Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1619):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W041983

Fmoc-Cpa-OH		99.85%
Fmoc-Cpa-OH is a compound containing both an amino group and a carboxyl group.

HY-22062

Fmoc-Chg-OH		99.98%
Fmoc-Chg-OH is a Glycine (HY-Y0966) derivative.

HY-W008021

Fmoc-D-Leu-OH		99.99%
Fmoc-D-Leu-OH is a leucine derivative.

HY-W007655

Fmoc-D-Lys(Boc)-OH		99.87%
Fmoc-D-Lys (Boc)-OH is a protected D-lysine derivative with an Fmoc group protecting the amino group and a Boc group protecting the side chain. Fmoc-D-Lys (Boc)-OH ensures the accurate integration of D-lysine into the peptide chain, maintaining the peptide's specific conformation and biological activity. Fmoc-D-Lys (Boc)-OH can be used in the synthesis of peptides containing unnatural amino acids.

HY-W040804

2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride		99.51%
2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride is an alanine derivative.

HY-137875

Hippuryl-His-Leu-OH hydrate		99.65%
Hippuryl-His-Leu-OH (N-Benzoyl-Gly-His-Leu) hydrate is a substrate for detecting the activity of angiotensin I converting enzyme. The His-Leu released by Hippuryl-His-Leu-OH hydrate can react with o-phtbaldialdehyde or Fluorescamine (HY-D0715) for fluorescence detection.

HY-W011000

Fmoc-Cha-OH		99.50%
Fmoc-Cha-OH is an alanine derivative.

HY-W013726

Fmoc-Phe(4-Br)-OH		99.83%
Fmoc-Phe(4-Br)-OH is a widely used amino acid derivative. Fmoc-Phe(4-Br)-OH can be used in the synthesis of compounds and for the study of protein-protein interactions and the development of biomaterials. Fmoc-Phe(4-Br)-OH can be used in peptide synthesis to incorporate phenylalanine bromide into the peptide chain.

HY-79877

Boc-Ser(Tos)-OMe		≥99.0%
Boc-Ser(Tos)-OMe is a serine derivative.

HY-W014919

H-Phe(2-Cl)-OH		99.92%
H-Phe(2-Cl)-OH is a phenylalanine derivative.

HY-20561

N-Methyl-L-valine		98.0%
N-Methyl-L-valine is a valine derivative.

HY-W018849

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2,3-dimethylbutanoic acid		99.92%
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2,3-dimethylbutanoic acid is a valine derivative.

HY-113286

4-Guanidinobutanoic acid		98.0%
4-Guanidinobutanoic acid is a common urinary metabolite and arginine metabolite. 4-Guanidinobutanoic acid can be used in the research of fibromyalgia.

HY-W011056

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(furan-2-yl)propanoic acid		99.66%
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(furan-2-yl)propanoic acid is an alanine derivative.

HY-W008971

Fmoc-Phe(4-Cl)-OH		99.80%
Fmoc-Phe(4-Cl)-OH is a phenylalanine derivative.

HY-20897A

5-Bromo-L-tryptophan		99.60%
5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236).

HY-W008446

(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid		99.80%
(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid is a proline derivative.

HY-139666

N-Palmitoyl-L-glutamine		99.88%
N-Palmitoyl-L-glutamine is a Glutamine derivative.

HY-W048217

N6-Butyryl-L-lysine		99.98%
N6-Butyryl-L-lysine is a lysine derivative.

HY-79106

L-Biphenylalanine		99.95%
L-Biphenylalanine is a phenylalanine derivative.

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