2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W612372
    4-(Bromomethyl)benzenesulfonyl fluoride
    4-(Bromomethyl)benzenesulfonyl fluoride (Fluorosulfonylbenzyl bromide) is an important chemical reagent with good biological activity. 4-(Bromomethyl)benzenesulfonyl fluoride can be used to prepare various bioactive molecules, especially in the process of compound discovery and synthesis, showing excellent reactivity. 4-(Bromomethyl)benzenesulfonyl fluoride is often used in the development of new biological agents, promoting the research progress of organic chemistry and biochemistry.
    4-(Bromomethyl)benzenesulfonyl fluoride
  • HY-W019704R
    N-Acetyl-DL-methionine (Standard)
    N-Acetyl-DL-methionine (Standard) is the analytical standard of N-Acetyl-DL-methionine. This product is intended for research and analytical applications. N-Acetyl-DL-methionine is an endogenous metabolite.
    N-Acetyl-DL-methionine (Standard)
  • HY-N0148AR
    Rutin hydrate (Standard)
    Rutin (hydrate) (Standard) is the analytical standard of Rutin (hydrate). This product is intended for research and analytical applications. Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress.
    Rutin hydrate (Standard)
  • HY-113073
    2,4-Dihydroxybutanoic acid
    2,4-Dihydroxybutanoic acid is typically absent in normal human urine extracts and is found only in trace amounts in neonates, while cases of succinic semialdehyde dehydrogenase deficiency consistently exhibit elevated levels of this metabolite.
    2,4-Dihydroxybutanoic acid
  • HY-172731
    8-Oxo-dATP lithium
    8-Oxo-dATP lithium, as an oxidized purine nucleoside triphosphate, is hydrolyzed by MTH1 into monophosphates, thereby preventing errors caused by its misincorporation during DNA replication or transcription.
    8-Oxo-dATP lithium
  • HY-110013A
    (Rac)-Terreic acid
    (Rac)-Terreic acid is a natural product that has the activity of inhibiting mitotic kinase 8. (Rac)-Terreic acid can be used as a potential bioactive molecule to participate in the regulation of cell signaling. (Rac)-Terreic acid has shown effects on cell proliferation and cell survival in research.
    (Rac)-Terreic acid
  • HY-14649S2
    11-cis-Retinoic Acid-d5
    11-cis-Retinoic Acid-d5 is the deuterium labeled Retinoic acid. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2].
    11-cis-Retinoic Acid-d<sub>5</sub>
  • HY-169449
    16-Carboxymitragynine
    16-Carboxymitragynine is a metabolite of mitragynine.
    16-Carboxymitragynine
  • HY-W040313
    2-(Undecyloxy)ethanol
    		99.05%
    2-(Undecyloxy)ethanol is a pheromone that can be produced by the male Monochamus alternatus Hope.
    2-(Undecyloxy)ethanol
  • HY-128417S1
    Alpha-D-glucose-13C
    		99.4%
    Alpha-D-glucose-13C is the 13C labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite.
    Alpha-D-glucose-<sup>13</sup>C
  • HY-B0225R
    Methyldopa (Standard)
    Methyldopa (Standard) is the analytical standard of Methyldopa. This product is intended for research and analytical applications. Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system.
    Methyldopa (Standard)
  • HY-107826R
    5α-Cholestan-3-one (Standard)
    5α-Cholestan-3-one (Standard) is the analytical standard of 5α-Cholestan-3-one. This product is intended for research and analytical applications. 5α-Cholestan-3-one is an endogenous metabolite.
    5α-Cholestan-3-one (Standard)
  • HY-122129S
    Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d6
    Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d6 is deuterium labeled Dotriaconta-14,17,20,23,26,29-hexaenoic acid. Very long chain polyunsaturated fatty acids (VLCPUFA) are present in retina, sperm, and brain. Though little is known of their biosynthesis or functional roles in these tissues, recent studies using the elongation of very long-chain FA-4 protein suggest a unique role for VLCPUFA in retinal development and macular degeneration. Dotriaconta-14,17,20,23,26,29-hexaenoic acid is a C32:6 VLCPUFA whose specific biological actions are largely unknown, but are thought to involve normal photoreceptor cell function in the retina.
    Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d<sub>6</sub>
  • HY-116083
    13,14-Dihydro-15-keto-tetranor prostaglandin D2
    13,14-Dihydro-15-keto-tetranor prostaglandin D2 (Compound VI) is a prostaglandin D2 metabolite. 13,14-Dihydro-15-keto-tetranor prostaglandin D2 as a biomarker can be used to study prostaglandin D2-related diseases.
    13,14-Dihydro-15-keto-tetranor prostaglandin D2
  • HY-W015560R
    3,5-Dihydroxybenzoic acid (Standard)
    3,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 3,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses. 3,5-Dihydroxybenzoic acid is the agonist for hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) that inhibits lipolysis in adipocytes. 3,5-Dihydroxybenzoic acid is the competitive inhibitor for tyrosine phenol-lyase (TPL), exhibits an affinity of Ki=25.7 μM. 3,5-Dihydroxybenzoic acid is orally active.
    3,5-Dihydroxybenzoic acid (Standard)
  • HY-B2233BR
    Phosphorylcholine (Standard)
    Phosphorylcholine (Standard) is the analytical standard of Phosphorylcholine. This product is intended for research and analytical applications. Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties.
    Phosphorylcholine (Standard)
  • HY-W004515R
    3-Pyridylacetic acid hydrochloride (Standard)
    3-Pyridylacetic acid (hydrochloride) (Standard) is the analytical standard of 3-Pyridylacetic acid (hydrochloride). This product is intended for research and analytical applications. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids).
    3-Pyridylacetic acid hydrochloride (Standard)
  • HY-N0076R
    Bilobalide (Standard)
    Bilobalide (Standard) is the analytical standard of Bilobalide. This product is intended for research and analytical applications. Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons.
    Bilobalide (Standard)
  • HY-P1032S
    Angiotensin I-13C19,15N3 (human, mouse, rat)
    Angiotensin I-13C19,15N3 (human, mouse, rat) is the 13C and 15N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food.
    Angiotensin I-<sup>13</sup>C<sub>19</sub>,<sup>15</sup>N<sub>3</sub> (human, mouse, rat)
  • HY-137980
    Carbonate ionophore VII
    Carbonate ionophore VII is primarily utilized in the fabrication of ion-selective electrodes.
    Carbonate ionophore VII
Cat. No. Product Name / Synonyms Application Reactivity