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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9669):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W013940S1
    DL-Cystine-d6
    99.81%
    DL-Cystine-d6 is the deuterium labeled DL-Cystine (HY-W013940). DL-Cystine is a cysteine derivative.
    DL-Cystine-d<sub>6</sub>
  • HY-W017522S1
    Adipic acid-13C6
    ≥98.0%
    Adipic acid-13C6 (Hexanedioic acid-13C6) is the 13C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc.
    Adipic acid-<sup>13</sup>C<sub>6</sub>
  • HY-B0356AS1
    Ciprofloxacin-13C3,15N monohydrochloride
    99.9%
    Ciprofloxacin-13C3,15N (Bay-09867-13C3,15N) monohydrochloride is 13C- and 15N-labeled Ciprofloxacin (monohydrochloride) (HY-B0356A).
    Ciprofloxacin-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N monohydrochloride
  • HY-33212S
    D-N-Acetylgalactosamine-13C
    99.95%
    D-N-Acetylgalactosamine-13C is the 13C labeled D-N-Acetylgalactosamine. D-N-Acetylgalactosamine is an endogenous metabolite.
    D-N-Acetylgalactosamine-<sup>13</sup>C
  • HY-150627S
    Pyrene-d10
    99.88%
    Pyrene-d10 is the deuterium labeled Pyrene.
    Pyrene-d<sub>10</sub>
  • HY-N2027S
    Taurochenodeoxycholic acid-d4 sodium
    99.20%
    Taurochenodeoxycholic acid-d4 (sodium) is the deuterium labeled Taurochenodeoxycholic acid. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties.
    Taurochenodeoxycholic acid-d<sub>4</sub> sodium
  • HY-132425S
    6-Hydroxy Melatonin-d4
    6-Hydroxy Melatonin-d4 is the deuterium labeled 6-Hydroxy Melatonin.
    6-Hydroxy Melatonin-d<sub>4</sub>
  • HY-13740S
    Resiquimod-d5
    99.84%
    Resiquimod-d5 is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.
    Resiquimod-d<sub>5</sub>
  • HY-17589AS
    Chloroquine-d5
    99.90%
    Chloroquine-d5 is deuterium labeled Chloroquine (HY-17589A). Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
    Chloroquine-d<sub>5</sub>
  • HY-W012926S1
    Dihydrouracil-d4
    99.97%
    Dihydrouracil-d4 is the deuterium labeled Dihydrouracil. Dihydrouracil (HY-W012926), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient.
    Dihydrouracil-d<sub>4</sub>
  • HY-17580S
    Fidaxomicin-d7
    Fidaxomicin-d7 (OPT-80-D7) is the deuterium labeled Fidaxomicin. Fidaxomicin (OPT-80), a macrocyclic RNA polymerase inhibitor, has a narrow spectrum of activity. Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora.
    Fidaxomicin-d<sub>7</sub>
  • HY-17618S
    Pemafibrate-d4
    99.80%
    Pemafibrate-d4 is deuterated labeled Pemafibrate (HY-17618). Pemafibrate is a highly selective PPARα agonist, with an EC50 of 1 nM.
    Pemafibrate-d<sub>4</sub>
  • HY-10585AS1
    Valproic acid-d14 sodium
    Valproic acid-d14 (sodium) is deuterium labeled Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.
    Valproic acid-d<sub>14</sub> sodium
  • HY-B0234S1
    Estrone-d2
    99.78%
    Estrone-d2 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells.
    Estrone-d<sub>2</sub>
  • HY-12033S2
    2-Methoxyestradiol-d5
    98.67%
    2-Methoxyestradiol-d5 is the deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa.
    2-Methoxyestradiol-d<sub>5</sub>
  • HY-17620S
    Sacubitrilat-d4
    99.28%
    Sacubitrilat-d4 is the deuterium labeled Sacubitrilat. Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor.
    Sacubitrilat-d<sub>4</sub>
  • HY-132404S
    (rac)-3-O-Methyl DOPA-d3
    98.73%
    (rac)-3-O-Methyl DOPA-d3 is the deuterium labeled (rac)-3-O-Methyl DOPA.
    (rac)-3-O-Methyl DOPA-d<sub>3</sub>
  • HY-B0204S1
    Pimobendan-d3
    99.43%
    Pimobendan-d3 (UD-CG115-d3) is deuterium labeled Pimobendan (HY-B0204). Pimobendan (UD-CG115) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
    Pimobendan-d<sub>3</sub>
  • HY-N0113S
    Hordenine-d6
    98.03%
    Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production.
    Hordenine-d<sub>6</sub>
  • HY-B1363S
    Bendroflumethiazide-d5
    98.58%
    Bendroflumethiazide-d5 (Bendrofluazide-d5) is the deuterium labeled Bendroflumethiazide (HY-B1363).Bendroflumethiazide (Bendrofluazide) is an orally available diuretic. Bendroflumethiazide inhibits the electroneutral sodium-chloride symporter located in the apical membrane of the early segment of the distal convoluted tubule and can effectively lower blood pressure. Bendroflumethiazide is used in the study of hypertension and edema. Bendroflumethiazide has an antidiuretic effect in diabetes insipidus.
    Bendroflumethiazide-d<sub>5</sub>