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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9716):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100355S1
    C18-Ceramide-d7
    ≥99.0%
    C18-Ceramide-d7 is deuterium labeled C18-Ceramide.
    C18-Ceramide-d<sub>7</sub>
  • HY-40135S
    L-Hydroxyproline-d3
    98.67%
    L-Hydroxyproline-d3 is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
    L-Hydroxyproline-d<sub>3</sub>
  • HY-B0803S1
    Lumefantrine-d9
    Lumefantrine-d9 is the deuterium labeled Lumefantrine. Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs.
    Lumefantrine-d<sub>9</sub>
  • HY-103252S
    Monomethyl fumarate-d3
    98.57%
    Monomethyl fumarate-d3 is a deuterium labeled Monomethyl fumarate (HY-103252). Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF) (HY-17363), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease.
    Monomethyl fumarate-d<sub>3</sub>
  • HY-N0067S3
    γ-Aminobutyric acid-13C4
    ≥99.0%
    γ-Aminobutyric acid-13C4 is the 13C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors).
    γ-Aminobutyric acid-<sup>13</sup>C<sub>4</sub>
  • HY-13694S
    Methionine-d3
    99.22%
    Methionine-d3 is the deuterium labeled Methionine. Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation.
    Methionine-d<sub>3</sub>
  • HY-113472S
    N-Methyl-4-pyridone-3-carboxamide-d3
    99.63%
    N-Methyl-4-pyridone-3-carboxamide-d3 is deuterium labeled N-Methyl-4-pyridone-3-carboxamide.
    N-Methyl-4-pyridone-3-carboxamide-d<sub>3</sub>
  • HY-W355129S
    MeIQx-d3
    ≥99.0%
    MeIQx-d3 is the deuterium labeled MeIQx (HY-W355129). MeIQx is a heterocyclic amine (HAs) compound and a dietary aromatic amine, which can bind covalently to hemoglobin. MeIQx is a mutagenic compound that induces liver tumors.
    MeIQx-d<sub>3</sub>
  • HY-15833S
    Chlorthalidone-d4
    98.49%
    Chlorthalidone-d4 is the deuterium labeled Chlorthalidone. Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
    Chlorthalidone-d<sub>4</sub>
  • HY-N0005S
    Curcumin-d6
    99.78%
    Curcumin-d6 (Diferuloylmethane-d6 ) is deuterium labeled Curcumin (HY-N0005). Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
    Curcumin-d<sub>6</sub>
  • HY-B0451AS7
    Dopamine-d5 hydrochloride
    99.6%
    Dopamine-d5 (hydrochloride) is the deuterium labeled Dopamine (hydrochloride). Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis.
    Dopamine-d<sub>5</sub> hydrochloride
  • HY-18260S1
    Bisphenol A-d6
    99.04%
    Bisphenol A-d6 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders.
    Bisphenol A-d<sub>6</sub>
  • HY-Y0262S1
    Oxalic acid-13C2
    99.45%
    Oxalic acid-13C2 is the deuterium labeled Oxalic acid, 99% (HY-Y0262). Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent.
    Oxalic acid-<sup>13</sup>C<sub>2</sub>
  • HY-W050145S
    Levoglucosan-d7
    ≥99.0%
    Levoglucosan-d7 is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature.
    Levoglucosan-d<sub>7</sub>
  • HY-B1511S
    Cyclic AMP-13C5
    Cyclic AMP-13C5 is a deuterated cyclic AMP.
    Cyclic AMP-<sup>13</sup>C<sub>5</sub>
  • HY-W004260S1
    Arachidic acid-d39
    98.36%
    Arachidic acid-d39 is the deuterium labeled Arachidic acid. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue.
    Arachidic acid-d<sub>39</sub>
  • HY-W013636S2
    2-Ketoglutaric acid-d6
    98.62%
    2-Ketoglutaric acid-d6 (Alpha-Ketoglutaric acid-d6) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM).
    2-Ketoglutaric acid-d<sub>6</sub>
  • HY-N0097S4
    Guanosine-13C10
    99.8%
    Guanosine-13C10 is the 13C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.
    Guanosine-<sup>13</sup>C<sub>10</sub>
  • HY-109037S3
    Mavacamten-d5
    98.61%
    Mavacamten-d5 (MYK461-d5; SAR439152-d5) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
    Mavacamten-d<sub>5</sub>
  • HY-W012954S
    Tetramethylammonium-d12 chloride
    99.94%
    Tetramethylammonium-d12 (chloride) is the deuterium labeled Tetramethylammonium chloride.
    Tetramethylammonium-d<sub>12</sub> chloride