2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9621):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y1718S
    Tridecanoic acid-d2
    		98.71%
    Tridecanoic acid-d2 is the deuterium labeled Tridecanoic acid. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation.
    Tridecanoic acid-d<sub>2</sub>
  • HY-B0099S
    Edaravone-d5
    		99.52%
    Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
    Edaravone-d<sub>5</sub>
  • HY-W440409
    2,2′-Bipyridine-d8
    		99.33%
    2,2′-Bipyridine-d8 is the deuterium labeled 2,2′-Bipyridine-d8.
    2,2′-Bipyridine-d<sub>8</sub>
  • HY-107542S2
    Oleoylethanolamide-d2
    		≥98.0%
    Oleoylethanolamide-d2 is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.
    Oleoylethanolamide-d<sub>2</sub>
  • HY-D0844S
    Glutathione oxidized-13C4,15N2
    		99.80%
    Glutathione oxidized-13C4,15N2 is the 13C and 15N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes.
    Glutathione oxidized-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-139392S
    Octanoyl-L-carnitine-d3 chloride
    		99.97%
    Octanoyl-L-carnitine-d3 (chloride) is the deuterium labeled Octanoyl-L-carnitine chloride.
    Octanoyl-L-carnitine-d<sub>3</sub> chloride
  • HY-Y0337S6
    L-Cysteine-d2
    		98.67%
    L-Cysteine-d2 is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.
    L-Cysteine-d<sub>2</sub>
  • HY-15209S
    Repaglinide-d5
    		99.87%
    Repaglinide-d5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus.
    Repaglinide-d<sub>5</sub>
  • HY-B0208S
    Methimazole-d3
    		99.72%
    Methimazole-d3 is a deuterium labeled Methimazole (HY-B0208). Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity.
    Methimazole-d<sub>3</sub>
  • HY-12454S
    DM4-d6
    		99.11%
    DM4-d6 is deuterium labeled DM4. DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.
    DM4-d<sub>6</sub>
  • HY-W587724S
    6β-Hydroxy Cortisol-d4
    		99.14%
    6β-Hydroxy Cortisol-d4 is a deuterium labeled compound.
    6β-Hydroxy Cortisol-d<sub>4</sub>
  • HY-N1423S1
    Glycocholic acid-d5
    Glycocholic acid-d5 is the deuterium labeled Glycocholic acid. Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways.
    Glycocholic acid-d<sub>5</sub>
  • HY-B0561S1
    Spironolactone-d3
    		99.82%
    Spironolactone-d3 is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes.
    Spironolactone-d<sub>3</sub>
  • HY-15036S1
    Diclofenac-13C6
    		99.90%
    Diclofenac-13C6 is the 13C6 labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
    Diclofenac-<sup>13</sup>C<sub>6</sub>
  • HY-B0113S3
    Omeprazole-13C,d3
    		98.00%
    Omeprazole-13C,d3 is a 13C-labeled and deuterium labeled Omeprazole. Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria.Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
    Omeprazole-<sup>13</sup>C,d<sub>3</sub>
  • HY-B0561S
    Spironolactone-d7
    		99.96%
    Spironolactone-d7 is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes.
    Spironolactone-d<sub>7</sub>
  • HY-Y0284S
    Diethyl phthalate-d4
    		99.78%
    Diethyl phthalate-d4 is the deuterium labeled Diethyl phthalate.
    Diethyl phthalate-d<sub>4</sub>
  • HY-B1899S
    Taurodeoxycholic acid-d5
    Taurodeoxycholic acid-d5 is the deuterium labeled Taurodeoxycholic acid (HY-B1899). Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid exhibits neuroprotective effect in 3-nitropropionic acid induced mouse model or genetic mouse model of Huntington's disease (HD).
    Taurodeoxycholic acid-d<sub>5</sub>
  • HY-B0210S
    Cefoperazone-d5
    		98.58%
    Cefoperazone-d5 is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity.
    Cefoperazone-d<sub>5</sub>
  • HY-W014423S3
    L-Histidine-13C6,15N3 hydrochloride hydrate
    		99.53%
    L-Histidine-13C6,15N3 (hydrochloride hydrate) is the 13C- and 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>3</sub> hydrochloride hydrate