2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9620):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-23188
    Loratadine-d5-1
    Loratadine-d5-1 is a deuterated labeled Loratadine (HY-17043). Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
    Loratadine-d<sub>5</sub>-1
  • HY-13955S2
    Telmisartan-13C,d3
    Telmisartan-13C,d3 is the 13C- and deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM.
    Telmisartan-<sup>13</sup>C,d<sub>3</sub>
  • HY-W718796
    DL-Serine-15N
    DL-Serine-15N is 15N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
    DL-Serine-<sup>15</sup>N
  • HY-B2020S
    Fenuron-d5
    Fenuron-d5 is the deuterium labeled Fenuron. Fenuron is a phenyl urea-based widely used herbicide.
    Fenuron-d<sub>5</sub>
  • HY-19489S3
    (±)-Levomepromazine-d3
    (±)-Levomepromazine-d3 is deuterium labeled (±)-Levomepromazine.
    (±)-Levomepromazine-d<sub>3</sub>
  • HY-10581AS
    Gatifloxacin-d3 hydrochloride
    Gatifloxacin-d3 (hydrochloride) is the deuterium labeled Gatifloxacin (hydrochloride). Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
    Gatifloxacin-d<sub>3</sub> hydrochloride
  • HY-41680S
    4-Aminobenzonitrile-d4
    4-Aminobenzonitrile-d4 is the deuterium labeled 4-Aminobenzonitrile[1].
    4-Aminobenzonitrile-d<sub>4</sub>
  • HY-127035S4
    Tristearin-d9
    Tristearin-d9 is the deuterium labeled Tristearin.
    Tristearin-d<sub>9</sub>
  • HY-109506S5
    DPPC-d13
    DPPC-d13 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
    DPPC-d<sub>13</sub>
  • HY-W749302
    O-tert-Butyl-dimethylsilyl curcumin-d6
    O-tert-Butyl-dimethylsilyl curcumin-d6 is the deuterium labeled O-tert-Butyl-dimethylsilyl curcumin.
    O-tert-Butyl-dimethylsilyl curcumin-d<sub>6</sub>
  • HY-B0380S2
    Trimebutine-d3 hydrochloride
    Trimebutine-d3 hydrochloride is deuterium labeled Trimebutine hydrochloride. Trimebutine hydrochloride is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. Trimebutine hydrochloride inhibits L-type Ca2+ channels and large-conductance calcium-activated potassium channels (BKCa channels), thereby inhibiting extracellular calcium influx and potassium ion efflux. Trimebutine hydrochloride also targets Toll-like receptors, inhibits Toll-like receptor 2/4/7/8/9 signals, and inhibits LPS-induced IRAK1 activation, as well as ERK1/2, JNK and NF-κB activation, thereby exerting anti-inflammatory effects. Trimebutine hydrochloride also induces tumor cell apoptosis by inhibiting the AKT/ERK pathway. Trimebutine hydrochloride also inhibits excessive contraction of smooth muscle and can be used in the study of gastrointestinal disorders such as irritable bowel syndrome (IBS).
    Trimebutine-d<sub>3</sub> hydrochloride
  • HY-W131351S
    N-heptadecane-d36
    N-heptadecane-d36 is the deuterium labeled N-heptadecane.
    N-heptadecane-d<sub>36</sub>
  • HY-143817S
    Clopidogrel-d3 hydrochloride
    Clopidogrel-d3 (hydrochloride) is the deuterium labeled Clopidogrel hydrochloride.
    Clopidogrel-d<sub>3</sub> hydrochloride
  • HY-144143S
    N-Desmethyl Olopatadine-d3 hydrochloride
    N-Desmethyl Olopatadine-d3 (hydrochloride) is the deuterium labeled N-Desmethyl Olopatadine hydrochloride.
    N-Desmethyl Olopatadine-d<sub>3</sub> hydrochloride
  • HY-N0215S6
    DL-Phenylalanine-d5 hydrochloride
    DL-Phenylalanine-d5 (hydrochloride) is the deuterium labeled DL-Phenylalanine hydrochloride. L-Phenylalanine hydrochloride is an essential amino acid isolated from Escherichia coli. L-Phenylalanine hydrochloride is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine hydrochloride is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine hydrochloride is widely used in the production of food flavors and pharmaceuticals.
    DL-Phenylalanine-d<sub>5</sub> hydrochloride
  • HY-B0369AS
    Orphenadrine-d3 citrate
    Orphenadrine-d3 (citrate) is the deuterium labeled Orphenadrine citrate. Orphenadrine citrate is a NMDA receptor antagonist with Ki of 6.0 +/- 0.7 μM, HERG potassium channel blocker.
    Orphenadrine-d<sub>3</sub> citrate
  • HY-146866S
    1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d5 sodium
    1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d5 (sodium) is deuterium labeled 1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine (sodium).
    1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d<sub>5</sub> sodium
  • HY-15494S1
    Picropodophyllin-d6
    Picropodophyllin-d6 (AXL1717-d6) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
    Picropodophyllin-d<sub>6</sub>
  • HY-W707400
    Ethane-1,2-diyl-d4 dibenzoate
    Ethane-1,2-diyl-d4 dibenzoate is the deuterium labeled Ethylene Glycol Dibenzoate (HY-W103900).
    Ethane-1,2-diyl-d<sub>4</sub> dibenzoate
  • HY-W726231
    4-Methylsyringol-d6
    4-Methylsyringol-d6 is the deuterium labeled 4-Methylsyringol (HY-W100715). 4-Methylsyringol is a natural product that can be isolated from hardwood.
    4-Methylsyringol-d<sub>6</sub>