Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitor (1)

Isotope-Labeled Compounds Related Products (7657):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-N2334S

Glycochenodeoxycholic acid-d₄		98.00%
Glycochenodeoxycholic acid-d₄ is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2].

HY-N0067S3

γ-Aminobutyric acid-¹³C₄		≥99.0%
γ-Aminobutyric acid-¹³C₄ is the ¹³C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

HY-N0322S2

Cholesterol-d₆-1		99.01%
Cholesterol-d₆-1 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.

HY-W014375S2

Arginine-¹³C₆ hydrochloride		99.00%
Arginine-¹³C₆ hydrochloride is ¹³C-labeled Arginine (hydrochloride) (HY-W014375). Arginine hydrochloride is an arginine derivative.

HY-125731S

Glycodeoxycholic acid-d₄		99.52%
Glycodeoxycholic acid-d₄ is the deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is an endogenous metabolite.

HY-N7113S

Squalane-d₆₂
Squalane-d₆₂ is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2].

HY-B1732S3

DL-3-Phenylalanine-¹³C-1
DL-3-Phenylalanine-¹³C-1 is the ¹³C labeled DL-3-Phenylalanine[1].

HY-13694S

Methionine-d₃		99.22%
Methionine-d₃ is the deuterium labeled Methionine. Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation.

HY-N1446S3

Oleic acid-d₁₇		≥98.0%
Oleic acid-d₁₇ is the deuterium labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.

HY-15598S

20-HETE-d₆		≥99.0%
20-HETE-d₆ is the deuterium labeled 20-HETE[1].

HY-15833S

Chlorthalidone-d₄		98.49%
Chlorthalidone-d₄ is the deuterium labeled Chlorthalidone. Chlorthalidone is a thiazide-like diuretic used to treat hypertension.

HY-N0305S1

5-Aminolevulinic acid-d₂ hydrochloride
5-Aminolevulinic acid-d₂ (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).

HY-W017007S

3-Methyl-L-histidine-d₃
3-Methyl-L-histidine-d₃ is the deuterium labeled 3-Methyl-L-histidine. 3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin.

HY-111772S1

Elexacaftor-d3		99.23%
Elexacaftor-d3 (VX-445-d3) is the deuterium labeled Elexacaftor (HY-111772).

HY-113134S

25-Hydroxycholesterol-d₆		≥99.0%
25-Hydroxycholesterol-d₆ (25-OHC-d₆) is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells[1][2].

HY-113341S

7ß-Hydroxycholesterol-d₇
7ß-Hydroxycholesterol-d₇ is the deuterium labeled 7α-Hydroxycholesterol. 7β-Hydroxycholesterol is an oxysterol that derived by the oxidation of cholesterol. 7β-hydroxycholesterol can induce cellular oxidative stress, apoptosis, and necrosis, resulting in cytotoxicity. 7β-hydroxycholesterol has antitumor activity.

HY-146879S

26:0 Lyso PC-d₄
26:0 Lyso PC-d₄ is deuterium labeled 26:0 Lyso PC.

HY-W012499S

N-Acetyl-L-methionine-d₃		99.87%
N-Acetyl-L-methionine-d₃ is the deuterium labeled N-Acetyl-L-methionine. N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine. L-methionine is an indispensable amino acid required for normal growth and development[1].

HY-W012509S

2,5-Dichlorobenzoic acid-d₃
2,5-Dichlorobenzoic acid-d₃ is the deuterium labeled 2,5-Dichlorobenzoic acid. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.

HY-113031S

16α-Hydroxydehydroepiandrosterone-d₆
16α-Hydroxydehydroepiandrosterone-d₆ (16α-Hydroxy-DHEA-d₆) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone[1].

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