2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-167688
    GSK-1562590
    GSK-1562590 is a uropeptide-II receptor antagonist with high affinity and selectivity. GSK-1562590 exhibits significant antagonistic activity in multiple bioassays and, in contrast, displays relatively sustained receptor binding times. GSK-1562590 can inhibit human urinary peptide-II-induced aortic contraction in rats in experiments, and its effect can last for at least 24 hours.
    GSK-1562590
  • HY-113008S1
    Urocanic acid-13C3
    Urocanic acid-13C3 is the 13C labeled Urocanic acid. Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR).
    Urocanic acid-<sup>13</sup>C<sub>3</sub>
  • HY-B0389S3
    D-Glucose-d1-1
    D-Glucose-d-11 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.
    D-Glucose-d<sub>1</sub>-1
  • HY-126716
    Leukotriene C4 methyl ester
    Leukotriene C4 methyl ester is a methyl ester of leukotriene C4. Leukotriene C4 methyl ester can be used for the research of psoriasis.
    Leukotriene C4 methyl ester
  • HY-76847S1
    Chenodeoxycholic Acid-d9
    Chenodeoxycholic Acid-d9 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Chenodeoxycholic Acid-d<sub>9</sub>
  • HY-117081
    C30(ω-hydroxy) Ceramide (d18:1/30:0)
    C30(ω-hydroxy) Ceramide (d18:1/30:0), a sphingolipid, is an epidermis-specifically vital component of the water barrier in mammalian skin. C30(ω-hydroxy) Ceramide (d18:1/30:0) is expressed in epidermal keratinocytes and male germ cells during their differentiation and maturation. C30(ω-hydroxy) Ceramide (d18:1/30:0) deficiency in the epiderm of Elovl4 deletion or mutation mice.
    C30(ω-hydroxy) Ceramide (d18:1/30:0)
  • HY-113354R
    Anserine (Standard)
    Anserine (Standard) is the analytical standard of Anserine. This product is intended for research and analytical applications. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].
    Anserine (Standard)
  • HY-156497
    Biotin-PEG8-Me-Tet
    Biotin-PEG8-Me-Tet is a biotin labeling.
    Biotin-PEG8-Me-Tet
  • HY-N10192
    Aculene D
    Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations.
    Aculene D
  • HY-N12650
    Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside
    Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside (compound 42) is a flavonol that can be isolated from Platanus Occidentalis. Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside is an inhibitor of alpha-amylase and DPP IV.
    Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside
  • HY-W015213S
    Adenine monohydrochloride hemihydrate-15N5
    Adenine monohydrochloride hemihydrate-15N5 is the 15N labeled Adenine monohydrochloride hemihydrate (HY-W015213). Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
    Adenine monohydrochloride hemihydrate-<sup>15</sup>N<sub>5</sub>
  • HY-N0415R
    Trigonelline chloride (Standard)
    Trigonelline (chloride) (Standard) is the analytical standard of Trigonelline (chloride). This product is intended for research and analytical applications. Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. Trigonelline chloride also has anti-HSV-1, antibacterial, and antifungal activity, and induces ferroptosis.
    Trigonelline chloride (Standard)
  • HY-165094
    1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol
    1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol (1-Myristin-2-linolein-3-palmitin) is a triglyceride with specific structural and distribution characteristics identified by specific analytical methods in human milk, infant formula, other mammalian milk, and vegetable oils.
    1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol
  • HY-B1449S2
    Uridine-13C-1
    Uridine-13C-1 is the 13C labeled Uridine.
    Uridine-<sup>13</sup>C-1
  • HY-111238
    Butyrolactone II
    Butyrolactone II is a fungal metabolite isolated from Aspergillus flavipes.
    Butyrolactone II
  • HY-W010589S1
    H-Abu-OH-d2
    H-Abu-OH-d2 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
    H-Abu-OH-d<sub>2</sub>
  • HY-N7175
    5,8-Epidioxyergosta-6,9(11),22-trien-3-ol
    5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis.
    5,8-Epidioxyergosta-6,9(11),22-trien-3-ol
  • HY-B0158S4
    Cytidine-d
    Cytidine-d is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catechol
    Cytidine-d
  • HY-120989
    Methyl 7(Z)-hexadecenoate
    Methyl 7(Z)-hexadecenoate is a sex pheromone produced by Trogoderma glabrum. Methyl 7(Z)-hexadecenoate can elicit attractive and sexually excitatory responses in Trogoderma glabrum males.
    Methyl 7(Z)-hexadecenoate
  • HY-145525
    Linoleoyl-L-carnitine chloride
    Linoleoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Hepatic levels of linoleoyl-L-carnitine are increased following high-dose (200 mg/kg) administration of Isoniazid (Item No. 20378) in mice.
    Linoleoyl-L-carnitine chloride
Cat. No. Product Name / Synonyms Application Reactivity