2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7666):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0637S2
    Bezafibrate-13C6
    Bezafibrate-13C6 (BM15075-13C6) is 13C labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.
    Bezafibrate-<sup>13</sup>C<sub>6</sub>
  • HY-B0506S1
    Nadifloxacin-d5
    Nadifloxacin-d5 (OPC7251-d5) is deuterium labeled Nadifloxacin. Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.
    Nadifloxacin-d<sub>5</sub>
  • HY-13502AS1
    Mitoxantrone-d8 hydrochloride
    Mitoxantrone-d8 (hydrochloride) (Mitozantrone-d8 (hydrochloride)) is deuterium labeled Mitoxantrone (dihydrochloride). Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.
    Mitoxantrone-d<sub>8</sub> hydrochloride
  • HY-165657S
    EOP (t18:0/28:0/18:2)-d11
    EOP (t18:0/28:0/18:2)-d11 is deuterium labeled EOP (t18:0/28:0/18:2).
    EOP (t18:0/28:0/18:2)-d<sub>11</sub>
  • HY-B0426AS
    Olopatadine-d3 hydrochloride
    Olopatadine-d3 (hydrochloride) (ALO4943A-d3) is the deuterium labeled Olopatadine hydrochloride. Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis[1][2].
    Olopatadine-d<sub>3</sub> hydrochloride
  • HY-12717AS
    Phentolamine-d4 hydrochloride
    Phentolamine-d4 (hydrochloride) is the deuterium labeled Phentolamine hydrochloride. Phentolamine hydrochloride is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptor that expands blood vessels to reduce peripheral vascular resistance. Phentolamine hydrochloride can be used for the research of pheochromocytoma-related hypertension, heart failure and erectile dysfunction[1][2][3].
    Phentolamine-d<sub>4</sub> hydrochloride
  • HY-W725649
    Chlorfenapyr-d7
    Chlorfenapyr-d7 is deuterium labeled Chlorfenapyr.
    Chlorfenapyr-d<sub>7</sub>
  • HY-W744124
    4'-Fluoroacetophenone-d4
    4'-Fluoroacetophenone-d4 (1-(4-Fluorophenyl)ethan-1-one-d4) is deuterium labeled 4'-Fluoroacetophenone. 4'-Fluoroacetophenone (1-(4-Fluorophenyl)ethan-1-one) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    4'-Fluoroacetophenone-d<sub>4</sub>
  • HY-D0205AS1
    Carbocisteine-13C3-1
    Carbocisteine-13C3-1 (Carbocysteine-13C3-1) is 13C labeled Carbocisteine. Carbocisteine is an orally active mucolytic agent. Carbocisteine attenuates the phosphorylation of NF-κB p65 and ERK1/2. Carbocisteine modulates Nrf2/HO-1 and NFκB interplay. Carbocisteine inhibits Apoptosis. Carbocisteine is used in chronic obstructive pulmonary disease (COPD) research.
    Carbocisteine-<sup>13</sup>C3-1
  • HY-W014389S
    9,9-Dimethyl-9H-xanthene-d2
    9,9-Dimethyl-9H-xanthene-d2 is the deuterium labeled 9,9-Dimethyl-9H-xanthene (HY-W014389).
    9,9-Dimethyl-9H-xanthene-d<sub>2</sub>
  • HY-150194S
    Fructose-glutamic acid-13C6
    Fructose-glutamic acid-13C6 is 13C labeled 2-Ethyl-3,5-dimethylpyrazine,mixtureofisomers.
    Fructose-glutamic acid-<sup>13</sup>C<sub>6</sub>
  • HY-W710753
    D,L-Sulforaphane glutathione-d5
    D,L-Sulforaphane glutathione-d5 (DL-SFN-GSH-d5) is deuterium labeled DL-Sulforaphane glutathione. DL-Sulforaphane glutathione (DL-SFN-GSH) is a metabolite of Sulforaphane (HY-13755) in rat plasma.
    D,L-Sulforaphane glutathione-d<sub>5</sub>
  • HY-10181S1
    Dasatinib-d4
    Dasatinib-d4 (BMS-354825-d4) is deuterium labeled Dasatinib. Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib also induces apoptosis and autophagy.
    Dasatinib-d<sub>4</sub>
  • HY-B1396S3
    Nefazodone-d4 hydrochloride
    Nefazodone-d4 (hydrochloride) (BMY-13754-d4) is deuterium labeled Nefazodone (hydrochloride). Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A (Ki=5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake (IC50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity.
    Nefazodone-d<sub>4</sub> hydrochloride
  • HY-Y0496S
    1,4-Dichlorobenzene-d4
    		≥99.0%
    1,4-Dichlorobenzene-d4 is the deuterium labeled 1,4-Dichlorobenzene[1]. 1,4-Dichlorobenzene is used as an intermediate product in the manufacture of pigments, pesticides and disinfectants. 1,4-Dichlorobenzene is also employed as a moth control agent[2].
    1,4-Dichlorobenzene-d<sub>4</sub>
  • HY-N0367S
    Trans-Anethole-d3
    Trans-Anethole-d3 is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption.
    Trans-Anethole-d<sub>3</sub>
  • HY-16774S
    Vericiguat-d3 hydrochloride
    		99.81%
    Vericiguat-d3 (BAY1021189-d3) hydrochloride is a deuterated Vericiguat with tracer functionality. Vericiguat is an orally available stimulator of guanylate cyclase.
    Vericiguat-d<sub>3</sub> hydrochloride
  • HY-152051S
    Mabuterol-d9 hydrochloride
    Mabuterol-d9 (hydrochloride) is deuterium labeled Mabuterol (hydrochloride). Mabuterol hydrochloride is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB.
    Mabuterol-d<sub>9</sub> hydrochloride
  • HY-W041300S
    p-Tolylpinacolboronate-d3
    p-Tolylpinacolboronate-d3 (p-Tolylboronic acid pinacol ester-d3) is the deuterium labeled 4,4,5,5-Tetramethyl-2-(p-tolyl)-1,3,2-dioxaborolane (HY-N0350).
    p-Tolylpinacolboronate-d<sub>3</sub>
  • HY-138687S
    Nirmatrelvir-d9
    		99.93%
    Nirmatrelvir-d9 (PF-07321332-d9) is the deuterium labeled Nirmatrelvir (HY-138687).
    Nirmatrelvir-</sub>d<sub>9</sub>