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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9621):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-117743AS1
    Eprosartan-d6 hydrochloride
    Eprosartan-d6 hydrochloride is deuterated labeled Eprosartan.
    Eprosartan-d<sub>6</sub> hydrochloride
  • HY-B1729S
    Phenoxyethanol-d2
    Phenoxyethanol-d2 is the deuterium labeled Phenoxyethanol. Phenoxyethanol has a broad spectrum of antimicrobial agent. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al.
    Phenoxyethanol-d<sub>2</sub>
  • HY-W700847
    4-(3-Aminobutyl)phenol-d6
    4-(3-Aminobutyl)phenol-d6 (p-Hydroxyhomoamphetamine-d6) is the deuterium labeled 4-(3-Aminobutyl)phenol (HY-W342198).
    4-(3-Aminobutyl)phenol-d<sub>6</sub>
  • HY-B0412S4
    Estriol-d3-1
    Estriol-d3-1 is the deuterium labeled Estriol.
    Estriol-d<sub>3</sub>-1
  • HY-17042AS1
    Cetirizine-d8 dihydrochloride
    Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
    Cetirizine-d<sub>8</sub> dihydrochloride
  • HY-W765177
    Acetyl-L-carnitine hydrochloride-13C3
    Acetyl-L-carnitine hydrochloride-13C3 (O-Acetyl-L-carnitine hydrochloride-13C3) is the 13C-labeled Acetyl-L-carnitine hydrochloride (HY-B0762). Acetyl-L-carnitine (O-Acetyl-L-carnitine; ALCAR) hydrochloride is an orally active mitochondrial energy metabolism regulator and neuroprotectant that can penetrate the blood-brain barrier. Acetyl-L-carnitine hydrochloride selectively enters cells and the brain through the organic cation transporter OCTN2. Acetyl-L-carnitine hydrochloride can participate in fatty acid β-oxidation, promote acetylcholine synthesis, regulate mitochondrial function and inhibit oxidative stress as an acetyl donor. Acetyl-L-carnitine hydrochloride exerts its activity by enhancing energy metabolism, protecting neurons and improving synaptic plasticity. Acetyl-L-carnitine hydrochloride is mainly used in the study of neurodegenerative diseases and metabolic disorder-related diseases such as neonatal hypoxic-ischemic brain damage, Alzheimer's disease, and depression.
    Acetyl-L-carnitine hydrochloride-<sup>13</sup>C<sub>3</sub>
  • HY-U00131S
    Sulfabrom-d4
    Sulfabrom-d4 (N 3517-d4) is is the deuterium labeled Sulfabrom (HY-U00131). Sulfabrom is a long-acting Sulfonamide that is used for the treatment of coccidiosis and various bacterial infections in the poultry, swine and cattle.
    Sulfabrom-d<sub>4</sub>
  • HY-W699428
    Diethyl 2-(methyl-d3)-2-propylmalonate
    Diethyl 2-(methyl-d3)-2-propylmalonate is the deuterium labeled Diethyl 2-methyl-2-propylmalonate (HY-W699429).
    Diethyl 2-(methyl-d<sub>3</sub>)-2-propylmalonate
  • HY-14258AS1
    Escitalopram-d4 oxalate
    Escitalopram-d4 (oxalate) is deuterium labeled Escitalopram (oxalate). Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram oxalate has ~30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression.
    Escitalopram-d<sub>4</sub> oxalate
  • HY-114293S4
    Acetyl coenzyme A-13C2-1 sodium
    Acetyl coenzyme A-13C2-1 sodium (Acetyl-CoA-13C2-1 sodium) is the 13C-labeled Acetyl coenzyme A (HY-114293). Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis.
    Acetyl coenzyme A-<sup>13</sup>C<sub>2</sub>-1 sodium
  • HY-W714767
    Octisalate-d4
    Octisalate-d4 (Octyl salicylate-d4; 2-Ethylhexyl salicylate-d4) is the deuterium labeled Octisalate (HY-B0929). Octisalate (Octyl salicylate) is an organic compound with high lipophilicity, which is used in sunscreens and cosmetics that absorbs UVB rays.
    Octisalate-d<sub>4</sub>
  • HY-W727304
    2,2-Bis(methyl-d3)propane-1,3-diol
    2,2-Bis(methyl-d3)propane-1,3-diol is the deuterium labeled 2,2-Dimethylpropane-1,3-diol (HY-W010584).
    2,2-Bis(methyl-d<sub>3</sub>)propane-1,3-diol
  • HY-W769272
    rac Metoprolol Hemi (+)-Tartrate-d6
    rac Metoprolol Hemi (+)-Tartrate-d6 is the deuterium labeled rac Metoprolol Hemi (+)-Tartrate.
    rac Metoprolol Hemi (+)-Tartrate-d<sub>6</sub>
  • HY-107116S
    MAP4343-d4
    MAP4343-d4 is the deuterium labeled MAP4343. MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents.
    MAP4343-d<sub>4</sub>
  • HY-W758126
    (R)-Brivanib alaninate-d4
    (R)-Brivanib alaninate-d4 is the deuterium-labeled Brivanib (alaninate) (HY-10336). Brivanib alaninate (BMS-582664) is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM; has moderate potency against VEGFR-1 and FGFR-1, but more than 240-fold against PDGFRβ.
    (R)-Brivanib alaninate-d<sub>4</sub>
  • HY-W705718
    Ethyl 3-(ethoxy(methyl-d3)phosphoryl)propanoate
    Ethyl 3-(ethoxy(methyl-d3)phosphoryl)propanoate is the deuterium labeled Ethyl 3-(ethoxy(methyl)phosphoryl)propanoate (HY-W705719).
    Ethyl 3-(ethoxy(methyl-d<sub>3</sub>)phosphoryl)propanoate
  • HY-B0161BS
    (±)-Duloxetine-d7 maleate
    (±)-Duloxetine-d7 (maleate) is deuterium labeled (±)-Duloxetine.
    (±)-Duloxetine-d<sub>7</sub> maleate
  • HY-W016189S
    4,4'-Dihydroxybiphenyl-d8
    4,4'-Dihydroxybiphenyl-d8 is the deuterium labeled 4,4'-Dihydroxybiphenyl.
    4,4'-Dihydroxybiphenyl-d<sub>8</sub>
  • HY-W777546
    (5-Formylfuran-2-yl)methyl acetate-13C6
    (5-Formylfuran-2-yl)methyl acetate-13C6 (Acetic Acid 5-Formylfurfuryl Ester-13C6) is the 13C-labeled (5-Formylfuran-2-yl)methyl acetate (HY-W111899).
    (5-Formylfuran-2-yl)methyl acetate-<sup>13</sup>C<sub>6</sub>
  • HY-113205S
    15-Keto-prostaglandin E2-d9
    15-Keto-prostaglandin E2-d9 is the deuterium labeled 15-Keto-prostaglandin E2.
    15-Keto-prostaglandin E2-d<sub>9</sub>