Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (2)

Isotope-Labeled Compounds Related Products (9619):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W040268S1

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d₉
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d₉ is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane.

HY-N0733S

Glucosamine-¹³C hydrochloride
Glucosamine-¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

HY-B0154S

Fluticasone propionate-d₃
Fluticasone propionate-d₃ is the deuterium labeled Fluticasone propionate. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity.

HY-W027553S1

Ipidacrine-d₁₀
Ipidacrine-d₉ (NIK-247-d₉ (free base)) is the deuterium labeled Ipidacrine (HY-W027553). Ipidacrine is orally active and brain-penetrant AChE and BuChE inhibitors with IC₅₀ values of 1 μM and 1.9 μM, respectively, which is also a partial agonist of M2-cholinergic receptors and a reversible cholinesterase inhibitor. Ipidacrine has a stimulating effect on neuromuscular transmission and excitation along the nerve fibres with a moderately anti-pain effect. Ipidacrine is an aminopyridines and is structurally similar to Tacrine (HY-111338). Ipidacrine is effective in various amnesia models, improves erectile function and inhibits K+ and Na+-channels in the neuronal membrane in diabetic rats. Ipidacrine is promising for research of Alzheimer’s disease, ischaemic stroke, idiopathic neuropathy of the facial nerve, diabetes mellitus-induced erectile dysfunction and other deficits in central or peripheral cholinergic deseases.

HY-14648S1

Dexamethasone-d₅-1
Dexamethasone-d₅-1 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-151912S

Picolinafen-d₄ (4-Fluorophenyl-d₄)
Picolinafen-d₄ (4-fluorophenyl-d₄) is the deuterium labeled Picolinafen.

HY-B0207AS1

Pyridostigmine-d₃ bromide
Pyridostigmine-d₃ (bromide) is the deuterium labeled Pyridostigmine bromide. Pyridostigmine bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.

HY-W009981S

1-Bromo-2,4-difluorobenzene-d₃
1-Bromo-2,4-difluorobenzene-d₃ is the deuterium labeled 1-Bromo-2,4-difluorobenzene.

HY-W752886

Estradiol 3-d₃ (β-D-Glucuronide) sodium
Estradiol 3-d₃ (β-D-Glucuronide) sodium is the deuterium labeled Estradiol 3-(β-D-Glucuronide) sodium (HY-N7755). Estradiol 3-(β-D-Glucuronide) sodium is the glucuronic acid derivative of estradiol (HY-B0141). Estradiol 3-(β-D-Glucuronide) sodium is radiolabeled for use in tumor imaging and biodistribution studies.

HY-W744235

Levofloxacin-d₃ sodium
Levofloxacin-d₃ sodium is the deuterium labeled Levofloxacin sodium (HY-B0330C). Levofloxacin ((-)-Ofloxacin) sodium is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin sodium inhibits the DNA gyrase and topoisomerase IV. Levofloxacin sodium can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin sodium shows anti-orthopoxvirus activity.

HY-W709612

Regorafenib N-oxide and N-desmethyl (M5)-d₃-1
Regorafenib N-oxide and N-desmethyl (M5)-d₃-1 (N-Desmethyl regorafenib N-oxide-d₃-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5) (HY-108226). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4.

HY-Y0127S

D(-)-2-Aminobutyric acid-d₆
D(-)-2-Aminobutyric acid-d₆ is the deuterium labeled D(-)-2-Aminobutyric acid. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

HY-W010153S

3-(Trifluoromethyl)phenol-d₄
3-(Trifluoromethyl)phenol-d₄ is the deuterium labeled 3-(Trifluoromethyl)phenol.

HY-150531S

Safinamide d₃
Safinamide d₃ is the deuterium labeled Safinamide.

HY-W451242

1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈
1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled 1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈.

HY-135336S

(R)-Verapamil-d₇ hydrochloride
(R)-Verapamil-d₇ (hydrochloride) is a deuterium labeled (R)-Verapamil hydrochloride. (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents.

HY-N1420AS2

Rhamnose-¹³C-2 monohydrate		≥99.0%
Rhamnose-¹³C-2 (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate

HY-W011222S1

1-Bromooctadecane-18,18,18-d₃
1-Bromooctadecane-18,18,18-d₃ is the deuterium labeled 1-Bromooctadecane.

HY-78571S

3-Methylbenzoic acid-d₇
3-Methylbenzoic acid-d₇ is the deuterium labeled 3-Methylbenzoic acid.

HY-W069504S

n-Propyl-amine-d₇ Hydrochloride
n-Propyl-amine-d₇ (Hydrochloride) is the deuterium labeled Propan-1-amine hydrochloride.

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