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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-141058
    Cy5-PEG3-azide
    		99.47%
    Cy5-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Cy5-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Cy5-PEG3-azide
  • HY-124197
    Coumarin hydrazine
    Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls.
    Coumarin hydrazine
  • HY-W591768
    (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide
    		99.66%
    (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium (iodide) (Py-NMe2) is a styryl-based dye for fluorescence and CD-based sensing of various ds-DNA/RNA sequence. (maxλAbs = 450 nm, maxλEm = 615 nm).
    (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide
  • HY-W038786
    2,4,6-Trimethylphenol
    		99.98%
    2,4,6-Trimethylphenol is a probe compound shown to react mainly with organic matter (3DOM*). 2,4,6-Trimethylphenol is rapidly oxidized by singlet oxygen in aqueous solution.
    2,4,6-Trimethylphenol
  • HY-D1196
    Direct Blue 71
    Direct Blue 71 is a good dyeing agent for cotton fabrics and can be adsorbed by palm ash and removed from the aqueous solution.
    Direct Blue 71
  • HY-172163C
    FITC-dextran sulfate (MW 500kDa)
    FITC-dextran sulfate, 500kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 500 kDa.
    FITC-dextran sulfate (MW 500kDa)
  • HY-W267364
    Coumarin 343
    Coumarin 343 (C343) is a hydrophilic fluorescent probe for the micro water pool. λem is approximately 425 nm andλem is approximately from 425 nm to 550 nm by RF-1500.
    Coumarin 343
  • HY-50938
    D149 Dye
    D149 Dye is an indoline-based dye, which is a high-extinction-coefficient metal-free organic sensitizer.
    D149 Dye
  • HY-155327B
    Cy3-PEG2-endo-BCN bromide
    Cy3-PEG2-endo-BCN bromide is the bromide salt form of Cy3-PEG2-endo-BCN (HY-155327). Cy3-PEG2-endo-BCN bromide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN bromide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG2-endo-BCN bromide
  • HY-15631
    Hoechst 33258 analog 6
    		99.21%
    Hoechst 33258 analog 6 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution (Ex/Em = 356/451 nm).
    Hoechst 33258 analog 6
  • HY-W009454
    Potassium p-nitrophenyl sulfate
    		98.82%
    p-Nitrophenyl Sulfate Potassium is a chromogenic substrate for arylsulfatase. p-Nitrophenyl Sulfate Potassium is released by arylsulfonase cleavage, and the activity of arylsulfonase can be quantitatively determined by colorimetric detection at 400 nm.
    Potassium p-nitrophenyl sulfate
  • HY-W423080
    TAMRA alkyne,5-isomer
    TAMRA alkyne, 5-isomer (Compound 3) is an alkyne derivative of TAMRA and can be used for the enrichment, in-gel fluorescence detection, and identification of O-GlcNAc-modified proteins. TAMRA alkyne, 5-isomer contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Azide groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    TAMRA alkyne,5-isomer
  • HY-I0259
    8-Amino-2-naphthol
    		≥98.0%
    8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol undergoes excited-state proton transfer (ESPT) to form a zwitterion under acidic conditions, where the photoacidity of its hydroxyl group is regulated by the protonation state of the amino group, enabling pH to act as an on/off switch for photoacidity. 8-Amino-2-naphthol is also utilized as chiral organocatalyst.
    8-Amino-2-naphthol
  • HY-N15351
    Flavokermesic acid
    Flavokermesic acid is an anthraquinone dye found in extracts of insects from the Kermesidae family, where it occurs as a minor pigment component. Flavokermesic acid can be used to study the biosynthetic pathways of insect-derived anthraquinone pigments.
    Flavokermesic acid
  • HY-D1052
    Cy7-YNE
    Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. Cy7-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Cy7-YNE
  • HY-D1042
    1,4-Dichloro 5-carboxytetramethylrhodamine
    		98.00%
    1,4-Dichloro 5-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).
    1,4-Dichloro 5-carboxytetramethylrhodamine
  • HY-D0954
    Jenner's Stain
    Jenner's Stain is a dye that is used in microscopy for staining blood smears. Jenner's Stain can be used for the chromosome stain by C-banding technique. Jenner's Stain can be used for the stain for routine blood examinations and malarial staining.
    Jenner's Stain
  • HY-15619
    Hoechst S 769121
    Hoechst S 769121 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    Hoechst S 769121
  • HY-103594
    2-Aminoacridone
    		99.80%
    2-Aminoacridone is a widely used fluorophore (λexc=428 nm, λem=525 nm).
    2-Aminoacridone
  • HY-D1260
    FM-red
    		98.81%
    FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx).
    FM-red
Cat. No. Product Name / Synonyms Application Reactivity