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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-164055
    HL1
    		99.86%
    HL1 is a ligand for tridentate Schiff bases and is a potential fluorescent probe for metal ions. HL1 exhibits photoluminescence at a weak and strong excitation wavelength of 415 nm.
    HL1
  • HY-D2348
    ACE
    ACE is a non-GFP-like fluorescent dye. ACE can bind to fluorogenic RNA aptamer for the research of visualizing RNAs in live cells.
    ACE
  • HY-15935
    X-Gluc Dicyclohexylamine
    		99.48%
    X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system).
    X-Gluc Dicyclohexylamine
  • HY-D2396
    Sulfo SMCC R-phycoerythrin
    Sulfo SMCC R-phycoerythrin is a conjugate composed of the protein crosslinker SMCC (HY-42360) and R-PE (R-Phycoerythrin) (HY-D0988) that can be used to label proteins to make them carry red fluorescence. Among them, SMCC is able to engage antigen-coupled spleen cells to induce antigen-specific immune responses.
    Sulfo SMCC R-phycoerythrin
  • HY-P4428A
    Z-Val-Lys-Met-AMC TFA
    		Substrate 99.85%
    Z-Val-Lys-Met-AMC TFA is a fluorescent substrate that can be used to detect the β-secretase activity of cathepsin B.
    Z-Val-Lys-Met-AMC TFA
  • HY-D2433
    Glucose-PEG2000-Cy3
    Glucose-PEG2000-Cy3 is a Cy3 (HY-D0822) labeled Glucose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Glucose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery.
    Glucose-PEG2000-Cy3
  • HY-W440914C
    DSPE-PEG-FITC (MW 600)
    DSPE-PEG-FITC (MW 600) is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG-FITC (MW 600) can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers (Ex/Em = 488/525 nm).
    DSPE-PEG-FITC (MW 600)
  • HY-P5057A
    5-FAM-LL-37 TFA
    5-FAM-LL-37 TFA is the TFA salt form of 5-FAM-LL-37 (HY-P5057). 5-FAM-LL-37 TFA is a LL-37 peptide labeled with fluorescein, which retains the antibacterial and immunomodulatory activities of LL-37. 5-FAM-LL-37 TFA binds to the bacterial cell membrane, destroys the integrity of the membrane, and exhibits board-spectrum antibacterial efficacy.
    5-FAM-LL-37 TFA
  • HY-D0531
    C.I. Pigment red 123
    		98.01%
    C.I. Pigment red 123 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
    C.I. Pigment red 123
  • HY-D2242
    Sulfo-Cy7.5 DBCO
    		99.83%
    Sulfo-Cy7.5 DBCO is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a DBCO group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Sulfo-Cy7.5 DBCO can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
    Sulfo-Cy7.5 DBCO
  • HY-D1883B
    Cy7.5-COOH bromide
    Cy7.5-COOH bromide, a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH bromide can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging.
    Cy7.5-COOH bromide
  • HY-15563
    HOE 33187
    		99.36%
    HOE 33187 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    HOE 33187
  • HY-15626
    ortho-iodoHoechst 33258
    		98.01%
    ortho-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    ortho-iodoHoechst 33258
  • HY-D0108
    Fluorescein dilaurate
    Fluorescein dilaurate is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
    Fluorescein dilaurate
  • HY-W248587
    Cryptocyanine
    		99.15%
    Cryptocyanine is a fluorescent dye.
    Cryptocyanine
  • HY-D0492
    C.I. Basic blue 41
    C.I. Basic blue 41 is an alkaline dye that can be removed from aqueous solutions in intermittent adsorption systems using tree ferns as biosorbents.
    C.I. Basic blue 41
  • HY-D2250
    Disulfo-ICG carboxylic acid
    Disulfo-ICG carboxylic acid is a derivative of ICG dye. ICG (Indocyanine Green) is a NIR fluorescent dye.
    Disulfo-ICG carboxylic acid
  • HY-D2267
    JF646-Hoechst
    JF646-Hoechst is a fluorescent red DNA probe that is an ideal substitute for large oligonucleotide-coupled antibodies used in PAINT experiments, especially for bacterial studies. JF646-Hoechst excitation/emission maximum =655/670 nm.
    JF646-Hoechst
  • HY-D1376
    Sulfo-Cyanine5.5 amine potassium
    Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
    Sulfo-Cyanine5.5 amine potassium
  • HY-126774
    DAF-FM
    		98%
    DAF-FM is a diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance.
    DAF-FM
Cat. No. Product Name / Synonyms Application Reactivity