2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D1222
    Vat violet 13
    Vat violet 13 is a violet dye.
    Vat violet 13
  • HY-140948
    (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
    (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
  • HY-D1344
    BDP 630/650 azide
    BDP 630/650 azide is a bright and photostable dye azide (BDP 630/650: Ex=630 nm, Em=650 nm). BDP 630/650 azide can be used for labeling using Click chemistry.
    BDP 630/650 azide
  • HY-N8502
    Urdamycin A
    Urdamycin A (Compound 3b) is an angucycline antibiotic that can be isolated from Streptomyces fradiae. Urdamycin A is an orange indicator with a change of the color to ultramarine blue at pH 7.7. Urdamycin A has anticancer activity with IC50s of 2.4 and 0.55 μg/mL in proliferation and stem cell assays, respectively.
    Urdamycin A
  • HY-D2881C
    RB-PEG-COOH (MW 2000)
    RB-PEG-COOH (MW 2000) (Rhodamine B-PEG-COOH (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 2000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm).
    RB-PEG-COOH (MW 2000)
  • HY-D2190
    Ag2S Oil phase (1200 nm)
    Ag2S Oil phase (1200 nm) is a fluorescent dyes.
    Ag2S Oil phase (1200 nm)
  • HY-D1124
    Mordant brown 1
    Mordant brown 1, a naphthalenesulphonic acid derivative, is an azo dye. Mordant brown 1 is also an effective and specific inhibitor of CD40-CD154 costimulatory protein-protein interaction.
    Mordant brown 1
  • HY-161502
    DHX-SP
    DHX-SP is a fluorescent probe, which visualizes superoxide anion (O2·–) and peroxynitrite (ONOO–) during ferroptosis of PC12 cells and in the Parkinson’s disease model.
    DHX-SP
  • HY-D2886H
    RB-PEG-N3 (MW 10000)
    RB-PEG-N3 (MW 10000) (Rhodamine B-PEG-N3 (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and azide group (N3). RB-PEG-N3 (MW 10000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 546/610 nm).
    RB-PEG-N3 (MW 10000)
  • HY-D2794C
    FITC-PEG-NH2 (MW 10000)
    FITC-PEG-NH2 (MW 10000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG-NH2 (MW 10000) can be used for fluorescent labeling and imaging.
    FITC-PEG-NH2 (MW 10000)
  • HY-D0344
    Giuba Black D
    Direct Grey D exhibits frameshift mutagenic activity.
    Giuba Black D
  • HY-D2335
    SERTlight
    SERTlight is a fluorescent agent that can specifically label serotonergic neuronal cell bodies, dendrites, and axonal projections as fluorescent substrates of the serotonin transporter (SERT). SERTlight is orthogonal to various genetically encoded sensors in terms of optics, pharmacology, and operation, enabling multiple imaging. SERTlight allows the use of GRAB5HT sensors to label distal 5HT axonal projections and simultaneously image the release of endogenous 5HT, providing a new multifunctional molecular tool for studying serotonergic systems.
    SERTlight
  • HY-D2197
    AgAuSe-COOH (1120 nm)
    AgAuSe-COOH (1120 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window.
    AgAuSe-COOH (1120 nm)
  • HY-D1741
    DiOC16(3)
    DiOC16(3) (3,3'-Dihexadecyloxacarbocyanine) is a lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and studies of membrane fluidity.
    DiOC16(3)
  • HY-D2840H
    FITC-mPEG (MW 10000)
    FITC-mPEG (MW 10000) is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG (MW 10000) can be used for fluorescent labeling and imaging.
    FITC-mPEG (MW 10000)
  • HY-NP067
    Galanthus Nivalis Lectin
    Galanthus Nivalis Lectin (GNL) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Galanthus Nivalis Lectin (GNL) is a biological material or organic compound that can be used in life science research.
    Galanthus Nivalis Lectin
  • HY-D1405
    Br-5MP-Fluorescein
    Br-5MP-Fluorescein is a dye reagent for labeling of peptides and proteins.
    Br-5MP-Fluorescein
  • HY-131025
    Janelia Fluor® 585, SE
    Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 585, SE
  • HY-173241
    Poly-L-lysine-Ahx-FITC (MW 15000-30000)
    Poly-L-lysine-Ahx-FITC (MW 15000-30000) is a cationic polymer, which is a polylysine modified with FITC (HY-66019). Poly-L-lysine-Ahx-FITC (MW 15000-30000) is used to fix cells on glass substrates or negatively charged substrates for subsequent labeling and localization experiments.
    Poly-L-lysine-Ahx-FITC (MW 15000-30000)
  • HY-149596
    PTZ-LD
    PTZ-LD is a phenothiazine (HY-Y0055)-based fluorescent probe for lipid droplets (LDs) detection. PTZ-LD is apparently emissive in LDs with high specificity. (Ex/Em=488/570-620 nm). PTZ-LD can be used for diabetic cataract (DC) research.
    PTZ-LD
Cat. No. Product Name / Synonyms Application Reactivity