2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7664):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100977S
    Dimethoxycurcumin-d6
    Dimethoxycurcumin-d6 is the deuterium labeled Dimethoxycurcumin (HY-100977). Dimethoxycurcumin is a derivative of Curcumin that has anti-inflammatory and antioxidant activities.
    Dimethoxycurcumin-d<sub>6</sub>
  • HY-32329S
    Setiptiline-d3
    Setiptiline-d3 is the deuterium labeled Setiptiline. Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine[1][2].
    Setiptiline-d<sub>3</sub>
  • HY-W015778S
    2-Methoxy-5-methylphenol-d3
    2-Methoxy-5-methylphenol-d3 is deuterated labeled 2,3-Diethyl-5-methylpyrazine.
    2-Methoxy-5-methylphenol-d<sub>3</sub>
  • HY-173102S
    LQEEIDAVL(Pro-13C5,15N)NK TFA
    LQEEIDAVL(Pro-13C5,15N)NK TFA is the 13C- and 15N-labeled LQEEIDAVL(Pro)NK TFA.
    LQEEIDAVL(Pro-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N)NK TFA
  • HY-W654335
    Rivastigmine-d4 tartrate
    Rivastigmine-d4 (tartrate) is deuterium labeled Rivastigmine (tartrate). Rivastigmine tartrate (ENA 713; SDZ-ENA 713) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM, 4.15 μM, respectively. Rivastigmine tartrate can pass the blood brain barrier (BBB). Rivastigmine tartrate is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.
    Rivastigmine-d<sub>4</sub> tartrate
  • HY-136081AS
    Hexamidine-d12 dihydrochloride
    Hexamidine-d12 (dihydrochloride) is the deuterium labeled Hexamidine dihydrochloride[1].
    Hexamidine-d<sub>12</sub> dihydrochloride
  • HY-10019S2
    Varenicline-13C,15N
    Varenicline-13C15N (CP 526555-13C15N) is 13C and 15N labeled Varenicline. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation.
    Varenicline-<sup>13</sup>C<sub>,<sup>15</sup>N<sub>
  • HY-W144021S
    1-Hexen-3-one-d3
    1-Hexen-3-one-d3 is deuterated labeled Phenethyl acetate.
    1-Hexen-3-one-d<sub>3</sub>
  • HY-W653999
    Glycodeoxycholic acid-d5
    Glycodeoxycholic acid-d5 is deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.
    Glycodeoxycholic acid-d<sub>5</sub>
  • HY-W654073
    Bifenthrin-d5
    Bifenthrin-d5 ((±)-Bifethi-d5) is deuterium labeled Bifenthrin.
    Bifenthrin-d<sub>5</sub>
  • HY-10218S1
    Everolimus-13C2,d4
    Everolimus-13C2,d4 (RAD001-13C2,d4) is 13C labeled Everolimus. Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities.
    Everolimus-<sup>13</sup>C<sub>2</sub>,d<sub>4</sub>
  • HY-157056S
    5α-Estran-3β-ol-17-one-d3
    5α-Estran-3β-ol-17-one-d3 is deuterium-labeled 5α-Estran-3β-ol-17-one.
    5α-Estran-3β-ol-17-one-d<sub>3</sub>
  • HY-14773S3
    Mirabegron-d5
    Mirabegron-d5 (YM178-d5) is deuterium labeled Mirabegron. Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
    Mirabegron-d<sub>5</sub>
  • HY-W440436S
    2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d4
    2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d4 is deuterium labeled 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol.
    2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d<sub>4</sub>
  • HY-14149S
    Cisapride-d6
    Cisapride-d6 (R51619-d6) is deuterium labeled Cisapride. Cisapride (R 51619) is an orally active 5-HT4 receptor agonist with an EC50 value of 140 nM. Cisapride is a hERG blocker with an IC50 value of 9.4 nM. Cisapride is a gastroprokinetic agent that stimulates gastrointestinal motor activity.
    Cisapride-d<sub>6</sub>
  • HY-165678S
    (±)-10-Hydroxy-12(Z)-Octadecenoic acid-d5
    (±)-10-Hydroxy-12(Z)-Octadecenoic acid-d5 (10-Hydoxy-cis-12-Octadeceoic Acid-d5) is deuterium labeled (±)-10-Hydroxy-12(Z)-Octadecenoic acid.
    (±)-10-Hydroxy-12(Z)-Octadecenoic acid-d<sub>5</sub>
  • HY-W742014
    Hydroxymethyl clenbuterol-d6
    Hydroxymethyl clenbuterol-d6 is deuterium labeled Hydroxymethyl Clenbuterol.
    Hydroxymethyl clenbuterol-d<sub>6</sub>
  • HY-W722289S
    (rac)-Metolachlor metabolite CGA 50267-d3
    (rac)-Metolachlor metabolite CGA 50267-d3 (N-(2-(Ethyl-2,2,2-d3)-6-methylphenyl)-2-aminopropanoic acid) is deuterium labeled (2-Ethyl-6-methylphenyl)alanine.
    (rac)-Metolachlor metabolite CGA 50267-d<sub>3</sub>
  • HY-173107S
    Haemoglobin HbA0 (a2b2), U-15N
    Haemoglobin HbA0 (a2b2), U-15N is the 15N-labeled Haemoglobin Haemoglobin HbA0 (a2b2), U.
    Haemoglobin HbA0 (a2b2), U-<sup>15</sup>N
  • HY-107333S
    Cinoxate-d3
    Cinoxate-d3 is deuterium labeled Cinoxate. Cinoxate is a hypertrophic peroxisome proliferator activating receptor γ (PPARγ) agonist with Ki value of 18.0 μM. Cinoxate can be used to study obesity.
    Cinoxate-d<sub>3</sub>