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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D2299
    AIE-ER
    		98.55%
    AIE-ER is a specific endoplasmic reticulum (ER) fluorescent probe (green channel: λex=405 nm, λem=450~650 nm) that exhibits remarkable photostability, high brightness, and low working concentration. AIE-ER may provide an avenue for studying diseases related to the endoplasmic reticulum.
    AIE-ER
  • HY-D0949
    Pyronine B
    Pyronine B is an organic cationic dye. Pyronin B as a solution-processable and heating-free n-type dopant can be used for soft electronics.
    Pyronine B
  • HY-D2183
    6-Carboxy-JF5252
    6-Carboxy-JF5252 is a fluorophore. 6-Carboxy-JF5252 can be used as probes, dyes, tags. 6-Carboxy-JF5252 can be used for the research of super-resolution imaging.
    6-Carboxy-JF5252
  • HY-P3936
    Endotoxin Substrate
    		99.32%
    Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin.
    Endotoxin Substrate
  • HY-D1883
    Cy7.5-COOH
    Cy7.5-COOH (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging.
    Cy7.5-COOH
  • HY-D2418
    PS-SCOTfluor-12
    PS-SCOTfluor-12 (compound 10) is a fluorescent probe for imaging Lactic acid (HY-B2227) metabolism in live cells. λex/λem= 485/605 nm.
    PS-SCOTfluor-12
  • HY-131682
    3-C6-NBD-cholesterol
    		≥99.0%
    3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking.
    3-C6-NBD-cholesterol
  • HY-D1391
    PbS/CdS QDs
    PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window.
    PbS/CdS QDs
  • HY-138760
    SEluc-2
    SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells.
    SEluc-2
  • HY-D1575
    C6 NBD Galactosylceramide
    C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD). C6 NBD galactosylceramide can be used as a substrate for neutral β-glycosylceramidase (GCase) to study intracellular localization and metabolism of galactosylceramide (Ex=nm, Em=525).
    C6 NBD Galactosylceramide
  • HY-D1432
    FITC-C6-DEVD-FMK
    FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor.
    FITC-C6-DEVD-FMK
  • HY-D2171
    AF488 DBCO
    AF488 DBCO is a fluorescent dye that labels azide-containing biomolecules. DBCO is the bioorthogonal partner of azide that allows covalent coupling in the absence of copper. AF488 is a bright, photostable green fluorophore. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively.
    AF488 DBCO
  • HY-D1568A
    Sulfo-Cy7.5 NHS ester tripotassium
    Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications.
    Sulfo-Cy7.5 NHS ester tripotassium
  • HY-W248118
    Pyrromethene 556
    		99.03%
    Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 556
  • HY-P4323
    Boc-Gln-Arg-Arg-AMC
    Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal.
    Boc-Gln-Arg-Arg-AMC
  • HY-D0376
    Solvent Yellow 93
    		99.11%
    Solvent Yellow 93 (C.I. 48160) is an azomethine dye. Solvent Yellow 93 is used as a colorant of toner. Solvent Yellow 93 is used for the coloring of polyester fiber pulp and is also used to make polyester masterbatch.
    Solvent Yellow 93
  • HY-D1802
    Vari Fluor 425 SE
    Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
    Vari Fluor 425 SE
  • HY-D2096
    Alexa fluor 647 NHS ester
    Alexa fluor 647 NHS ester can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    Alexa fluor 647 NHS ester
  • HY-D1765
    FM 1-43FX
    FM 1-43FX is a fluorescent membrane probe that contains an aliphatic amine which can react with aldehyde-based fixatives.
    FM 1-43FX
  • HY-134145
    1-(Anilinocarbonyl)proline
    		99.60%
    1-(Anilinocarbonyl)proline can be used to identify dual action probes in a cell model of Huntington.
    1-(Anilinocarbonyl)proline
Cat. No. Product Name / Synonyms Application Reactivity