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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D1574
    C6 NBD Sphingomyelin
    		≥98.0%
    C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane.
    C6 NBD Sphingomyelin
  • HY-D2344
    3-BTD
    		99.49%
    3-BTD (3-Benzothiazole-daphnetin) is a Catechol-O-methyltransferase (COMT) two-photon fluorescence probe. 3-BTD can also be used for biological imaging of endogenous COMT in living cells and tissue sections.
    3-BTD
  • HY-D0110A
    Fura-2 pentapotassium
    Fura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the Kd value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca2+ level.
    Fura-2 pentapotassium
  • HY-P10649A
    CPP12 TFA
    		98.69%
    CPP12 TFA is a small, amphiphilic, cyclic cell-penetrating peptide (CPP) in salt form. CPP12 TFA binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and is then efficiently released from endosomes. CPP12 TFA can be used for intracellular delivery of drugs and chemical probes.
    CPP12 TFA
  • HY-151537
    Gol-NTR
    		99.44%
    Gol-NTR is a Golgi-targetable probe with high selectivity and sensitivity. Gol-NTR is Nitroreductase (NTR)-activated and has visualization acute lung injury (ALI) and repair function. Gol-NTR has a low detection limit of 54.8 ng/mL. Gol-NTR can be used for the research for monitoring and assessing research response of sepsis-induced ALI.
    Gol-NTR
  • HY-103470
    K114
    		≥99.0%
    K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC50 of 20-30 nM. K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).
    K114
  • HY-W127769
    Rose-β-D-Gal
    		99.71%
    Rose-β-D-Gal is a chromogenic substrate, is also a β-galactosidase substrate. Rose-β-D-Gal creates a pink/magenta color after the reaction and has been used for detection of β-gal activity.
    Rose-β-D-Gal
  • HY-D0805
    Eosin 5-isothiocyanate
    Eosin 5-isothiocyanate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Eosin 5-isothiocyanate
  • HY-W127716
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs).
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
  • HY-W269179
    4-Bromomethyl-6,7-dimethoxycoumarin
    		99.21%
    4-Bromomethyl-6,7-dimethoxycoumarin is a fluorescent label for carboxylic acids in chromatographic detection.
    4-Bromomethyl-6,7-dimethoxycoumarin
  • HY-D0219
    Thymol blue
    Thymol blue is a reversible pH indicator that responds to the pH of the solution through structural changes of protonation and deprotonation. Thymol blue is red (HI- form) under acidic conditions and blue (I2- form) under alkaline conditions. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue selectively responds to pH changes, changing from red to yellow at pH 1.2-2.8 and from yellow to blue at pH 8.0-9.6. Thymol blue can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field[1][2].
    Thymol blue
  • HY-D1198
    Eosin B
    Eosin B (Acid Red 91) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Eosin B
  • HY-D0016
    5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride
    		98.06%
    5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride (CTC) is a redox-sensitive red fluorescent dye. 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride can be used for detecting metabolic activity in microorganisms. The emission maximum of 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride is 602 nm.
    5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride
  • HY-149203A
    MQA-P TFA
    MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO-, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO-, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images.
    MQA-P TFA
  • HY-D1302
    Near-IR fluorescent probe-1
    Near-IR fluorescent probe-1 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Near-IR fluorescent probe-1
  • HY-149618
    Cy5-PEG3-endo-BCN
    		98.40%
    Cy5-PEG3-endo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy5-PEG3-endo-BCN
  • HY-15935C
    X-Gluc sodium
    		≥98.0%
    X-Gluc sodium is a dye reagent for the detection of β-glucuronidase (GUS), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract (GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene, appears blue).
    X-Gluc sodium
  • HY-145383
    Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide
    Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is a clickable, acid-cleavable biotin-picolyl azide. Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is an enrichment handle of cell surface glycoproteins for protein labeling. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide
  • HY-D1677
    5(6)-Carboxynaphthofluorescein
    5(6)-Carboxynaphthofluorescein is a pH-dependent fluorophore. 5(6)-Carboxynaphthofluorescein shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. 5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator (Ex/Em=593/668 nm).
    5(6)-Carboxynaphthofluorescein
  • HY-136213
    Endoplasmic reticulum dye 1
    		99.63%
    Endoplasmic reticulum dye 1 is a promising live cell imaging agent for the detection of exocytotic events at the plasma membrane. Endoplasmic reticulum dye 1 shows low cytotoxicity, resistance to photobleaching , which is ideal for imaging either short- or long-time courses.
    Endoplasmic reticulum dye 1
Cat. No. Product Name / Synonyms Application Reactivity