Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitor (1)

Isotope-Labeled Compounds Related Products (7658):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-133668S

Monoethyl phthalate-d₄		98.27%
Monoethyl phthalate-d₄ is the deuterium labeled Monoethyl phthalate[1]. Monoethyl phthalate is a metabolite of diethyl phthalate. Monoethyl phthalate acts as a urinary biomarker of phthalates exposure indicating the risks of thyroid cancer and benign nodule[2][3].

HY-D0227ES

THAM-d₁₁ (for molecular biology)		99.96%
Trometamol(Tris),for molecular biology-d₁₁ is the deuterium labeled Trometamol(Tris),for molecular biology[1].

HY-B0405S

Bupivacaine-d₉		99.04%
Bupivacaine-d₉9 is a deuterium labeled Bupivacaine. Bupivacaine is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain[1][2][3].

HY-131113S

N-Nitrosodibutylamine-d₁₈		99.53%
N-Nitrosodibutylamine-d₁₈ is the deuterium labeled N-Nitrosodibutylamine[1]. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water[2].

HY-109590S2

Arachidonic acid-d₁₁		98.00%
Arachidonic acid-d₁₁ is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes[1][2].

HY-21323S

Isophthalic-2,4,5,6 Acid-d₄		99.73%
Isophthalic-2,4,5,6 Acid-d₄ is the deuterium labeled Isophthalic acid[1].

HY-B1374S1

Florfenicol-d₃		99.90%
Florfenicol-d₃ is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.

HY-113416AS

Dehydroepiandrosterone sulfate-d₆ sodium dihydrate		98.00%
Dehydroepiandrosterone sulfate sodium dihydrate-d₆ sodium dihydrate is the deuterium labeled Dehydroepiandrosterone sulfate sodium dihydrate. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium dihydrate is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium dihydrate has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate sodium dihydrate can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium dihydrate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium dihydrate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality.

HY-B1716S2

L-5-Hydroxytryptophan-d₄		98.71%
L-5-Hydroxytryptophan-d₄ (L-5-HTP-d₄; Oxitriptan-d₄) is a deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia.

HY-W018772S12

D-Ribose-d₆		99.86%
D-Ribose-d₆ is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein gl

HY-W020005

2-Carboxyphenol-d₄		99.14%
2-Carboxyphenol-d4 is the deuterium labeled 2-Carboxyphenol. 2-Carboxyphenol is a plant hormone and mediates host responses against microbial pathogens.

HY-158084S

N-Nonanoylglycine-d₂
N-Nonanoylglycine-d₂ is the deuterated labeled N-Nonanoylglycine.

HY-B0282AS

Acetylcholine-d₉ bromide		98.86%
Acetylcholine-d₉ (bromide) is the deuterium labeled Acetylcholine bromide.

HY-143996S

Mevalonic acid-¹³C,d₃ sodium		≥99.0%
Mevalonic acid-¹³C,d₃ (sodium) is the ¹³C- and deuterium labeled Mevalonic acid[1].

HY-Y1033S

Methyl-triphenylphosphonium-d₃ bromide		≥99.0%
Methyl-triphenylphosphonium-d₃ (bromide) is the deuterium labeled Methyl-triphenylphosphonium bromide[1].

HY-114277S

Sotorasib-d₇		98.88%
Sotorasib-d₇ (AMG-510-d₇) is a deuterium-labeled Sotorasib (HY-114277). Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C‑mutated locally advanced or metastatic non‑small cell lung cancer (NSCLC).

HY-139417S

Docosapentaenoic acid-d₅		99.30%
Docosapentaenoic acid-d₅ is the deuterium labeled Docosapentaenoic acid[1].

HY-B0537AS

Pentamidine-d₄ dihydrochloride		≥98.0%
Pentamidine-d₄ (dihydrochloride) is the deuterium labeled Pentamidine dihydrochloride. Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities[1][2][3][4].

HY-N0215S2

L-Phenylalanine-¹³C		99.66%
L-Phenylalanine-¹³C is the ¹³C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

HY-15027S1

5-Aminosalicylic acid-d₃		99.38%
5-Aminosalicylic acid-d₃ is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1][2][3][4].

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