2. Signaling Pathways
  3. Others
  4. Amino Acid Derivatives

Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

Amino Acid Derivatives Related Products (1564):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W008086A
    (Rac)-H-Thr-OMe hydrochloride
    (Rac)-H-Thr-OMe hydrochloride is the isomer of H-Thr-OMe hydrochloride (HY-W008086), and can be used as an experimental control. H-Thr-OMe.HCl is a threonine derivative.
    (Rac)-H-Thr-OMe hydrochloride
  • HY-P2402
    Fmoc-Gly-Thr(psi(Me,Me)pro)-OH
    		99.30%
    Fmoc-Gly-Thr(psi(Me,Me)pro)-OH is a dipeptide.
    Fmoc-Gly-Thr(psi(Me,Me)pro)-OH
  • HY-168772
    Glycyl-L-Proline TFA
    Glycyl-L-Proline TFA (H-Gly-Pro-OH TFA) is a dipeptide, which is composed of a glycine and a L-proline. Glycyl-L-Proline TFA can be used in research about the co-relationship between transmembrane potential/proton gradient and intestinal transport.
    Glycyl-L-Proline TFA
  • HY-103664A
    Fmoc-1,6-diaminohexane hydrochloride
    Fmoc-1,6-diaminohexane hydrochloride is the hydrochloride form of Fmoc-1,6-diaminohexane (HY-103664). Fmoc-1,6-diaminohexane hydrochloride conjugates with monoclonal antibody, and exhibits anticancer activity against p21-deficient cancer.
    Fmoc-1,6-diaminohexane hydrochloride
  • HY-W423573
    N,S-Diacetylcysteine methyl ester
    N,S-Diacetylcysteine ​​methyl ester is a cysteine ​​derivative that can increase the levels of intracellular cysteine ​​and glutathione. N,S-Diacetylcysteine ​​methyl ester is hydrolyzed by intracellular esterase to release cysteine, thereby promoting the synthesis of glutathione. Due to its acetylation properties, N,S-Diacetylcysteine ​​methyl ester has better cell membrane permeability and can enter the cell more effectively. N,S-Diacetylcysteine ​​methyl ester can be used to study the intracellular cysteine ​​and glutathione (GSH) transport system.
    N,S-Diacetylcysteine methyl ester
  • HY-W141814
    Boc-D-Pen(Mob)-OH
    Boc-D-Pen(Mob)-OH is a phenylalanine derivative.
    Boc-D-Pen(Mob)-OH
  • HY-17490S
    Oxaceprol-d3
    Oxaceprol-d3 (N-Acetyl-L-hydroxyproline-d3) is deuterium labeled Oxaceprol. Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis.
    Oxaceprol-d<sub>3</sub>
  • HY-W722107
    Timonacic-d4
    Timonacic-d4 (1,3-Thiazolidine-4-carboxylic acid-d4) is deuterium labeled Timonacic. Timonacic (1,3-Thiazolidine-4-carboxylic acid) is a thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects, and it can be used to study acute illnesses and liver diseases, by inducing reversal, it is also used in research on certain cancer cases.
    Timonacic-d<sub>4</sub>
  • HY-W013678R
    H-Glu(OMe)-OH (Standard)
    H-Glu(OMe)-OH (Standard) is the analytical standard of H-Glu(OMe)-OH. This product is intended for research and analytical applications. H-Glu(OMe)-OH is a glutamic acid derivative.
    H-Glu(OMe)-OH (Standard)
  • HY-59135R
    (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid (Standard)
    (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid (Standard) is the analytical standard of (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid. This product is intended for research and analytical applications. (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid is a leucine derivative.
    (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid (Standard)
  • HY-B1258S
    Intermediate of tranexamic Acid-13C2,15N
    Intermediate of tranexamic Acid-13C2,15N (Aminomethylbenzoic acid-13C2,15N) is 13C and 15N labeled 4-(Aminomethyl)benzoic acid. 4-(Aminomethyl)benzoic acid is a competitive inhibitor of PepT1 and has antifibrinolytic activity.
    Intermediate of tranexamic Acid-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N<sub>
  • HY-W013998S
    Glycyl-L-phenylalanine-d2
    Glycyl-L-phenylalanine-d2 is a deuterium labeled Glycyl-L-phenylalanine (HY-W013998). Glycyl-L-phenylalanine is a phenylalanine derivative.
    Glycyl-L-phenylalanine-d<sub>2</sub>
  • HY-111592S
    S-(5′-Adenosyl)-L-cysteine-13C
    S-(5′-Adenosyl)-L-cysteine-13C is the 13C labeled S-(5′-Adenosyl)-L-cysteine (HY-111592). S-(5′-Adenosyl)-L-cysteine is a cysteine derivative.
    S-(5′-Adenosyl)-L-cysteine-<sup>13</sup>C
  • HY-101877R
    Statine (Standard)
    Statine (Standard) is the analytical standard of Statine. This product is intended for research and analytical applications. Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases.
    Statine (Standard)
  • HY-157248
    Fmoc-3-Me-Glu(OtBu)-OH
    Fmoc-3-Me-Glu(OtBu)-OH is an amino acid derivative with a protective group.
    Fmoc-3-Me-Glu(OtBu)-OH
  • HY-W141899
    4-(Trifluoromethyl)-L-phenylglycine
    4-(Trifluoromethyl)-L-phenylglycine is a Glycine (HY-Y0966) derivative.
    4-(Trifluoromethyl)-L-phenylglycine
  • HY-W844796
    2-Amino-5-methyl-5-hexenoic acid
    2-Amino-5-methyl-5-hexenoic acid ((S)-2-Amino-5-methylhex-5-enoic acid) is a Methionine analog that competes with methionine and resulting in inhibition of cell growth. 2-Amino-5-methyl-5-hexenoic acid inhibits protein synthesis but not DNA or RNA synthesis in S. typhimurium TA1535 and E. coli K-12. X
    2-Amino-5-methyl-5-hexenoic acid
  • HY-P4551
    Hippuryl-His-Leu-OH
    Hippuryl-His-Leu-OH (N-Benzoyl-Gly-His-Leu) is a substrate for detecting the activity of angiotensin I converting enzyme. The His-Leu released by Hippuryl-His-Leu-OH can react with o-phtbaldialdehyde or Fluorescamine (HY-D0715) for fluorescence detection.
    Hippuryl-His-Leu-OH
  • HY-104004A
    Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH
    Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative.
    Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH
  • HY-137025
    (S)-NIFE
    (S)-NIFE is a chiral derivatizing agent for proteinogenic amino acid analysis.
    (S)-NIFE