,<sup>15</sup>N<sub>4</sub> hydrochloride