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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9621):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W654377
    Triptolide-d3(major) (>90%)
    Triptolide-d3 (major) (>90%) is the deuterium labeled Triptolide (HY-32735). Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.
    Triptolide-d<sub>3</sub>(major) (>90%)
  • HY-W008579S
    1,5-Bis(3,4-dimethoxyphenyl)penta-1,4-dien-3-one-d12
    1,5-Bis(3,4-dimethoxyphenyl)penta-1,4-dien-3-one-d12 is the deuterium labeled 1,5-Bis(3,4-dimethoxyphenyl)penta-1,4-dien-3-one.
    1,5-Bis(3,4-dimethoxyphenyl)penta-1,4-dien-3-one-d<sub>12</sub>
  • HY-143907S
    Atorvastatin EP impurity H-d5
    Atorvastatin EP impurity H-d5 is the deuterium labeled Atorvastatin EP impurity H.
    Atorvastatin EP impurity H-d<sub>5</sub>
  • HY-146845S
    17:0-22:4 PE-d5
    17:0-22:4 PE-d5 is deuterium labeled 17:0-22:4 PE.
    17:0-22:4 PE-d<sub>5</sub>
  • HY-N0059S3
    D-Arabinose-13C-3
    D-Arabinose-13C-3 is the 13C labeled D-Arabinose (HY-N0059). D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinose-<sup>13</sup>C-3
  • HY-100642S1
    3-O-Methyltolcapone-d4
    3-O-Methyltolcapone-d4 is the deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease.
    3-O-Methyltolcapone-d<sub>4</sub>
  • HY-146717S
    N-Acetyl-S-(3-hydroxypropyl)-L-cysteine-d6 dicyclohexylamine
    N-Acetyl-S-(3-hydroxypropyl)-L-cysteine-d6 (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(3-hydroxypropyl)-L-cysteine.
    N-Acetyl-S-(3-hydroxypropyl)-L-cysteine-d<sub>6</sub> dicyclohexylamine
  • HY-W743303
    8-Nitro-1-pyrenol-d8
    8-Nitro-1-pyrenol-d8 is the deuterium labeled 8-Nitro-1-pyrenol.
    8-Nitro-1-pyrenol-d<sub>8</sub>
  • HY-W008625S
    1-Bromohexadecane-16,16,16-d3
    1-Bromohexadecane-16,16,16-d3 is the deuterium labeled 1-Bromohexadecane.
    1-Bromohexadecane-16,16,16-d<sub>3</sub>
  • HY-W010179S
    2-Methoxynaphthalene-d7
    2-Methoxynaphthalene-d7 is the deuterium labeled 2-Methoxynaphthalene.
    2-Methoxynaphthalene-d<sub>7</sub>
  • HY-W739770
    3-Methyl-2-buten-1-ol-d6
    3-Methyl-2-buten-1-ol-d6 is the deuterium labeled 3-Methyl-2-buten-1-ol (HY-W013035). 3-Methyl-2-buten-1-ol (MBO321) is an orally active endogenous metabolite found in pine trees and is used as a fragrance ingredient in cosmetics and detergents. 3-Methyl-2-buten-1-ol passes cell barrier. 3-Methyl-2-buten-1-ol reduces body weight in rats.
    3-Methyl-2-buten-1-ol-d<sub>6</sub>
  • HY-W110702S
    1-Bromotridecane-d27
    1-Bromotridecane-d27 is the deuterium labeled 1-Bromotridecane.
    1-Bromotridecane-d<sub>27</sub>
  • HY-151895S
    (±)-1-Hexadecanoyl-3-chloropropane-dd5-diol
    (±)-1-Hexadecanoyl-3-chloropropane-dd5-diol is the deuterium labeled (±)-1-Hexadecanoyl-3-chloropropane-diol.
    (±)-1-Hexadecanoyl-3-chloropropane-dd<sub>5</sub>-diol
  • HY-10284S3
    Linagliptin-d3-1
    Linagliptin-d3-1 (BI 1356-d3-1) is the deuterium labeled Linagliptin (HY-10284). Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
    Linagliptin-d<sub>3</sub>-1
  • HY-W011817S
    1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone-d3
    1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone-d3 is the deuterium labeled 1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone.
    1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone-d<sub>3</sub>
  • HY-10585S3
    Valproic acid-d4 sodium
    Valproic acid-d4 (sodium) is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.
    Valproic acid-d<sub>4</sub> sodium
  • HY-W744788
    Amitriptylinoxide-d6
    Amitriptylinoxide-d6 (Equilibrin-d6) is the deuterium labeled Amitriptylinoxide (HY-107032). Amitriptylinoxide (Equilibrin) is an analogue and metabolite of amitriptyline with similar antidepressant efficacy.
    Amitriptylinoxide-d<sub>6</sub>
  • HY-157077S
    5-Hydroxysaxagliptin-13C,d2 trifluoroacetate
    5-Hydroxysaxagliptin-13C,d2 (TFA) is 13C-labeled 5-Hydroxysaxagliptin.
    5-Hydroxysaxagliptin-<sup>13</sup>C,d<sub>2</sub> trifluoroacetate
  • HY-W710742
    N,N-Diethylbenzamide-d5
    N,N-Diethylbenzamide-d5 (Benzoyldiethylamine-d5) is the deuterium labeled N,N-Diethylbenzamide (HY-124545).
    N,N-Diethylbenzamide-d<sub>5</sub>
  • HY-34628S
    Tri-O-acetyl-D-glucal-13C
    3,4,6-Tri-O-acetyl-D-glucal-13C is the 13C labeled 3,4,6-Tri-O-acetyl-D-glucal.
    Tri-O-acetyl-D-glucal-<sup>13</sup>C