Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W048217

N6-Butyryl-L-lysine		99.98%
N6-Butyryl-L-lysine is a lysine derivative.

HY-W010982

Fmoc-Phe(4-NH2)-OH		98.98%
Fmoc-Phe(4-NH2)-OH is a phenylalanine derivative.

HY-79877

Boc-Ser(Tos)-OMe		≥99.0%
Boc-Ser(Tos)-OMe is a serine derivative.

HY-W009119

Fmoc-D-Val-OH		99.88%
Fmoc-D-Val-OH is a valine derivative.

HY-W008196

H-Lys(Fmoc)-OH		99.39%
H-Lys(Fmoc)-OH is a lysine derivative.

HY-W007056

Fmoc-N-me-Trp(Boc)-OH		99.70%
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa.

HY-W041983

Fmoc-Cpa-OH		99.85%
Fmoc-Cpa-OH is a compound containing both an amino group and a carboxyl group.

HY-W008021

Fmoc-D-Leu-OH		99.99%
Fmoc-D-Leu-OH is a leucine derivative.

HY-P1851A

AGA-(C8R) HNG17, humanin derivative TFA		98.34%
AGA-(C8R) HNG17, humanin derivative TFA is a potent humanin (HN) derivative. AGA-(C8R) HNG17, humanin derivative completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.

HY-W097054

Fmoc-L-cysteic acid
Fmoc-L-cysteic acid is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize triarylsulfonium compounds for radiolabeling of peptides.

HY-W008971

Fmoc-Phe(4-Cl)-OH		99.80%
Fmoc-Phe(4-Cl)-OH is a phenylalanine derivative.

HY-32688

Boc-Ser-OMe		99.11%
Boc-Ser-OMe is a serine derivative.

HY-W008560

Fmoc-Gly(allyl)-OH		99.94%
Fmoc-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative.

HY-W008029

H-Lys(Z)-OtBu.HCl		99.93%
H-Lys(Z)-OtBu.HCl is a lysine derivative.

HY-W009124

Fmoc-D-Pro-OH		99.97%
Fmoc-D-Pro-OH is a proline derivative.

HY-114348

N,N'-Diacetyl-L-cystine		98.92%
N,N'-diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine is a potent, orally active modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits.

HY-W011000

Fmoc-Cha-OH		99.50%
Fmoc-Cha-OH is an alanine derivative.

HY-W141858

N-(3-Indolylacetyl)-L-alanine		99.91%
N-(3-Indolylacetyl)-L-alanine (Indoleacetylalanine) is an indoleacetylamino acid. N-(3-Indolylacetyl)-L-alanine appears to increase callus growth and reduces the ability of growths to differentiate into shoots of Phalaenopsis orchids.

HY-W008558

Fmoc-N-Me-Leu-OH		99.36%
Fmoc-N-Me-Leu-OH, an N-Fmoc-N-methyl amino acid, is available for the peptide-coupling reaction.

HY-W022223

Fmoc-3-Chloro-L-phenylalanine		98.97%
Fmoc-3-Chloro-L-phenylalanine is a phenylalanine derivative.

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