2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7664):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-14885S2
    Eliglustat-d15
    Eliglustat-d15 (Genz 99067-d15) is deuterium labeled Eliglustat. Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.
    Eliglustat-d<sub>15</sub>
  • HY-23331S
    4-Methylimidazolidine-2-thione-d3
    4-Methylimidazolidine-2-thione-d3 is deuterium labeled 4-Methylimidazolidine-2-thione.
    4-Methylimidazolidine-2-thione-d<sub>3</sub>
  • HY-W106835S1
    N-(3-Hydroxybenzyl)adenosine-15N,d2
    N-(3-Hydroxybenzyl)adenosine-15N,d2 is 15N and deuterium labeled N-(3-Hydroxybenzyl)adenosine.
    N-(3-Hydroxybenzyl)adenosine-<sup>15</sup>N,d<sub>2</sub>
  • HY-12365S2
    Namodenoson-d5
    Namodenoson-d5 (CF-102-d5) is deuterium labeled Namodenoson. Namodenoson (CF-102) is a selective A3 adenosine receptor (A3AR) agonist (Ki=0.33 nM). Namodenoson displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively.
    Namodenoson-d<sub>5</sub>
  • HY-15307S
    Belumosudil-d7
    Belumosudil-d7 (KD025-d7) is deuterium labeled Belumosudil. Belumosudil (KD025) is a selective inhibitor of ROCK2 with IC50s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties.
    Belumosudil-d<sub>7</sub>
  • HY-B0458AS
    Cefprozil-d4
    Cefprozil-d4 is the deuterium labeled Cefprozi (HY-B0458A). Cefprozil is a second-generation cephalosporin type antibiotic. Cefprozil exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
    Cefprozil-d<sub>4</sub>
  • HY-125033S1
    EIDD-1931-d2
    EIDD-1931-d2 is the deuterium labeled 3,6-Dichloro-2-methoxybenzoic acid.
    EIDD-1931-d<sub>2</sub>
  • HY-14268S3
    Febuxostat-d5
    Febuxostat-d5 (TEI 6720-d5) is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a Ki value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout.
    Febuxostat-d<sub>5</sub>
  • HY-100442S
    Paquinimod-d5
    Paquinimod-d5 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice.
    Paquinimod-d<sub>5</sub>
  • HY-W268109S
    3-Mercaptopentan-2-one-d2
    3-Mercaptopentan-2-one-d2 is deuterated labeled 3-Methylbut-2-ene-1-thiol.
    3-Mercaptopentan-2-one-d<sub>2</sub
  • HY-14656S2
    Diltiazem-d6 hydrochloride
    Diltiazem-d6 (hydrochloride) (CRD-401-d6 (hydrochloride)) is deuterium labeled Diltiazem (hydrochloride). Diltiazem hydrochloride is a Ca2+ influx inhibitor (slow channel blocker or calcium antagonist).
    Diltiazem-d<sub>6</sub> hydrochloride
  • HY-B1204S2
    Histamine-13C5, 15N3
    Histamine-13C5, 15N3 (Ergamine-13C5, 15N3) is the 13C and 15N labeled isotope of Histamine (HY-B1204). Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter.
    Histamine-<sup>13</sup>C<sub>5</sub>, <sup>15</sup>N<sub>3</sub>
  • HY-W700927
    N-Formyl-L-leucine-d3
    N-Formyl-L-leucine-d3 (N-Formyl-S-leucine-d3) is deuterium labeled N-Formyl-L-leucine. N-Formyl-L-leucine is a leucine derivative.
    N-Formyl-L-leucine-d<sub>3</sub>
  • HY-13777S1
    Zoledronic acid-d3
    Zoledronic acid-d3 is the deuterium labeled Zoledronic acid.
    Zoledronic acid-d<sub>3</sub>
  • HY-W719722
    Chloraminophenamide-15N2
    Chloraminophenamide-15N2 is 15N labeled Chloraminophenamide.
    Chloraminophenamide-<sup>15</sup>N<sub>2</sub>
  • HY-138815S
    (S)-N-(1H-Indole-3-acetyl)tryptophan-d4
    (S)-N-(1H-Indole-3-acetyl)tryptophan-d4 is deuterium labeled (S)-N-(1H-Indole-3-acetyl)tryptophan. (S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a Tryptophan derivative that weakly inhibits β-D-glucosidase.
    (S)-N-(1H-Indole-3-acetyl)tryptophan-d<sub>4</sub>
  • HY-132439S
    4-Hydroxy Mepivacaine-d3
    4-Hydroxy Mepivacaine-d3 is the deuterium labeled 4-Hydroxy Mepivacaine[1].
    4-Hydroxy Mepivacaine-d<sub>3</sub>
  • HY-W654127
    Cytarabine-13C3 5'-monophosphate
    Cytarabine-13C3 5'-monophosphate is 13C labeled Cytarabine 5’-monophosphate.
    Cytarabine-<sup>13</sup>C<sub>3</sub> 5'-monophosphate
  • HY-W021040S
    Fludioxonil-13C3
    Fludioxonil-13C3 (CGA-173506-13C3) is 13C labeled Fludioxonil. Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells.
    Fludioxonil-<sup>13</sup>C<sub>3</sub>
  • HY-10574S1
    Rilpivirine-13C6
    Rilpivirine-13C6 (R278474-13C6) is 13C labeled Rilpivirine. Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV.
    Rilpivirine-<sup>13</sup>C<sub>6</sub>