Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (2)

Isotope-Labeled Compounds Related Products (9620):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-139938S

(±)11(12)-EET methyl ester-d₁₁
(±)11(12)-EET-d₁₁ methyl ester is the deuterium labeled (±)11(12)-EET methyl ester.

HY-150716S

Iodopropamine-d₃
Iodopropamine-d₃ is the deuterium labeled Iodopropamine.

HY-W342261S

1,2,3,5-Tetramethylbenzene-d₁₄
1,2,3,5-Tetramethylbenzene-d₁₄ is the deuterium labeled 1,2,3,5-Tetramethylbenzene.

HY-W778300

Sodium 2-cyanoacetate-¹³C₂
Sodium 2-cyanoacetate-¹³C₂ (Sodium cyanoacetate-¹³C₂) is the ¹³C-labeled Sodium 2-cyanoacetate (HY-W129503).

HY-B0380S1

Trimebutine-d₅ fumarate
Trimebutine-d₅ fumarate is deuterium labeled Trimebutine fumarate. Trimebutine fumarate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. Trimebutine fumarate inhibits L-type Ca²⁺ channels and large-conductance calcium-activated potassium channels (BK_Ca channels), thereby inhibiting extracellular calcium influx and potassium ion efflux. Trimebutine fumarate also targets Toll-like receptors, inhibits Toll-like receptor 2/4/7/8/9 signals, and inhibits LPS-induced IRAK1 activation, as well as ERK1/2, JNK and NF-κB activation, thereby exerting anti-inflammatory effects. Trimebutine fumarate also induces tumor cell apoptosis by inhibiting the AKT/ERK pathway. Trimebutine fumarate also inhibits excessive contraction of smooth muscle and can be used in the study of gastrointestinal disorders such as irritable bowel syndrome (IBS).

HY-Y0503S

Methyltriphenylphosphonium iodide-d₃
Methyltriphenylphosphonium iodide-d₃ is the deuterium labeled Methyltriphenylphosphonium iodide.

HY-100659S

Dihydrodiol-Ibrutinib-d₅
Dihydrodiol-Ibrutinib-d5 is the deuterium labeled Dihydrodiol-Ibrutinib (HY-100659). Dihydrodiol-Ibrutinib is a dihydrodiol active metabolite of Ibrutinib (HY-10997), has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib.

HY-139474S1

N-Acetyl-S-(carbamoylethyl)-L-cysteine-d₄
N-Acetyl-S-(carbamoylethyl)-L-cysteine-d₄ is the deuterium labeled N-Acetyl-S-(carbamoylethyl)-L-cysteine.

HY-W706160

Di-p-tolyl Phosphorochloridate-d₁₄
Di-p-tolyl Phosphorochloridate-d₁₄ is the deuterium labeled Di-p-tolyl phosphorochloridate (HY-W706159).

HY-151909S

Endothall-3,4,4,5,5,6 H2O-d₆
Endothall-3,4,4,5,5,6 H2O-d₆ is the deuterium labeled 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid hydrate (HY-W714211).

HY-15731S1

Estetrol-d₄ (Major)
Estetrol-d₄ (Major) is the deuterium labeled Estetrol (HY-15731). Estetrol, an orally active estrogen synthesized exclusively during pregnancy by the human fetal liver, is a selective nuclear estrogen receptor modulator. Estetrol binds ERα as well as ERβ (with a fourfold lower affinity). Estetrol increases eNOS expression/activity and NO synthesis in endothelial cells. Estetrol exerts estrogenic actions on the endometrium or the central nervous system but presents antagonistic effects on the breast. Estetrol can be used in contraception and menopausal hormone research.

HY-143797S

Almotriptan-d₆ maleate
Almotriptan-d₆ (maleate) is the deuterium labeled Almotriptan maleate.

HY-152048S

Methomyl-d₃
Methomyl-d₃ is a deuterium labeled compound.

HY-146868S

1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine-d₅ sodium
1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-W770914

Stearoyl-L-carnitine chloride-¹³C₃
Stearoyl-L-carnitine chloride-¹³C₃ is the ¹³C-labeled Stearoyl-L-carnitine chloride (HY-130466). Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.

HY-W099570S

Stearate-d₃₅ sodium
Stearate-d₃₅ (sodium) is the deuterium labeled Stearate.

HY-W779236

Ethyl Propargylate-¹³C₃
Ethyl Propargylate-¹³C₃ (Propiolic acid ethyl ester-¹³C₃) is the ¹³C-labeled Ethyl propiolate (HY-Y0871).

HY-144193S

MCPP methyl ester-d₃
MCPP methyl ester-d₃ is the deuterium labeled MCPP methyl ester.

HY-132947S

Heptadecanoyl-L-carnitine-d₃ chloride
Heptadecanoyl-L-carnitine-d₃ (chloride) is the deuterium labeled Heptadecanoyl-L-carnitine chloride.

HY-13011S

Alectinib-d₈
Alectinib-d₈ is the deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC₅₀ of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC₅₀s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

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