2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7664):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-167596S
    C18:0-d7 GD2 Ceramide (d18:1/18:0-d7)
    C18:0-d7 GD2 Ceramide (d18:1/18:0-d7) is deuterium labeled C18:0 GD2 Ceramide (d18:1/18:0).
    C18:0-d<sub>7</sub> GD2 Ceramide (d18:1/18:0-d<sub>7</sub>)
  • HY-W012837S
    Benzylmethylether-d2
    Benzylmethylether-d2 (Methoxymethylbenzene-d2) is the deuterium labeled (Methoxymethyl)benzene (HY-W012837).
    Benzylmethylether-d<sub>2</sub>
  • HY-W654306
    1-Palmitoyl-2-oleoyl-3-chloropropanediol-d5
    1-Palmitoyl-2-oleoyl-3-chloropropanediol-d5 is deuterium labeled 1-Palmitoyl-2-oleoyl-3-chloropropanediol. 1-Palmitoyl-2-oleoyl-3-chloropropanediol is an ester product.
    1-Palmitoyl-2-oleoyl-3-chloropropanediol-d<sub>5</sub>
  • HY-154744S
    Trimegestone sulfate pyridinium salt-13C,d3
    Trimegestone sulfate pyridinium salt-13C,d3 is 13C and deuterated labeled Trimegestone sulfate pyridinium salt.
    Trimegestone sulfate pyridinium salt-<sup>13</sup>C,d<sub>3</sub>
  • HY-106577S1
    Cibenzoline-d5
    Cibenzoline-d5 (Cifenline-d5) is deuterium labeled Cibenzoline. Cibenzoline is a class Ia antiarrhythmic active molecule with low anticholinergic activity. Cibenzoline is a KATP channel inhibitor, acting through the pore forming subunit Kir6.2, with an IC50 of 22.2 μM. Cibenzoline inhibits IKr and IKs currents with IC50 values of 8.8 μM and 12.3 μM, respectively. Cibenzoline is used in the study of cardiac diseases. In addition, Cibenzoline can induce hypoglycemia.
    Cibenzoline-d<sub>5</sub>
  • HY-15409S2
    Empagliflozin-d6
    Empagliflozin-d6 (BI 10773-d6) is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2.
    Empagliflozin-d<sub>6</sub>
  • HY-B0316S1
    Avobenzone-d3
    Avobenzone-d3 is deuterium labeled Avobenzone. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist.
    Avobenzone-d<sub>3</sub>
  • HY-B2137S
    S-(+)-Ketoprofen-d3
    S-(+)-Ketoprofen-d3 ((S)-Ketoprofen-d3) is deuterium labeled S-(+)-Ketoprofen. S-(+)-Ketoprofen is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively.
    S-(+)-Ketoprofen-d<sub>3</sub>
  • HY-B0268S2
    Enoxacin-d8 hydrate
    Enoxacin-d8 (hydrate) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 μg/ml) and topoisomerase IV (IC50=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing.
    Enoxacin-d<sub>8</sub> hydrate
  • HY-W128255S1
    2-(4,6-Diphenyl-1,3,5-triazin-2-yl)-5-methoxyphenol-d3
    2-(4,6-Diphenyl-1,3,5-triazin-2-yl)-5-methoxyphenol-d3 (2-(4,6-Diphenyl-1,3,5-triazine-2-yl)-5-methoxy-xyphenol-d3) is deuterium labeled 2-(4,6-Diphenyl-1,3,5-triazin-2-yl)-5-methoxyphenol.
    2-(4,6-Diphenyl-1,3,5-triazin-2-yl)-5-methoxyphenol-d<sub>3</sub>
  • HY-B0334S
    Sulbactam-d3
    Sulbactam-d3 (CP45899-d3) is deuterium labeled Sulbactam. Sulbactam (CP45899) is a competitive, irreversible beta-lactamase inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex.
    Sulbactam-d<sub>3</sub>
  • HY-144344S
    Benzyl(2R)-3-N,N-dibenzylamino-2-fluoropropanoate-13C3
    Benzyl(2R)-3-N,N-dibenzylamino-2-fluoropropanoate-13C3 is a 13C-labeled and deuterium labeled Benzyl(2R)-3-N,N-dibenzylamino-2-fluoropropanoate[1].
    Benzyl(2R)-3-N,N-dibenzylamino-2-fluoropropanoate-<sup>13</sup>C<sub>3</sub>
  • HY-144418S
    DL-2-Amino-3-(hydroxy-amino)propionic acid-15N
    DL-2-Amino-3-(hydroxy-amino)propionic acid-15N is a 15N-labeled DL-2-Amino-3-(hydroxy-amino)propionic acid[1].
    DL-2-Amino-3-(hydroxy-amino)propionic acid-<sup>15</sup>N
  • HY-B0121BS2
    Sumatriptan-d5
    Sumatriptan-d5 is deuterated labeled Sumatriptan (HY-B0121B). Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan can be used for migraine headache research.
    Sumatriptan-d<sub>5</sub>
  • HY-W010179S1
    2-Methoxynaphthalene-d2
    2-Methoxynaphthalene-d2 is the deuterium labeled 2-Methoxynaphthalene (HY-W101130). 2-Methoxynaphthalene can be used to investigate the catalytic benefits of delamination, as well as to study alkali metal-mediated manganization (AMMMn) reactions.
    2-Methoxynaphthalene-d<sub>2</sub>
  • HY-W704091
    α-Amino-β-methylaminopropionic acid-d3 hydrochloride
    α-Amino-β-methylaminopropionic acid-d3 hydrochloride is the deuterium labeled α-Amino-β-methylaminopropionic acid. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.
    α-Amino-β-methylaminopropionic acid-d<sub>3</sub> hydrochloride
  • HY-Y1269AS
    Ammonium chloride-d4
    Ammonium chloride-d4 is the deuterium labeled Ammonium chloride. Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor.
    Ammonium chloride-d<sub>4</sub>
  • HY-111372S1
    Finerenone-d5
    Finerenone-d5 (BAY 94-8862-d5) is deuterium labeled Finerenone. Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.
    Finerenone-d<sub>5</sub>
  • HY-14300S2
    Vilanterol-d12
    Vilanterol-d12 (GW642444-d12) is deuterium labeled Vilanterol. Vilanterol (GW642444) is a long-acting β2-adrenoceptor (β2-AR) agonist with 24 h activity. The pEC50s for β2-AR,β1-AR and β3-AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively.
    Vilanterol-d<sub>12</sub>
  • HY-10122S
    Silodosin-d4
    Silodosin-d4 is the deuterium labeled Silodosin. Silodosin (KAD 3213) is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker. Silodosin exhibits high affinity for α1A-AR (Ki=0.036 nM), over 162-fold and 50-fold than for α1B-AR and α1D-AR with Ki values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH[1][3].
    Silodosin-d<sub>4</sub>