2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W740360
    Daidzein-3',5',8-d3
    Daidzein-3',5',8-d3 is the deuterium labeled Daidzein (HY-N0019). Daidzein is a soy isoflavone, which acts as a PPAR activator.
    Daidzein-3',5',8-d<sub>3</sub>
  • HY-N0486S7
    L-Leucine-1-13C,15N
    		≥98.0%
    L-Leucine-1-13C,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
    L-Leucine-1-<sup>13</sup>C,<sup>15</sup>N
  • HY-N0060S1
    Ferulic acid-13C3
    		98.3%
    Ferulic acid-13C3 is the 13C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
    Ferulic acid-<sup>13</sup>C<sub>3</sub>
  • HY-165110
    1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol
    1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol (1-Stearin-2-palmitin-3-olein) is a compound mentioned in the study of the triglyceride composition of bovine milk fat. It was analyzed and identified by multiple chromatographic techniques, and a total of 120 triglycerides were identified.
    1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol
  • HY-106102
    [Deglycinamide9, Arginine8]-Vasopressin
    [Deglycinamide9, Arginine8]-Vasopressin is a Vasopressin (HY-B1811) analog. [Deglycinamide9, Arginine8]-Vasopressin induces platelet aggregation. [Deglycinamide9, Arginine8]-Vasopressin has hemostatic effect.
    [Deglycinamide9, Arginine8]-Vasopressin
  • HY-N0229S14
    L-Alanine-15N,d4
    L-Alanine-15N,d4 is the deuterium and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-<sup>15</sup>N,d<sub>4</sub>
  • HY-N1750R
    3-(2,4-Dihydroxyphenyl)propanoic acid (Standard)
    Garenoxacin (Standard) is the analytical standard of Garenoxacin. This product is intended for research and analytical applications. Garenoxacin (BMS284756) is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms.
    3-(2,4-Dihydroxyphenyl)propanoic acid (Standard)
  • HY-Y0262A
    Oxalic acid diammonium monohydrate
    		≥98.0%
    Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent.
    Oxalic acid diammonium monohydrate
  • HY-W765245
    Rapamycin-13C,d3-1
    Rapamycin-13C,d3-1 (Sirolimus-13C,d3-1) is the deuterium labeled and 13C-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
    Rapamycin-<sup>13</sup>C,d<sub>3</sub>-1
  • HY-Y0966S5
    Glycine-1-13C,15N
    		99.5%
    Glycine-1-13C,15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
    Glycine-1-<sup>13</sup>C,<sup>15</sup>N
  • HY-W008794R
    Normetanephrine hydrochloride (Standard)
    Normetanephrine (hydrochloride) (Standard) is the analytical standard of Normetanephrine (hydrochloride). This product is intended for research and analytical applications. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE).
    Normetanephrine hydrochloride (Standard)
  • HY-W013061S9
    Propane-1,2,3-triyl tripalmitate-d6
    Propane-1,2,3-triyl tripalmitate-d6 is the deuterium labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
    Propane-1,2,3-triyl tripalmitate-d<sub>6</sub>
  • HY-126370
    Geranylgeranyl pyrophosphate
    Geranylgeranyl pyrophosphate is a metabolite involved in protein geranylgeranylation. Geranylgeranyl pyrophosphate is the common precursor of  diterpenoids, for example, Paclitaxel. Geranylgeranyl pyrophosphate can be used for cancer research.
    Geranylgeranyl pyrophosphate
  • HY-W040821R
    DL-Homocysteine (Standard)
    Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents.
    DL-Homocysteine (Standard)
  • HY-115851
    Demethyl PL265
    Demethyl PL265 is an enduring dual ENKephalinase inhibitor (DENKi) that holds promise for pain relief.
    Demethyl PL265
  • HY-78096
    O-Deshydroxyethyl bosentan
    O-Deshydroxyethyl bosentan is a metabolite of Bosentan (HY-A0013), which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors.
    O-Deshydroxyethyl bosentan
  • HY-W009081R
    Tricosanoic acid (Standard)
    Naringenin (Standard) is the analytical standard of Naringenin. This product is intended for research and analytical applications. Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
    Tricosanoic acid (Standard)
  • HY-16686R
    α-Tocopherol phosphate (Standard)
    α-Tocopherol (phosphate) (Standard) is the analytical standard of α-Tocopherol (phosphate). This product is intended for research and analytical applications. α-Tocopherol phosphate is a compound with the high activity of vitamin E.
    α-Tocopherol phosphate (Standard)
  • HY-113049A
    Phosphoenolpyruvic acid trisodium
    Phosphoenolpyruvic acid (Phosphoenolpyruvate) trisodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid trisodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid trisodium also exhibits cytoprotective and anti-oxidative properties.
    Phosphoenolpyruvic acid trisodium
  • HY-W009216S2
    2'-Deoxycytidine-5'-monophosphate-15N3,d12 dilithium
    2'-Deoxycytidine-5'-monophosphoric acid-15N3,d12 dilithium is deuterium and 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
    2'-Deoxycytidine-5'-monophosphate-<sup>15</sup>N<sub>3</sub>,d<sub>12</sub> dilithium
Cat. No. Product Name / Synonyms Application Reactivity