2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1652):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-136554
    WYC-210
    		99.18%
    WYC-210, a Tazarotene derivative, is a retinoid compound with lower anticancer activity. WYC-210 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    WYC-210
  • HY-173374
    DOTAGA-FAP-2286-ALB
    DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability (e.g., with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors.
    DOTAGA-FAP-2286-ALB
  • HY-121469
    Dioxone
    		98.0%
    Dioxone is a substance possessing convulsant properties qualitatively similar to leptazol and bemegride. Dioxone is orally active.
    Dioxone
  • HY-177267
    Camptothecin derivative-3
    Camptothecin derivative-3 (Compound 11) is a derivative of Camptothecin (HY-16560) and can serve as a payload for ADCs. Camptothecin derivative-3 has certain cytotoxicity, with IC50 values of 2 nM and 0.9 nM against HSC-2 and Namalwa/luc cells, respectively. Camptothecin derivative-3 can be used in tumor-related research.
    Camptothecin derivative-3
  • HY-W197713
    2-Amino-N-phenylpropanamide hydrochloride
    		≥99.0%
    2-Amino-N-phenylpropanamide (Compound 5b) hydrochloride is a Tocainid (HY-B1798) analog. Tocainid is an antiarrythmic agent.
    2-Amino-N-phenylpropanamide hydrochloride
  • HY-148205A
    Trypanothione TFA
    Trypanothione (TFA) is a bis-glutathionyl derivative, found in trypanosomatids. Trypanothione (TFA) itself or assisted by different enzymatic systems is involved in anti-oxidant defense, cell proliferation, removal of toxic compounds and metabolites and iron-sulfur metabolism.
    Trypanothione TFA
  • HY-P1157
    Exendin derivative 1
    		98.94%
    Exendin derivative 1 is a 39 amino acid peptide.
    Exendin derivative 1
  • HY-124669
    RTC-30
    		99.13%
    RTC-30 is an optimized phenothiazine with anti-cancer potency. RTC-30 contains a hydroxylated linker (N) that confers increased oral bioavailability.
    RTC-30
  • HY-122477
    Zylofuramine
    		99.92%
    Zylofuramine is a psychomotor stimulant. Zylofuramine can be used in the research related to appetite suppressants and Alzheimer's disease.
    Zylofuramine
  • HY-U00148
    KY-556
    		98.59%
    KY-556 is a promising and orally-active pro-agent of disodium cromoglycate (DSCG) against allergic diseases.
    KY-556
  • HY-121770
    Rutarin
    		99.84%
    Rutarin is a Coumarin (HY-N0709) derivative with antimalarial and antifungal activities. Rutarin inhibits Plasmodium falciparum with an IC50 of 88 μg/mL. Rutarin also inhibits Coniophora cerebella.
    Rutarin
  • HY-130791
    Dioctanoin
    		99.9%
    Dioctanoin is a type of diacylglycerol.
    Dioctanoin
  • HY-120255
    17(R)-HDHA
    		98.0%
    17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells.
    17(R)-HDHA
  • HY-P3218A
    [Glu4]-Oxytocin acetate
    		99.47%
    [Glu4]-Oxytocin acetate is an appropriate derivative of oxytocin for conducting a comprehensive investigation by a variety of methods of the conformation of oxytocin-like molecules in aqueous solution.
    [Glu4]-Oxytocin acetate
  • HY-136171
    Antidepressant agent 1
    		98.84%
    Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. Antidepressant agent 1 also can be used to increase body temperature.
    Antidepressant agent 1
  • HY-W004288S
    Methyl tetradecanoate-d27
    		99.0%
    Methyl tetradecanoate-d27 is the deuterium labeled Methyl myristate. Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma.
    Methyl tetradecanoate-d<sub>27</sub>
  • HY-U00274
    Ropitoin
    		98.16%
    Ropitoin (TR 2985) is a novel antiarrhythmic agent.
    Ropitoin
  • HY-106873
    Nepinalone
    Nepinalone, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity.
    Nepinalone
  • HY-153552
    NH2-UAMC1110
    NH2-UAMC1110 is a UAMC1110 (HY-100684) derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors.
    NH2-UAMC1110
  • HY-137951
    Metizolam
    		99.30%
    Metizolam, a thienotriazolodiazepine, is the demethylated analogue of Etizolam. Metizolam exhibits psychomotor stabilizing, anxiolytic, sedative, myo-relaxant and amnestic effects.
    Metizolam