2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9709):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W012889S
    DL-Valine-d8
    		≥99.0%
    DL-Valine-d8 is the deuterium labeled DL-Valine.
    DL-Valine-d<sub>8</sub>
  • HY-50936S
    Trabectedin-d3
    		99.08%
    Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment.
    Trabectedin-d<sub>3</sub>
  • HY-14649S4
    Retinoic acid-d5
    		98.25%
    Retinoic acid-d5 is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
    Retinoic acid-d<sub>5</sub>
  • HY-N0322S2
    Cholesterol-d6-1
    		99.01%
    Cholesterol-d6-1 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol-d<sub>6</sub>-1
  • HY-19696AS
    Tauroursodeoxycholate-d4 sodium
    		99.50%
    Tauroursodeoxycholate-d4 (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.
    Tauroursodeoxycholate-d<sub>4</sub> sodium
  • HY-13757AS
    Tamoxifen-d5
    		99.99%
    Tamoxifen-d5 is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM). Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity.
    Tamoxifen-d<sub>5</sub>
  • HY-32735S
    Triptolide-d3
    Triptolide-d3 is the deuterium labeled Triptolide. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.
    Triptolide-d<sub>3</sub>
  • HY-B1732S3
    DL-3-Phenylalanine-13C-1
    DL-3-Phenylalanine-13C-1 is the 13C labeled DL-3-Phenylalanine.
    DL-3-Phenylalanine-<sup>13</sup>C-1
  • HY-N0682S3
    Pyridoxine-13C4 hydrochloride
    		98.00%
    Pyridoxine-13C4 (hydrochloride) is the 13C-labeled Pyridoxine (hydrochloride). Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine-<sup>13</sup>C<sub>4</sub> hydrochloride
  • HY-B0125S
    Ofloxacin-d3
    		99.77%
    Ofloxacin-d3 is the deuterium labeled Ofloxacin.
    Ofloxacin-d<sub>3</sub>
  • HY-N1446S3
    Oleic acid-d17
    		≥98.0%
    Oleic acid-d17 is the deuterium labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.
    Oleic acid-d<sub>17</sub>
  • HY-15598S
    20-HETE-d6
    		≥99.0%
    20-HETE-d6 is the deuterium labeled 20-HETE.
    20-HETE-d<sub>6</sub>
  • HY-N0305S1
    5-Aminolevulinic acid-d2 hydrochloride
    5-Aminolevulinic acid-d2 (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).
    5-Aminolevulinic acid-d<sub>2</sub> hydrochloride
  • HY-W019838S
    D-Erythro-dihydrosphingosine-d7
    		99.00%
    D-Erythro-dihydrosphingosine-d7 is the deuterium labeled D-Erythro-dihydrosphingosine. D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.
    D-Erythro-dihydrosphingosine-d<sub>7</sub>
  • HY-B1743S
    Puromycin-d3
    		98.96%
    Puromycin-d3 is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.
    Puromycin-d<sub>3</sub>
  • HY-111772S1
    Elexacaftor-d3
    		99.23%
    Elexacaftor-d3 (VX-445-d3) is the deuterium labeled Elexacaftor (HY-111772).
    Elexacaftor-d3
  • HY-113341S
    7ß-Hydroxycholesterol-d7
    7ß-Hydroxycholesterol-d7 is the deuterium labeled 7α-Hydroxycholesterol. 7β-Hydroxycholesterol is an oxysterol that derived by the oxidation of cholesterol. 7β-hydroxycholesterol can induce cellular oxidative stress, apoptosis, and necrosis, resulting in cytotoxicity. 7β-hydroxycholesterol has antitumor activity.
    7ß-Hydroxycholesterol-d<sub>7</sub>
  • HY-109506S
    DPPC-d62
    		≥99.0%
    DPPC-d62 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice.
    DPPC-d<sub>62</sub>
  • HY-Y0261AS1
    Ammonium sulphate,≥99.0%,AR-15N2
    		99.30%
    Ammonium sulphate,≥99.0%,AR-15N2 is the deuterium labeled Ammonium sulphate,≥99.0%,AR. Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology.
    Ammonium sulphate,≥99.0%,AR-<sup>15</sup>N<sub>2</sub>
  • HY-146879S
    26:0 Lyso PC-d4
    26:0 Lyso PC-d4 is deuterium labeled 26:0 Lyso PC.
    26:0 Lyso PC-d<sub>4</sub>