2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1527):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W020246
    Tetramethylthiuram monosulfide
    		99.71%
    Tetramethylthiuram monosulfide (TMTM) is an active compound. Tetramethylthiuram monosulfide (TMTM) can be used for the research of rubber and various biochemical studies.
    Tetramethylthiuram monosulfide
  • HY-114591
    Spiromesifen
    Spiromesifen (BSN 2060) is a broad-spectrum tetrachloro acid derivative acaricide. Spiromesifen reduces lipid biosynthesis via inhibition of acetyl-CoA carboxylase, and has no cross-resistance to any resistant mite or whitefly populations.
    Spiromesifen
  • HY-117109
    Amino Tadalafil
    		99.04%
    Amino Tadalafil is a structural analogue of Tadalafil (HY-90009A). Tadalafil is a potent inhibitor of PDE5 with applications in several conditions, including erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.
    Amino Tadalafil
  • HY-76701
    4-Nitrothalidomide
    		99.01%
    4-Nitrothalidomide is a nitrosylated Thalidomide analogue. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
    4-Nitrothalidomide
  • HY-W004292
    1-Undecanol
    		99.79%
    1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps.
    1-Undecanol
  • HY-133860
    Chrysoobtusin
    		99.43%
    Chrysoobtusin is an anthraquinone derivative isolated from Semen Cassiae. Semen Cassiae has long been used to protect liver, brighten eyes, and relieve constipation.
    Chrysoobtusin
  • HY-W072385
    1,2-Dibromo-4,5-methylenedioxybenzene
    		99.82%
    1,2-Dibromo-4,5-methylenedioxybenzene is an impurity in the synthesis of amphetamines.
    1,2-Dibromo-4,5-methylenedioxybenzene
  • HY-W013330
    3′-Deoxyguanosine
    3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a derivative of Guanosine (HY-N0097). 3′-Deoxyguanosine interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. 3′-Deoxyguanosine exhibits moderate displacement activity for [3H]-guanosine in rat meninges. 3′-Deoxyguanosine is useful for studying the mechanism of guanosine receptors and purine metabolism.
    3′-Deoxyguanosine
  • HY-126126
    S-Adenosyl-DL-methionine
    		99.84%
    S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of methionine.
    S-Adenosyl-DL-methionine
  • HY-34611
    Boc-L-2,4-Diaminobutyric acid
    		≥98.0%
    Boc-L-2,4-Diaminobutyric acid is a derivative of L-2,4-Diaminobutyric acid (HY-101414)[1.
    Boc-L-2,4-Diaminobutyric acid
  • HY-111178
    Lauflumide
    		99.89%
    Lauflumide (BisfluoroModafinil) is the common alternative of modafinil. Modafinil is commonly prescribed for the research narcolepsy. Lauflumide has the potential for cognitive enhancing.
    Lauflumide
  • HY-164165
    Paclitaxel-2′-succinate NHS ester
    		98.78%
    Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy.
    Paclitaxel-2′-succinate NHS ester
  • HY-137905
    Pomalidomide-amido-C5-PEG2-C6-chlorine
    		99.69%
    Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivant of Pomalidomide (HY-10984).
    Pomalidomide-amido-C5-PEG2-C6-chlorine
  • HY-W002450
    L-Cyclohexylalanine
    		≥98.0%
    L-Cyclohexylalanine is an amino acid derivative. L-Cyclohexylalanine modifies an atrial natriuretic peptide, regulates homeostasis of body fluid and blood pressure homeostasis and vasodilation activity.
    L-Cyclohexylalanine
  • HY-145967A
    (R)-FT709
    (R)-FT709 is an active compound. (R)-FT709 can be used for the research of cancers.
    (R)-FT709
  • HY-W039116
    Thalidomide-4-Br
    		99.70%
    Thalidomide-4-Br (compound 53) is a compound with a bromodomain. Thalidomide-4-Br can be used in the research of inflammation, tumor and neurology.
    Thalidomide-4-Br
  • HY-B1061
    Nicotinic acid N-oxide
    		99.92%
    Nicotinic acid N-oxide can be used for research on hyperlipidemia.
    Nicotinic acid N-oxide
  • HY-W007364
    m-Iodophenol
    		99.89%
    m-Iodophenol is a protaetia brevitarsis attractant.
    m-Iodophenol
  • HY-U00153
    Dixyrazine
    		99.87%
    Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate.
    Dixyrazine
  • HY-34887
    Acridone-4-carboxylic acid
    		98.69%
    Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM.
    Acridone-4-carboxylic acid