2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7662):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W587397S
    Benzoic acid, 4,4′-[[6-[[4-[[(1,1-dimethy-d4
    Benzoic acid, 4,4′-[[6-[[4-[[(1,1-dimethy-d4 is deuterium labeled Benzoic acid, 4,4′-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-, 1,1′-bis(2-ethylhexyl) ester.
    Benzoic acid, 4,4′-[[6-[[4-[[(1,1-dimethy-d<sub>4</sub>
  • HY-17430S2
    Amprenavir-13C6
    Amprenavir-13C6 (VX-478-13C6) is 13C labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM.
    Amprenavir-<sup>13</sup>C<sub>6</sub>
  • HY-B1276S
    Metaproterenol-d7 hemisulfate
    Metaproterenol-d7 (hemisulfate) is the deuterium labeled Metaproterenol hemisulfate. Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity[1][2].
    Metaproterenol-d<sub>7</sub> hemisulfate
  • HY-W726709
    Propachlor ESA-d5 sodium
    Propachlor ESA-d5 (2-[(1-Methylethyl)phenylamino-d5]-2-oxoethanesulfonic acid) sodiumis deuterium labeled Sodium 2-(isopropyl(phenyl)amino)-2-oxoethane-1-sulfonate.
    Propachlor ESA-d<sub>5</sub> sodium
  • HY-133680S
    β-Tocopherol-d4
    β-Tocopherol-d4 is a deuterium labeled β-Tocopherol (HY-133680). β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol.
    β-Tocopherol-d<sub>4</sub>
  • HY-W653896
    Alternariol-d2
    Alternariol-d2 is deuterium labeled Alternariol. Alternariol is an orally ingested mycotoxin produced by Alternaria, capable of inhibiting the activity of topoisomerase I and II (topoisomerase I, topoisomerase II). Alternariol has weak estrogenic (Estrogen Receptor/ERR) and androgen/antiandrogen (Androgen Receptor) effects. Alternariol can induce apoptosis, trigger cell cycle arrest, suppress innate immune responses, and exhibit anti-tumor activity. Alternariol has genotoxic, mutagenic, and endocrine-disrupting effects.
    Alternariol-d<sub>2</sub>
  • HY-157050S
    3-Hydroxygepirone-d8
    3-Hydroxygepirone-d8 is deuterium-labeled 3-Hydroxygepirone.
    3-Hydroxygepirone-d<sub>8</sub>
  • HY-W743379
    (S)-N-Nitroso anatabine-d4
    (S)-N-Nitroso anatabine-d4 is deuterium labeled (S)-N-Nitroso Anatabine.
    (S)-N-Nitroso anatabine-d<sub>4</sub>
  • HY-17425AS1
    Valacyclovir-d4 hydrochloride
    Valacyclovir-d4 (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422)[1][2][3][4][5].
    Valacyclovir-d<sub>4</sub> hydrochloride
  • HY-B0121BS3
    Sumatriptan-d6 formate
    Sumatriptan-d6 (formate) (GR 43175 free base-d6 (formate)) is deuterium labeled Sumatriptan. Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan can be used for migraine headache research.
    Sumatriptan-d<sub>6</sub> formate
  • HY-173089S
    TPSLP(pT)PP(pT)REPK-(Lys-13C6,15N2) TFA
    TPSLP(pT)PP(pT)REPK-(Lys-13C6,15N2) TFA is the 13C- and 15N-labeled TPSLP(pT)PP(pT)REPK-(Lys) TFA.
    TPSLP(pT)PP(pT)REPK-(Lys-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>2</sub>) TFA
  • HY-20685S2
    Palmitoylethanolamide-d5
    Palmitoylethanolamide-d5 (Palmidol-d5, PEA-15,15,16,16,16-d5) is deuterium labeled Palmitoylethanolamide. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.
    Palmitoylethanolamide-d<sub>5</sub>
  • HY-15202S1
    Binimetinib-d3
    Binimetinib-d3 (MEK162-d3) is deuterium labeled Binimetinib. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM.
    Binimetinib-d<sub>3</sub>
  • HY-134127S1
    Methyl hexacosanoate-d4
    Methyl hexacosanoate-d4 (Methylhexacosanoat-d4) is deuterium labeled Methyl hexacosanoate. Methyl hexacosanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Methyl hexacosanoate-</sub>d<sub>4</sub>
  • HY-N0455AS9
    L-Arginine-15N4,d7 hydrochloride
    L-Arginine-15N4,d7 (hydrochloride) is the deuterium and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
    L-Arginine-<sup>15</sup>N<sub>4</sub>,d<sub>7</sub> hydrochloride
  • HY-W584477
    4,6-Dichloro-N-methylnicotinamide-d3
    4,6-Dichloro-N-methylnicotinamide-d3 is the deuterium labeled 4,6-Dichloro-N-methylnicotinamide.
    4,6-Dichloro-N-methylnicotinamide-d<sub>3</sub>
  • HY-17504AS1
    Rosuvastatin-d6
    Rosuvastatin-d6 (ZD 4522-d6) is deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
    Rosuvastatin-d<sub>6</sub>
  • HY-116687S
    7-Aminoflunitrazepam-d7
    7-Aminoflunitrazepam-d7 is deuterium labeled 7-Aminoflunitrazepam.
    7-Aminoflunitrazepam-d<sub>7</sub>
  • HY-W150958S
    Backebergine-d6
    Backebergine-d6 is the deuterium labeled Backebergine.
    Backebergine-d<sub>6</sub>
  • HY-W704657
    Monobutyl phosphate-d9
    Monobutyl phosphate-d9 is the deuterium labeled Monobutyl phosphate (HY-N7143). Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects.
    Monobutyl phosphate-d<sub>9</sub>