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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9620):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-143666S
    DPPI-3,4,5-P3-d62 sodium
    DPPI-3,4,5-P3-d62 (sodium) is the deuterium labeled DPPI-3,4,5-P3 sodium.
    DPPI-3,4,5-P3-d<sub>62</sub> sodium
  • HY-13570S1
    Betamethasone-d5-1
    Betamethasone-d5-1 is deuterium labeled Betamethasone. Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis.
    Betamethasone-d<sub>5</sub>-1
  • HY-W702077
    3-Chloro-2-methyl-1,1'-biphenyl-d5
    3-Chloro-2-methyl-1,1'-biphenyl-d5 (3-Chloro-2-methylbiphenyl-d5) is the deuterium labeled 3-Chloro-2-methyl-1,1'-biphenyl (HY-W094186).
    3-Chloro-2-methyl-1,1'-biphenyl-d<sub>5</sub>
  • HY-B0553S
    Methazolamide-d6
    Methazolamide-d6 is the deuterium labeled Methazolamide. Methazolamide (L584601) is a sulfonamide derivative used as a carbonic anhydrase inhibitor with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide, an intraocular pressure-lowering agent, reduces intraocular pressure elevations associated with glaucoma and other ocular disorders.
    Methazolamide-d<sub>6</sub>
  • HY-B0546AS
    Procaine-d4 hydrochloride
    Procaine-d4 (hydrochloride) is the deuterium labeled Procaine hydrochloride. Procaine hydrochloride is a DNA-demethylating agent. Procaine hydrochloride acts through multiple targets and has a slow onset and a short duration of action.
    Procaine-d<sub>4</sub> hydrochloride
  • HY-N7092AS
    L-Fructose-1-13C
    L-Fructose-1-13C is the 13C labeled L-Fructose.
    L-Fructose-1-<sup>13</sup>C
  • HY-W750538
    Flumazenil Carboxylic Acid-d3
    Flumazenil Carboxylic Acid-d3 is the deuterium labeled Flumazenil Carboxylic Acid.
    Flumazenil Carboxylic Acid-d<sub>3</sub>
  • HY-W751834
    6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione-13C3
    6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione-13C3 (NSC 99321-13C3) is the 13C-labeled 6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione (HY-W016913).
    6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione-<sup>13</sup>C<sub>3</sub>
  • HY-136380S
    Clodinafop-propargyl-13C6
    Clodinafop-propargyl-13C6 is the 13C-labeled Clodinafop-propargyl. Clodinafop-propargyl, a main member of aryloxyphenoxy-propionate herbicides, is used for postemergence control of annual grasses in cereals, including Avena, Lolium, Setaria, Phalaris and Alopecurus spp. Clodinafop-propargyl-13C6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Clodinafop-propargyl-<sup>13</sup>C<sub>6</sub>
  • HY-D0839S1
    Tetradecyltrimethylammonium-d29 bromide
    Tetradecyltrimethylammonium-d29 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide). Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure.
    Tetradecyltrimethylammonium-d<sub>29</sub> bromide
  • HY-W768514
    (3b,22E)-Ergosta-5,7,22-triene-3,24,25-triol-d3
    (3b,22E)-Ergosta-5,7,22-triene-3,24,25-triol-d3 is the deuterium labeled (3b,22E)-Ergosta-5,7,22-triene-3,24,25-triol.
    (3b,22E)-Ergosta-5,7,22-triene-3,24,25-triol-d<sub>3</sub>
  • HY-W009412S
    D-Phenyl-alanine-N-t-Boc-d5
    99.85%
    D-Phenyl-alanine-N-t-Boc-d5 is the deuterium labeled D-Phenyl-alanine-N-t-Boc.
    D-Phenyl-alanine-N-t-Boc-d<sub>5</sub>
  • HY-N0059S6
    D-Arabinose-d6
    D-Arabinose-d6 is the deuterium labeled D-Arabinose (HY-N0059). D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinose-d<sub>6</sub>
  • HY-B0574S2
    Mefenamic acid-13C6
    Mefenamic acid-13C6 is the 13C-labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively.
    Mefenamic acid-<sup>13</sup>C<sub>6</sub>
  • HY-W777757
    4,5-Diamino-6-hydroxypyrimidine-13C,15N
    4,5-Diamino-6-hydroxypyrimidine-13C,15N (5,6-Diamino-4-pyrimidinol-13C,15N) is the 13C- and 15N-labeled 4,5-Diamino-6-hydroxypyrimidine (HY-32223).
    4,5-Diamino-6-hydroxypyrimidine-<sup>13</sup>C,<sup>15</sup>N
  • HY-79128S2
    Fmoc-L-Lys (Boc)-OH-13C
    Fmoc-L-Lys (Boc)-OH-13C (Fmoc-L-Lys(Boc)-OH-13C) is 13C labeled Fmoc-L-Lys (Boc)-OH. Fmoc-L-Lys (Boc)-OH is a lysine derivative.
    Fmoc-L-Lys (Boc)-OH-<sup>13</sup>C
  • HY-138616S3
    dGTP-13C10 dilithium
    98.8%
    dGTP-13C10 (2'-Deoxyguanosine-5'-triphosphate-13C10) dilithium is 13C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
    dGTP-<sup>13</sup>C<sub>10</sub> dilithium
  • HY-90009AS
    Tadalafil-13C2,d3
    Tadalafil-13C2,d3 is 13C and deuterated labeled Tadalafil (HY-90009A). Tadalafil (IC-351) is a PDE5 inhibitor with an IC50 value of 1.8 nM.
    Tadalafil-<sup>13</sup>C<sub>2</sub>,d<sub>3</sub>
  • HY-N0464S
    Quinic acid-13C3
    Quinic acid-13C3 is the 13C-labeled D-(-)-Quinic acid. D-(-)-Quinic acid scavenges hydrogen peroxide (IC50=87.11 μg/mL) and exhibits antioxidant activity. D-(-)-Quinic acid is the inhibitor for MAO and α-Glucosidase (IC50 =93.75 μg/mL). D-(-)-Quinic acid is orally active.
    Quinic acid-<sup>13</sup>C<sub>3</sub>
  • HY-W710036
    Erythromycin A 9-oxime-d3
    Erythromycin A 9-oxime-d3 is the deuterium labeled Erythromycin oxime (HY-134518). Erythromycin oxime is an intermediate of Azithromycin (HY-17506). Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
    Erythromycin A 9-oxime-d<sub>3</sub>