2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9620):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W643348
    4-Bromoiodobenzene-d4
    4-Bromoiodobenzene-d4 is the deuterium labeled 4-Bromoiodobenzene (HY-W086988).
    4-Bromoiodobenzene-d<sub>4</sub>
  • HY-13948BS
    Angiotensin II human-13C6,15N TFA
    		98.11%
    Angiotensin II human-13C6,15N TFA (Ang II-13C6,15N TFA) is 13C- and 15N-labeled Angiotensin II human (TFA) (HY-13948B). Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions.
    Angiotensin II human-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N TFA
  • HY-W099646S1
    N-Octanoylglycine-2,2-d2
    		99.10%
    N-Octanoylglycine-2,2-d2 is the deuterium labeled N-Octanoylglycine-2,2.
    N-Octanoylglycine-2,2-d<sub>2</sub>
  • HY-B0528S
    Octopamine-d3
    		99.52%
    Octopamine-d3 is deuterium labeled Octopamine.
    Octopamine-d<sub>3</sub>
  • HY-W013494S
    L-Carnosine-d4
    		99.00%
    L-Carnosine-d4 is the deuterium labeled L-Carnosine. L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging.
    L-Carnosine-d<sub>4</sub>
  • HY-N2427S
    Adamantane-d16
    		98.40%
    Adamantane-d16is the deuterium labeled Adamantane (HY-N2427). Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery.
    Adamantane-d<sub>16</sub>
  • HY-W131797
    1-Iodoethane-1,1,2,2,2-d5
    		99.58%
    1-Iodoethane-1,1,2,2,2-d5 is the deuterium labeled 1-Iodoethane.
    1-Iodoethane-1,1,2,2,2-d<sub>5</sub>
  • HY-109541S2
    Colfosceril miristate-d9
    		≥99.0%
    Colfosceril miristate-d9 (DMPC-d9) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery.
    Colfosceril miristate-d<sub>9</sub>
  • HY-13010S
    Laquinimod-d5
    		98.25%
    Laquinimod-d5 (ABR-215062-d5) is deuterium labeled Laquinimod. Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator that prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing-remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research.
    Laquinimod-d<sub>5</sub>
  • HY-138253S
    2′,2′-Difluorodeoxyuridine-13C,15N2
    		99.50%
    2′,2′-Difluorodeoxyuridine-13C,15N2 (dFdU-13C,15N2) is a 13C- and 15N-labeled compound. 2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells.
    2′,2′-Difluorodeoxyuridine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-17412S1
    Minocycline-d6 sulfate
    Minocycline-d6 sulfate is deuterated labeled Minocycline (HY-17412A). Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect.
    Minocycline-d<sub>6</sub> sulfate
  • HY-113320S
    Etiocholanolone-d5
    		99.20%
    Etiocholanolone-d5 is the deuterium labeled Etiocholanolone. Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent?neurosteroid positive allosteric modulator?(PAM) of the GABAA?receptor than its?enantiomer form.
    Etiocholanolone-d<sub>5</sub>
  • HY-Y0338S
    Ethylene glycol-(OD)2
    		99.05%
    Ethylene glycol-(OD)2 is the deuterium labeled Ethylene glycol.
    Ethylene glycol-(OD)<sub>2</sub>
  • HY-N1981S1
    Triolein-d5
    Triolein-d5 is the deuterium labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties.
    Triolein-d<sub>5</sub>
  • HY-143936S
    Chloroxuron-d6
    		98.75%
    Chloroxuron-d6 is the deuterium labeled Chloroxuron.
    Chloroxuron-d<sub>6</sub>
  • HY-W018392S
    Mono-(2-ethylhexyl) phthalate-d4
    		99.71%
    Mono-(2-ethylhexyl) phthalate-d4 is a deuterium labeled Mono-(2-ethylhexyl) phthalate (HY-W018392). Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD).
    Mono-(2-ethylhexyl) phthalate-d<sub>4</sub>
  • HY-B0244S
    Praziquantel-d11
    		99.58%
    Praziquantel-d11 is the deuterium labeled Praziquantel, which is an anthelmintic.
    Praziquantel-d<sub>11</sub>
  • HY-W026772S1
    Fluorene-d8
    Fluorene-d8 is the deuterium labeled Fluorene (HY-W026772). Fluorene is an orally active polycyclic aromatic hydrocarbon (PAH) and a precursor to other fluorene-based compounds. Fluorene and its derivatives serve as dye precursors for fluorene synthesis. In A549 cells, Fluorene induces oxidative stress and inflammatory responses by increasing ROS and SOD generation, exacerbating lipid peroxidation, modulating antioxidant enzyme activity, and upregulating the expression of pro-inflammatory factors TNF-α and IL-6. In vivo, Fluorene exhibits anxiolytic activity. Fluorene holds potential for research in inflammation and neurological disorders.
    Fluorene-d<sub>8</sub>
  • HY-17004S1
    Olmesartan-d6
    		98.68%
    Olmesartan-d6 (RNH-6270-d6) is the deuterium labeled Olmesartan. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure.
    Olmesartan-d<sub>6</sub>
  • HY-W759404
    Clascoterone-d5
    Clascoterone-d5 (Cortexolone 17 alpha-propionate-d5) is the deuterated analog of Clascoterone. Clascoterone is a topical and peripheral androgen antagonist.
    Clascoterone-d<sub>5</sub>