2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-101981S4
    Uridine 5'-monophosphate-13C9 dilithium
    Uridine 5'-monophosphate-13C9 (5'- Uridylic acid-13C9) dilithium is 13C-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'- Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
    Uridine 5'-monophosphate-<sup>13</sup>C<sub>9</sub> dilithium
  • HY-E70325
    Maltogenic amylase
    Maltogenic amylase is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible.
    Maltogenic amylase
  • HY-N8400
    Roridin L2
    Roridin L2, a fungal metabolite, is a biosynthetic precursor of Satratoxin G. Roridin L2 possesses little in vitro or in vivo toxic activity.
    Roridin L2
  • HY-113263S1
    17α-Hydroxypregnenolone-13C2,d2
    17α-Hydroxypregnenolone-13C2,d2 is the deuterium and 13C labeled 17α-Hydroxypregnenolone.
    17α-Hydroxypregnenolone-<sup>13</sup>C<sub>2</sub>,d<sub>2</sub>
  • HY-N0083G
    Betulin (GMP)
    Betulin (GMP) (Trochol (GMP)) is Betulin (HY-N0083) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.
    Betulin (GMP)
  • HY-B0502AR
    Enrofloxacin monohydrochloride (Standard)
    Enrofloxacin (monohydrochloride) (Standard) is the analytical standard of Enrofloxacin (monohydrochloride). This product is intended for research and analytical applications. Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV).
    Enrofloxacin monohydrochloride (Standard)
  • HY-176431
    TLCD1-IN-1
    		Inhibitor
    TLCD1-IN-1 (compound MB-4A) is a covalent TLCD1 inhibitor. TLCD1-IN-1 stereoselectively engages and inhibits TLCD1 in HepG2 cells.
    TLCD1-IN-1
  • HY-138098
    Sartorypyrone B
    Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213). Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases.
    Sartorypyrone B
  • HY-N12529
    13,14-EDT
    13,14-EDT is a metabolite of oxylipids and adrenal acid that is formed through the cytochrome P450 (CYP) pathway.
    13,14-EDT
  • HY-10572R
    Efavirenz (Standard)
    Efavirenz (Standard) is the analytical standard of Efavirenz. This product is intended for research and analytical applications. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
    Efavirenz (Standard)
  • HY-B1337S2
    Choline-d6 chloride
    Choline-d6 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
    Choline-d<sub>6</sub> chloride
  • HY-W040268S
    1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d62
    1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d62 is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane.
    1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d<sub>62</sub>
  • HY-128737
    Methyl β-D-Galactopyranoside
    Methyl β-D-Galactopyranoside is an endogenous metabolite.
    Methyl β-D-Galactopyranoside
  • HY-Y1809S1
    1-Hydroxyoctadecane-d2
    1-Hydroxyoctadecane-d2 is the deuterium labeled 1-Hydroxyoctadecane. 1-Hydroxyoctadecane is an endogenous metabolite.
    1-Hydroxyoctadecane-d<sub>2</sub>
  • HY-N2362S5
    DL-Alanine-15N
    DL-Alanine-15N is the 15N labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver.
    DL-Alanine-<sup>15</sup>N
  • HY-113239S
    Hydroxycotinine-d3
    Hydroxycotinine-d3 is deuterium labeled Hydroxycotinine. Hydroxycotinine is the main nicotine metabolite detected in smokers urine.
    Hydroxycotinine-d<sub>3</sub>
  • HY-B1804S
    Tricaprilin-13C3
    Tricaprilin-13C3 (Trioctanoin-13C3) is a 13C-labeled Tricaprilin (HY-B1804). Tricaprilin is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT).
    Tricaprilin-<sup>13</sup>C<sub>3</sub>
  • HY-N1387R
    4-Methoxycinnamic acid (Standard)
    4-Methoxycinnamic acid (Standard) is the analytical standard of 4-Methoxycinnamic acid. This product is intended for research and analytical applications. 4-Methoxycinnamic acid is detected as natural phenylpropanoid in A. preissii.
    4-Methoxycinnamic acid (Standard)
  • HY-19602
    Cedefingol
    Cedefingol is an antitumor compound with α-glucosidase inhibitory activity. Cedefingol was identified together with other compounds in fermented dark tea samples. The biotransformation of cedefingol is related to enzymatic hydrolysis, hydrolysis and biosynthesis. Cedefingol exhibited different bioactivities in samples with different fermentation times. The antioxidant properties of cedefingol showed certain activity in the DPPH model.
    Cedefingol
  • HY-E70053
    alpha-1,3-Galactosyltransferase (GTB)
    alpha-1,3-Galactosyltransferase (GTB) (alpha 1,3GT) catalyzes the synthesis of the xenoantigen or α-galactose (α-Gal) epitope. alpha-1,3-Galactosyltransferase (GTB) transfers galactose from UDP-Gal to type 1 or type 2, αFuc1→2βGal-R (H)-terminating acceptors.
    alpha-1,3-Galactosyltransferase (GTB)
Cat. No. Product Name / Synonyms Application Reactivity