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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9620):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-116429S
    Maresin 1-d5
    Maresin 1-d5 is the deuterium labeled Maresin 1. Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion. Maresin 1 possesses anti-inflammatory activity.
    Maresin 1-d<sub>5</sub>
  • HY-W719170
    Sodium (S)-2-(hydroxymethyl)propanoate-3,3,3-d3
    Sodium (S)-2-(hydroxymethyl)propanoate-3,3,3-d3 is the deuterium labeled Sodium (S)-2-(hydroxymethyl)propanoate.
    Sodium (S)-2-(hydroxymethyl)propanoate-3,3,3-d<sub>3</sub>
  • HY-133671S
    Monooctyl phthalate-d4
    Monooctyl phthalate-d4 (Mono-n-octyl phthalate-d4) is a deuterium labeled Monooctyl phthalate (HY-133671). Monooctyl phthalate (Mono-n-octyl phthalate) exhibits antimycobacterial activity with a MIC of 20 μg/mL.
    Monooctyl phthalate-d<sub>4</sub>
  • HY-B1834S1
    Megestrol-d5
    Megestrol-d5 is the deuterium labeled Megestrol. Megestrol is a synthetic progestin and used for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis.
    Megestrol-d<sub>5</sub>
  • HY-N2026S
    Propylparaben-d7
    Propylparaben-d7 (Propyl parahydroxybenzoate-d7) is the deuterium labeled Propylparaben (HY-N2026). Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben disrupts antral follicle growth and steroidogenic function by altering the cell-cycle, apoptosis, and steroidogenesis pathways. Propylparaben also decreases sperm number and motile activity in rats.
    Propylparaben-d<sub>7</sub>
  • HY-109025AS
    Baloxavir-d5
    Baloxavir-d5 is deuterium labeled Baloxavir. Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity.
    Baloxavir-d<sub>5</sub>
  • HY-110018S
    N-Arachidonyldopamine-d8
    N-Arachidonyldopamine-d8 is the deuterium labeled N-Arachidonyldopamine.
    N-Arachidonyldopamine-d<sub>8</sub>
  • HY-142641S
    4-Hydroxy triamterene sulfate-d4 sodium
    4-Hydroxy triamterene sulfate-d4 (sodium) is the deuterium labeled 4-Hydroxy triamterene sulfate sodium.
    4-Hydroxy triamterene sulfate-d<sub>4</sub> sodium
  • HY-Y1804S
    D-Lysine-d4 monohydrochloride
    D-Lysine-d4 (monohydrochloride) is the deuterium labeled D-Lysine. D-Lysine monohydrochloride is an Lysine stereoisomer which can be used as a component of surfactants.
    D-Lysine-d<sub>4</sub> monohydrochloride
  • HY-Y0350S
    1,4-Dibromobutane-2,2,3,3-d4
    1,4-Dibromobutane-2,2,3,3-d4 is the deuterium labeled 1,4-Dibromobutane.
    1,4-Dibromobutane-2,2,3,3-d<sub>4</sub>
  • HY-B0194AS
    Tizanidine-d4 hydrochloride
    Tizanidine-d4 (hydrochloride) is deuterium labeled Tizanidine (hydrochloride).
    Tizanidine-d<sub>4</sub> hydrochloride
  • HY-B0495S
    Lamotrigine-13C3,d3
    Lamotrigine-13C3,d3 is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy,?focal seizure, et al.
    Lamotrigine-<sup>13</sup>C<sub>3</sub>,d<sub>3</sub>
  • HY-10493S
    Cobicistat-d8
    Cobicistat-d8 (GS-9350-d8) is a deuterated version of Cobicistat (HY-10493). Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) with IC50 values of 30-285 nM. Cobicistat is a pharmacokinetic enhancer that enhances the absorption of anti-HIV active molecules.
    Cobicistat-d<sub>8</sub>
  • HY-138616S2
    dGTP-15N5,d14 dilithium
    dGTP-15N5,d14 (2'-Deoxyguanosine-5'-triphosphate-15N5,d14) dilithium is deuterium and 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
    dGTP-<sup>15</sup>N<sub>5</sub>,d<sub>14</sub> dilithium
  • HY-W744986
    L-2-Hydroxyglutaric acid-d5 disodium
    L-2-Hydroxyglutaric acid-d5 disodium ((2S)-2-Hydroxyglutaric acid-d5 disodium) is the deuterium labeled L-2-Hydroxyglutaric acid disodium (HY-W015114). L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively.
    L-2-Hydroxyglutaric acid-d<sub>5</sub> disodium
  • HY-79490S
    Ac-Exatecan-d5
    99.93%
    Ac-Exatecan-d5 is the deuterium labeled Ac-Exatecan (HY-79490).
    Ac-Exatecan-d<sub>5</sub>
  • HY-W699547
    2-(3-Chlorophenyl)-1-(pyridin-3-yl-d4)ethan-1-one
    2-(3-Chlorophenyl)-1-(pyridin-3-yl-d4)ethan-1-one is the deuterium labeled 2-(3-Chlorophenyl)-1-(pyridin-3-yl)ethan-1-one (HY-W699543).
    2-(3-Chlorophenyl)-1-(pyridin-3-yl-d<sub>4</sub>)ethan-1-one
  • HY-B0732S
    Itopride-d6 hydrochloride
    Itopride-d6 (hydrochloride) is deuterium labeled Itopride (hydrochloride). Itopride hydrochloride (HSR803), a gastroprokinetic Benzamide (HY-Z0283) derivative, is an inhibitor of acetylcholinesterase (AChE) and dopamine D2 receptor.
    Itopride-d<sub>6</sub> hydrochloride
  • HY-142249S
    Brexpiprazole-d8 hydrochloride
    Brexpiprazole-d8 (hydrochloride) is the deuterium labeled Brexpiprazole hydrochloride.
    Brexpiprazole-d<sub>8</sub> hydrochloride
  • HY-U00462S
    D-Mannoheptulose-13C
    D-Mannoheptulose-13C is the 13C labeled D-Mannoheptulose (HY-U00462). D-Mannoheptulose is a 7-carbon keto sugar found in avocado. D-mannoheptulose is a specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes. D-Mannoheptulose can block insulin release and utilization of carbohydrate in rat. D-Mannoheptulose has various functions as anti-oxidants, anticancer effects and energy sources.
    D-Mannoheptulose-<sup>13</sup>C