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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9620):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W744029
    Clothiapine-d8
    Clothiapine-d8 is the deuterium labeled Clothiapine (HY-117083). Clothiapine, an atypical antipsychotic agent, shares with clozapine its strong antiserotonergic properties.
    Clothiapine-d<sub>8</sub>
  • HY-143789S
    Perindopril-d4
    Perindopril-d4 is the deuterium labeled Perindopril.
    Perindopril-d<sub>4</sub>
  • HY-13238S1
    Dolutegravir-d3
    99.64%
    Dolutegravir-d3 is the deuterium labeled Dolutegravir. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM).
    Dolutegravir-d<sub>3</sub>
  • HY-W004289S
    Methyl pentadecanoate-d29
    Methyl pentadecanoate-d29 is the deuterium labeled Methyl pentadecanoate.
    Methyl pentadecanoate-d<sub>29</sub>
  • HY-165668S
    Pitavastatin lactone-d4
    Pitavastatin lactone-d4 (6S-((E)-2-(2-Cyclopropyl-4-(4-fluorophenyl-2,3,5,6-d4)quinolin-3-yl)vinyl)-4R-hydroxytetrahydro-2H-pyran-2-one) is deuterium labeled Pitavastatin lactone.
    Pitavastatin lactone-d<sub>4</sub>
  • HY-P10846
    HYNIC-CTP
    HYNIC-CTP is a conjugate of HYNIC and CTP (cardiac-targeting peptide). HYNIC-CTP can bind with the radionuclide 99mTc through HYNIC acting as a chelator, forming 99mTc-HYNIC-CTP. 99mTc-HYNIC-CTP is specifically taken up by the heart and used for cardiac imaging, thereby facilitating research into heart diseases.
    HYNIC-CTP
  • HY-N7092S7
    D-Fructose-6-13C
    ≥98.0%
    D-Fructose-6-13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
    D-Fructose-6-<sup>13</sup>C
  • HY-N0210S9
    D-Galactose-d2
    D-Galactose-d2 is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
    D-Galactose-d<sub>2</sub>
  • HY-B1732S1
    DL-3-Phenylalanine-13C
    DL-3-Phenylalanine-13C is the 13C labeled DL-3-Phenylalanine.
    DL-3-Phenylalanine-<sup>13</sup>C
  • HY-158994S
    MEGDSRGG-(Ala-13C3,15N)-GGEA-(Leu-13C6,15N)-DPESAASSLSGAS TFA
    MEGDSRGG-(Ala-13C3,15N)-GGEA-(Leu-13C6,15N)-DPESAASSLSGAS TFA is a 13C- and 15N-labeled peptide containing 13C3,15N-labeled alanine (Ala) and 13C6,15N-labeled leucine (Leu).
    MEGDSRGG-(Ala-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N)-GGEA-(Leu-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N)-DPESAASSLSGAS TFA
  • HY-B0726S1
    Pilocarpine-d5 hydrochloride
    Pilocarpine-d5 hydrochloride is deuterated labeled Pilocarpine hydrochloride (HY-B0726). Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    Pilocarpine-d<sub>5</sub> hydrochloride
  • HY-119695AS1
    Simvastatin acid-d9 ammonium
    Simvastatin acid-d9 ammonium is deuterated labeled Simvastatin acid ammonium (HY-119695A). Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
    Simvastatin acid-d<sub>9</sub> ammonium
  • HY-115340S
    Decanoic acid-d19 sodium
    Decanoic acid-d19 (sodium) is the deuterium labeled Decanoic acid.
    Decanoic acid-d<sub>19</sub> sodium
  • HY-W707539
    Carisbamate-d215N
    Carisbamate-d2,-15N (RWJ-333369-d2,-15N) is the deuterium labeled Carisbamate (HY-14948). Carisbamate (RWJ-333369) is an orally active neuromodulator. Carisbamate prevents the development and production of epilep-like discharges and has a neuroprotective effect after in vitro epilepticus-like injury. Carisbamate has good antiepileptic activity in genetic models of generalized and nonconvulsive epilepsy.
    Carisbamate-d<sub>2</sub,-<sup>15</sup>N
  • HY-146945S
    Arachidonoyl LPA-d5
    Arachidonoyl LPA-d5 is deuterium labeled Arachidonoyl LPA.
    Arachidonoyl LPA-d<sub>5</sub>
  • HY-12773AS2
    5-Hydroxy Propafenone-d6 hydrochloride
    5-Hydroxy Propafenone-d6 hydrochloride is deuterated labeled 5-Hydroxy Propafenone.
    5-Hydroxy Propafenone-d<sub>6</sub> hydrochloride
  • HY-Y0123S1
    DL-Tyrosine-d7
    DL-Tyrosine-d7 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine).
    DL-Tyrosine-d<sub>7</sub>
  • HY-W778954
    2,2-Dimethyl-1,3-dioxolane-4-methanol-13C3
    2,2-Dimethyl-1,3-dioxolane-4-methanol-13C3 ((2,2-Dimethyl-[1,3] dioxane-4-yl)-methanol-13C3) is the 13C-labeled 2,2-Dimethyl-1,3-dioxolane-4-methanol (HY-Y1372).
    2,2-Dimethyl-1,3-dioxolane-4-methanol-<sup>13</sup>C<sub>3</sub>
  • HY-W702292
    (R)-(+)-Verapamil-d6 hydrochloride
    (R)-(+)-Verapamil-d6 (hydrochloride) is deuterium labeled (R)-Verapamil (hydrochloride). (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents.
    (R)-(+)-Verapamil-d<sub>6</sub> hydrochloride
  • HY-150981S
    1,2-O-Isopropylidene-a-D-glucofuranuronic-6-13C acid, γ-lactone
    1,2-O-Isopropylidene-a-D-glucofuranuronic-6-13C acid, γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid, γ-lactone.
    1,2-O-Isopropylidene-a-D-glucofuranuronic-6-<sup>13</sup>C acid, γ-lactone