2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W001132S3
    Indole-15N
    Indole-15N is the 15N labeled Indole. Indole is an endogenous metabolite.
    Indole-<sup>15</sup>N
  • HY-113114S2
    Tetrahydrocortisone-d5-1
    Tetrahydrocortisone-d5-1 is the deuterium labeled Tetrahydrocortisone (HY-113114). Tetrahydrocortisone is a stress-induced hormone. Tetrahydrocortisone is also a urinary metabolite of Cortisone derived from the reduction of Cortisone by 5-reductase.
    Tetrahydrocortisone-d<sub>5</sub>-1
  • HY-120893
    trans-4,5-Epoxy-(E)-2-decenal
    trans-4,5-Epoxy-(E)-2-decenal is an oxygenated α,β-unsaturated aldehyde found in mammalian blood that gives blood its characteristic metallic odor. It is used by predators to locate blood or prey.
    trans-4,5-Epoxy-(E)-2-decenal
  • HY-E70412
    Galactose 1-dehydrogenase, E.coli
    Galactose 1-dehydrogenase, E.coli is a dehydrogenase expressed in E. coli. Galactose 1-dehydrogenase, E.coli catalyzes the oxidation of L-arabinose and D-galactose using NADP+/NAD+ as cofactors. Galactose 1-dehydrogenase, E.coli can be used in diagnostic tests to determine total galactose content and can also serve as a biocatalyst for producing galacturonate.
    Galactose 1-dehydrogenase, E.coli
  • HY-108694R
    γ-Tocotrienol (Standard)
    γ-Tocotrienol (Standard) is the analytical standard of γ-Tocotrienol. This product is intended for research and analytical applications. γ-Tocotrienol is an active form of vitamin E. γ-tocotrienol reverses the multidrug resistance (MDR) of breast cancer cells through the signaling pathway of NF-κB and P-gp. γ-Tocotrienol is also a novel radioprotector agent, can mitigate bone marrow radiation damage during targeted radionuclide treatment.
    γ-Tocotrienol (Standard)
  • HY-N3248
    Momordicoside G
    Momordicoside G (Momordicacoside G) is an orally active cucurbitane-type triterpene glycoside. Momordicoside G selectively induces apoptosis of M1-like macrophages, without affecting M2-like macrophages. Momordicoside G reduces intracellular ROS levels and promotes autophagy. Momordicoside G also has anticancer activity, inhibiting the growth of cancer cell lines. Momordicoside G stimulates M2-associated lung injury repair and prevents inflammatory lung cancer injury.
    Momordicoside G
  • HY-113353R
    Nicotinuric acid (Standard)
    Nicotinuric acid (Standard) is the analytical standard of Nicotinuric acid. This product is intended for research and analytical applications. Nicotinuric acid is an acyl glycine. Nicotinuric acid is a metabolite of nicotinic acid.
    Nicotinuric acid (Standard)
  • HY-W771037
    2-Oxoarginine-13C6
    2-Oxoarginine-13C6 (δ-Guanido-α-ketovaleric Acid-13C6) is the 13C-labeled 2-Oxoarginine (HY-113417).
    2-Oxoarginine-<sup>13</sup>C<sub>6</sub>
  • HY-N11429
    Glycochenodeoxycholic acid 3-glucuronide
    Glycochenodeoxycholic acid 3-glucuronide is a type of steroid glucuronide and a plasma metabolite that can be used in the research of biomarkers for diabetes and hepatocellular carcinoma (HCC).
    Glycochenodeoxycholic acid 3-glucuronide
  • HY-W008841S3
    N-Methylformamide-d1
    N-Methylformamide-d1 is the deuterium labeled N-Methylformamide.
    N-Methylformamide-d<sub>1</sub>
  • HY-W008841S2
    N-Methylformamide-d4
    N-Methylformamide-d4 is the deuterium labeled N-Methylformamide.
    N-Methylformamide-d<sub>4</sub>
  • HY-165038
    1,2-Didecanoyl-3-stearoyl-rac-glycerol
    1,2-Didecanoyl-3-stearoyl-rac-glycerol (1,2-Caprin-3-stearin) is a triglyceride.
    1,2-Didecanoyl-3-stearoyl-rac-glycerol
  • HY-N0092S1
    Inosine-13C
    Inosine-13C is the 13C labeled Inosine. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors.
    Inosine-<sup>13</sup>C
  • HY-142088
    Beauverolide Ka
    Beauverolide Ka, a cyclotetradepsipeptide, is a metabolite of Beauveria bassiana fungus. Beauverolide Ka stimulates glucose uptake in cultured rat L6 myoblasts at 50 μM. Beauverolide Ka exhibits protecting effects on HEI-OC1 cells at 10 μM and shows dose-dependent activity in both L6 myoblasts and myotubes.
    Beauverolide Ka
  • HY-128748S1
    DL-Glyceraldehyde-2-13C
    DL-Glyceraldehyde-2-13C is the 13C labeled DL-Glyceraldehyde[1].
    DL-Glyceraldehyde-2-<sup>13</sup>C
  • HY-133707R
    β-Muricholic acid (Standard)
    Deracoxib (Standard) is the analytical standard of Deracoxib. This product is intended for research and analytical applications. 0
    β-Muricholic acid (Standard)
  • HY-W012860S1
    p-Tolualdehyde-d4
    p-Tolualdehyde-d4 is the deuterium labeled p-Tolualdehyde. p-Tolualdehyde is an endogenous metabolite.
    p-Tolualdehyde-d<sub>4</sub>
  • HY-W016733
    D-Citrulline
    		≥98.0%
    D-Citrulline (H-D-Cit-OH) is a stereoisomer of L-citrulline (HY-N0391). D-Citrulline significantly attenuates polymorphonuclear leukocyte (PMN)-induced cardiac contractile dysfunction in the isolated perfused rat heart subjected to ischemia/reperfusion via a non-NO-mediated mechanism.
    D-Citrulline
  • HY-B1331S
    Cyromazine-d4
    		≥99.0%
    Cyromazine-d4 is the deuterium labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
    Cyromazine-d<sub>4</sub>
  • HY-E70410
    NAD Synthetase
    NAD synthetase is responsible for the final step in the synthesis of nicotinamide adenine dinucleotide (NAD). The Km values for NAD, ATP, and ammonia of NAD synthetase from Escherichia coli are 200 μM, 11 μM, and 0.65 μM, respectively, while the Km values for NAD, ATP, and ammonia of NAD synthetase from yeast are 170 μM, 190 μM, and 64 μM, respectively. NAD synthetase can be used for enzymatic assays to determine ATP, ammonia, urea, or creatinine, and is also suitable for enzymatic cycling methods. Additionally, NAD synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative diseases.
    NAD Synthetase
Cat. No. Product Name / Synonyms Application Reactivity