Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (2)

Isotope-Labeled Compounds Related Products (9621):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-18346S

Mozavaptan-d₆
Mozavaptan-d6 (OPC-31260-d6) is the deuterium labeled Mozavaptan. Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V₂ receptor antagonist with an IC₅₀ of 14 nM. Mozavaptan shows ~85-fold selectivity for V₂ receptor over V₁ receptor (IC₅₀ of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment.

HY-N0538S4

Xylitol-d₇
Xylitol-d₇ is the deuterium labeled Xylit.

HY-W739836

Methscopolamine-d₃ Iodide
Methscopolamine-d₃ Iodide is the deuterium labeled Methscopolamine Iodide.

HY-143803S

Oxaflumazine-d₈ disuccinate
Oxaflumazine-d₈ (disuccinate) is the deuterium labeled Oxaflumazine disuccinate.

HY-W717233

Levomedetomidine-d₄ L-Tartrate
Levomedetomidine-d₄ L-Tartrate is the deuterium labeled Levomedetomidine L-Tartrate.

HY-15388S1

Tazarotene-¹³C₂,d₂
Tazarotene-13C2,d2 (AGN 190168-13C2,d2) is the ¹³C and deuterium labeled isotope of Tazarotene (HY-15388). Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W744625

Olodaterol-d₃ hydrochloride
Olodaterol-d₃ hydrochloride (BI1744-d₃ hydrochloride) is the deuterium labeled Olodaterol hydrochloride (HY-14301A). Olodaterol (BI1744) hydrochloride is a selective, long acting β2-adrenoceptor (β2-AR) agonist (EC₅₀=0.1 nM and pKi= 9.14 for human β2-adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis.

HY-W013396S

4-Iodobenzoic Acid-¹³C₆
4-Iodobenzoic Acid-¹³C₆ is the ¹³C labeled 4-Iodobenzoic Acid.

HY-W767978

1-(4,4-Dimethylthiochroman-6-yl)ethanone-d₈
1-(4,4-Dimethylthiochroman-6-yl)ethanone-d₈ (6-Acetyl-4,4-dimethylthio-chroman-d₈) is the deuterium labeled 1-(4,4-Dimethylthiochroman-6-yl)ethanone (HY-I0187).

HY-14281S

Trilostane-d₃
Trilostane-d₃ is the deuterium-labeled Trilostane (HY-14281). Trilostane-d₃ (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane-d₃ is a synthetic nonhormonal steroid. Trilostane-d₃ can be used for the research of breast cancer and prostate cancer.

HY-146796S

15:0 Cholesteryl ester-d₇
15:0 Cholesteryl ester-d₇ is deuterium labeled 15:0 Cholesteryl ester.

HY-B1322AS1

Amodiaquine-d₁₀ hydrochloride
Amodiaquine-d₁₀ hydrochloride is deuterated labeled Amodiaquine (HY-B1322A). Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC₅₀ of ~20 μM. Anti-inflammatory effect.

HY-151082S

2,2′,3,4,5,5′-Hexachlorobiphenyl-3′,4′,6′-d₃
2,2′,3,4,5,5′-Hexachlorobiphenyl-3′,4′,6′-d₃ is the deuterium labeled 2,2′,3,4,5,5′-Hexachlorobiphenyl.

HY-W743952

Nicergoline-d₃
Nicergoline-d₃ is the deuterium labeled Nicergoline (HY-B0702). Nicergoline, an ergoline derivative ester of bromonicotinic acid, is a potent, selective and orally active antagonist of α1A-adrenoceptor. Nicergoline has vasodilator effects. Nicergoline also has ameliorative effects on cognitive function in mouse models of Alzheimer's disease.

HY-W742622

N-Benzyloxy Naratriptan-d₃
N-Benzyloxy Naratriptan-d₃ is the deuterium labeled N-Benzyloxy Naratriptan.

HY-W751140

(2-Aminothiazole-4-yl)acetic acid-¹³C,¹⁵N₂
(2-Aminothiazole-4-yl)acetic acid-¹³C,¹⁵N₂ (2-Amino-4-thiazoleacetic Acid-¹³C,¹⁵N₂) is the ¹³C- and ¹⁵N-labeled (2-Aminothiazole-4-yl)acetic acid (HY-I1212).

HY-146600S

Hydroxyfenbendazole-d₃
Hydroxyfenbendazole-d₃ is the deuterium labeled Hydroxyfenbendazole.

HY-13720S

Pergolide-d₇ hydrochloride
Pergolide-d₇ hydrochloride is deuterated labeled Pergolide (HY-13720). Pergolide (LY127809 (free base)) is an ergot-derived orally active dopamine receptor agonist. Pergolide can be used for Parkinson disease research.

HY-122765S

Luxabendazole-d₃
Luxabendazole-d₃ is the deuterium labeled Luxabendazole.

HY-Y1300S

Ethylene carbonate-d₄
Ethylene carbonate-d₄ is the deuterium labeled Ethylene carbonate.

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