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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9620):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0462S
    Azelastine-13C,d3 hydrochloride
    Azelastine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Azelastine hydrochloride. Azelastine-13C,d3 (hydrochloride), an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine-13C,d3 (hydrochloride) can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2.
    Azelastine-<sup>13</sup>C,d<sub>3</sub> hydrochloride
  • HY-115415S
    1,2-Distearoyl-sn-glycero-3-phosphate-d70 sodium
    1,2-Distearoyl-sn-glycero-3-phosphate-d70 (sodium) is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphate.
    1,2-Distearoyl-sn-glycero-3-phosphate-d<sub>70</sub> sodium
  • HY-W393970S
    2′-Deoxyguanosine 5′-monophosphate-15N5,d12 dilithium
    2′-Deoxyguanosine 5′-monophosphate-15N5,d12 (5'-Deoxyguanylic acid-15N5,d12) dilithium is deuterium and 15N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
    2′-Deoxyguanosine 5′-monophosphate-<sup>15</sup>N<sub>5</sub>,d<sub>12</sub> dilithium
  • HY-W295339S
    N-Desmethyl venlafaxine-d3
    N-Desmethyl venlafaxine-d3 is a deuterium labeled compound.
    N-Desmethyl venlafaxine-d<sub>3</sub>
  • HY-139965S
    4-hydroxy Nonenal Glutathione-d3 TFA
    4-hydroxy Nonenal Glutathione-d3 (TFA) is the deuterium labeled 4-hydroxy Nonenal Glutathione (TFA).
    4-hydroxy Nonenal Glutathione-d<sub>3</sub> TFA
  • HY-W708304
    Asulam-d3
    Asulam-d3 is the deuterium labeled Asulam (HY-B1838). Asulam is a herbicide with control activity against wild oats. Asulam can be used for bulb production in spinach, tulips, daffodils and lilies. Maximum residue limits (MRLs) for Asulam were evaluated in spinach. The review of Asulam took into account its endocrine disrupting properties.
    Asulam-d<sub>3</sub>
  • HY-W009762S5
    L-Lysine-15N2,d9 dihydrochloride
    L-Lysine-15N2,d9 (dihydrochloride) is a 15N-labeled and deuterium labeled L-Lysine dihydrochloride.
    L-Lysine-<sup>15</sup>N<sub>2</sub>,d<sub>9</sub> dihydrochloride
  • HY-143924S
    Belinostat acid-d5
    Belinostat acid-d5 is the deuterium labeled Belinostat acid.
    Belinostat acid-d<sub>5</sub>
  • HY-B1888AS
    Bromfenac-d4 sodium
    Bromfenac-d4 (sodium) is deuterium labeled Bromfenac (sodium). Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium is a brominated non-steroidal anti-inflammatory/analgesic agent (NSAID), and it is commonly used for the research of postoperative inflammation and pain following cataract surgery, and pseudophakic cystoid macular edema (CME).
    Bromfenac-d<sub>4</sub> sodium
  • HY-W017443S4
    L-Asparagine-1,2,3,4-13C4 monohydrate
    L-Asparagine-1,2,3,4-13C4 monohydrate is the 13C labeled labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine-1,2,3,4-<sup>13</sup>C<sub>4</sub> monohydrate
  • HY-Y0055S
    Phenothiazine-d8
    99.0%
    Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases.
    Phenothiazine-d<sub>8</sub>
  • HY-W765261
    Eprinomectin B1a-13C,d3
    Eprinomectin B1a-13C,d3 is the deuterium and 13C labeled Eprinomectin B1a (HY-N8483). Eprinomectin B1a is a Eprinomectin (HY-12643) metabolite (an antiparasitic compound).
    Eprinomectin B1a-<sup>13</sup>C,d<sub>3</sub>
  • HY-W029450S
    Tetrahydropyrimidine-2(1H)-thione-d6
    Tetrahydropyrimidine-2(1H)-thione-d6 is the deuterium labeled Tetrahydropyrimidine-2(1H)-thione.
    Tetrahydropyrimidine-2(1H)-thione-d<sub>6</sub>
  • HY-B0539S4
    Desloratadine-d4 hydrobromide
    Desloratadine-d4 hydrobromide is deuterated labeled Desloratadine (HY-B0539). Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities.
    Desloratadine-d<sub>4</sub> hydrobromide
  • HY-W040206S
    Diflufenican-d3
    Diflufenican-d3 is the deuterium labeled Diflufenican. Diflufenican is a contact, selective herbicide used to specifically control some broad leaved weeds.
    Diflufenican-d<sub>3</sub>
  • HY-169528S
    Telmisartan-d3 Acyl-Beta-D-glucuronide
    Telmisartan-d3 Acyl-Beta-D-glucuronide is the deuterium labeled WAY-329341 (HY-169528).
    Telmisartan-d<sub>3</sub> Acyl-Beta-D-glucuronide
  • HY-143913S
    Aripiprazole metabolite-d6
    Aripiprazole metabolite-d6 is the deuterium labeled Aripiprazole metabolite.
    Aripiprazole metabolite-d<sub>6</sub>
  • HY-W011117S1
    Danofloxacin-d3-1
    99.85%
    Danofloxacin-d3-1 is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase.
    Danofloxacin-d<sub>3</sub>-1
  • HY-17387S1
    (-)-Huperzine A-d4 hydrochloride
    (-)-Huperzine A-d4 hydrochloride is deuterated labeled (-)-Huperzine A (HY-17387). (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease.
    (-)-Huperzine A-d<sub>4</sub> hydrochloride
  • HY-18986S
    SAR405838-d10
    SAR405838-d10 (MI-77301-d10) is the deuterium labeled SAR405838 (HY-18986). SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a Ki of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity.
    SAR405838-d<sub>10</sub>