2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1528):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y1777
    2-Phenylacetophenone
    		99.96%
    2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity. 2-Phenylacetophenone is a benzoin derivative used as a photoinitiator in vinyl polymerization.
    2-Phenylacetophenone
  • HY-146748
    Sorbicillin
    		99.69%
    Sorbicillin, a sorbicillinoid analogue, acts as a potent anti-inflammation agent.
    Sorbicillin
  • HY-131501
    Menaquinone 9
    		98.0%
    Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase.
    Menaquinone 9
  • HY-126247B
    (R)-BI-2852
    (R)-BI-2852 is the isomer of BI-2852 (HY-126247), and can be used as an experimental control. BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) by structure-based agent design with nanomolar affinity. BI-2852 is mechanistically distinct from covalent KRASG12C inhibitor (binds to switch II pocket) and binds ten-fold more strongly to active KRASG12D versus KRASwt (740 nM vs 7.5 μM). BI-2852 blocks GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
    (R)-BI-2852
  • HY-131116
    Dihydrojasmonic acid
    		99.26%
    Dihydrojasmonic acid is a plant growth regulator.
    Dihydrojasmonic acid
  • HY-W017100
    2-Hydroxy-6-methoxybenzoic acid
    		99.34%
    2-Hydroxy-6-methoxybenzoic acid (6-Methoxysalicylic acid) is an orally active derivative of Salicylic acid (HY-B0167). 2-Hydroxy-6-methoxybenzoic acid can be isolated from the plant Brickellia veronicifolia. 2-Hydroxy-6-methoxybenzoic acid has analgesic properties.
    2-Hydroxy-6-methoxybenzoic acid
  • HY-139093A
    Paracetamol-cysteine TFA
    		99.0%
    Paracetamol-cysteine (TFA) is an acetaminophen-protein adduct formed during the metabolism of acetaminophen (HY-66005).
    Paracetamol-cysteine TFA
  • HY-133513
    (±)-H3RESCA-TFP
    		98.15%
    (±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine).
    (±)-H3RESCA-TFP
  • HY-W588263
    Indole-3-acetyl glutamate
    		99.68%
    Indole-3-acetyl glutamate (IAGlu) is a derivative of the plant hormone indole-3-acetic acid (IAA). As a conjugated form of IAA, Indole-3-acetyl glutamate involves in the transport, storage, and homeostatic regulation of IAA within the plant. Indole-3-acetyl glutamate can be used for research into the effects of plant hormones on the growth and development of plants.
    Indole-3-acetyl glutamate
  • HY-Z11724
    Semaglutide Main Chain (9-37)
    		99.62%
    Semaglutide Main Chain (9-37) is a peptide starting material in the synthesis of semaglutide (HY-114118).
    Semaglutide Main Chain (9-37)
  • HY-B1044
    Idramantone
    		99.94%
    Idramantone (Kemantane, 5-Hydroxy-2-adamantanone) is an Adamantane derivative. Idramantone is an immunostimulant. Idramantone is a versatile starting material for the synthesis of various adamantine deivatives. Idramantone can be produced using P450cam monooxygenase coupled with NADH regeneration as an oxidation biocatalyst. Idramantone can be studied in research on bronchial pathology.
    Idramantone
  • HY-122365
    Inositol nicotinate
    		98.05%
    Inositol nicotinate (Hexanicit) has vasodilating effects and can be used in research on peripheral arterial disease, showing efficacy when taken orally. Inositol nicotinate does not significantly improve triglyceride levels in mice induced by biphenyl esters.
    Inositol nicotinate
  • HY-139167
    7-Hydroxywarfarin
    		99.39%
    7-Hydroxywarfarin is a Warfarin analog with anticoagulant activity.
    7-Hydroxywarfarin
  • HY-N7138
    2-(Phosphonooxy)benzoic acid
    2-(Phosphonooxy)benzoic acid is a non-acetylated salicylic acid derivative which has the potential for inflammatory disease as well as in analgesic therapy.
    2-(Phosphonooxy)benzoic acid
  • HY-120784
    Hexafluoro-diallylhexaflurobisphenol
    Hexafluoro-diallylhexaflurobisphenol is a Honokiol analogue (HA). Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules.
    Hexafluoro-diallylhexaflurobisphenol
  • HY-133597
    4-Chlorocatechol
    		99.37%
    4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase.
    4-Chlorocatechol
  • HY-141630
    Sphingosine-1-phosphate (d17:1)
    		99.00%
    Sphingosine-1-phosphate d17:1 (D-erythro-Sphingosine-C17-1-phosphate) is a derivative of ceramide. Sphingosine-1-phosphate d17:1 can be used for the research of cancer.
    Sphingosine-1-phosphate (d17:1)
  • HY-W506071
    3,7-Dimethyluric acid
    3,7-Dimethyluric acid is a methyl derivative of uric acid.
    3,7-Dimethyluric acid
  • HY-N10991
    Crocetin dialdehyde
    		99.21%
    Crocetin dialdehyde is a non-volatile apocarotenoid obtained by the action of the plastidic enzyme CCD2 over the carotenoid zeaxanthin in saffron. Crocetin dialdehyde can be converted into Crocetin (HY-N2072) by aldehyde dehydrogenases (ALDHs). Crocetin dialdehyde has no effect on the liver in mice.
    Crocetin dialdehyde
  • HY-W001084
    Methyl 4-hydroxyphenylacetate
    		99.95%
    Methyl 4-hydroxyphenylacetate, a natural compound, is a methyl ester resulting from the formal condensation of the carboxy group of 4-Hydroxyphenylacetic acid with methanol.
    Methyl 4-hydroxyphenylacetate