2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W013061S10
    Propane-1,2,3-triyl tripalmitate-13C
    Propane-1,2,3-triyl tripalmitate-13C is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
    Propane-1,2,3-triyl tripalmitate-<sup>13</sup>C
  • HY-Y1373R
    Cyclohexanecarboxylic acid (Standard)
    Cyclohexanecarboxylic acid (Standard) is the analytical standard of Cyclohexanecarboxylic acid. This product is intended for research and analytical applications. Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action.
    Cyclohexanecarboxylic acid (Standard)
  • HY-W179801
    1,3-Diphenethylurea
    		≥98.0%
    1,3-Diphenethylurea is a compound derived from marine sources, exhibiting anti-cancer activity. 1,3-Diphenethylurea has been shown to potentially inhibit tumor growth. 1,3-Diphenethylurea contributes to the development of novel therapeutic strategies in fighting cancer.
    1,3-Diphenethylurea
  • HY-126230
    PAT-494
    PAT-494 is an ATX inhibitor with significant activity in biochemical and plasma assays. PAT-494 can reduce LPA levels in rat plasma through oral administration. The structure-activity relationship study of PAT-494 shows that its binding mode with ATX is novel and it can effectively occupy the hydrophobic pockets and channels of ATX.
    PAT-494
  • HY-118576
    Histidylprolineamide
    Histidylprolineamide (His-pro-amide) is a reactive amide, an intermediate in the histidine metabolic pathway.
    Histidylprolineamide
  • HY-100582S3
    Ribitol-5-13C
    Ribitol-5-13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol
    Ribitol-5-<sup>13</sup>C
  • HY-Y1809R
    1-Hydroxyoctadecane (Standard)
    1-Hydroxyoctadecane (Standard) is the analytical standard of 1-Hydroxyoctadecane. This product is intended for research and analytical applications. 1-Hydroxyoctadecane is an endogenous metabolite.
    1-Hydroxyoctadecane (Standard)
  • HY-W719128
    Propane-1,1,2-d3-1,2-diol
    Propane-1,1,2-d3-1,2-diol is the deuterium labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish.
    Propane-1,1,2-d<sub>3</sub>-1,2-diol
  • HY-N0593B
    Deoxycholic acid sodium hydrate
    Deoxycholic acid (cholanoic acid) sodium hydrate, a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5.
    Deoxycholic acid sodium hydrate
  • HY-N7092S20
    D(-​)​-​Fructose-18O-1
    D(-​)​-​Fructose-18O-1 is the 18O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
    D(-​)​-​Fructose-<sup>18</sup>O-1
  • HY-N0473S13
    L-Tyrosine-d2-2
    L-Tyrosine-d2-2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
    L-Tyrosine-d<sub>2</sub>-2
  • HY-E70297
    N-Acetylglucosaminyltransferase IVa
    N-Acetylglucosaminyltransferase IVa (MGAT4A) is a glycosyltransferase that can enhance the migration, invasion, and adhesion abilities of cancer cells, and increase β1,4GlcNAc branched glycans on integrin β1 (ITGB1), a tumor-associated glycoprotein closely related to cell motility.
    N-Acetylglucosaminyltransferase IVa
  • HY-W017443S4
    L-Asparagine-1,2,3,4-13C4 monohydrate
    L-Asparagine-1,2,3,4-13C4 monohydrate is the 13C labeled labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine-1,2,3,4-<sup>13</sup>C<sub>4</sub> monohydrate
  • HY-B0539S4
    Desloratadine-d4 hydrobromide
    Desloratadine-d4 hydrobromide is deuterated labeled Desloratadine (HY-B0539). Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities.
    Desloratadine-d<sub>4</sub> hydrobromide
  • HY-N0576R
    Solanesol (Standard)
    Solanesol (Standard) is the analytical standard of Solanesol (HY-N0576). This product is intended for research and analytical applications. Solanesol is an orally active aliphatic terpene alcohol. Solanesol is mainly found in tobacco and other Solanaceae plants. Solanesol induces HO-1 and Hsp70 expression, activates p38 and Akt signaling pathways, and inhibits Apoptosis (reduces caspase-3 and PARP cleavage). Solanesol has antioxidant, anti-inflammatory, and neuroprotective activities. Solanesol can be used in the research of Huntington's disease, alcoholic liver disease, chronic inflammatory pain, anxiety, Alzheimer's disease, and bipolar disorder.
    Solanesol (Standard)
  • HY-W748594
    Apigenin triacetate
    Apigenin triacetate is a metabolite of F. graminearum. Apigenin triacetate can be downregulated in F. graminearum by chitosan treatment. Apigenin triacetate derives from apigenin.
    Apigenin triacetate
  • HY-P2039
    Retrobradykinin
    Retrobradykinin has the reverse sequence of Bradykinin (HY-P0206). Retrobradykinin exhibits no kinin activity and can be used as a negative control for Bradykinin.
    Retrobradykinin
  • HY-115387
    Oleoyl proline
    Oleoyl proline is a novel N-acyl amine compound.
    Oleoyl proline
  • HY-W250315
    Polypectate sodium
    Polypectate sodium is a major component of cell wall polysaccharides (pectins) and is used as a carbon source and inducer of polygalacturonase. Polypectate sodium can also be used to evaluate alkaline active and alkaline stable pectate lyases from Streptomyces spp. and to study the optimization of polygalacturonase production from Xanthophyllum spp. and reaction conditions.
    Polypectate sodium
  • HY-Y0488AR
    Formic acid ammonium (Standard)
    Formic acid (ammonium) (Standard) is the analytical standard of Formic acid (ammonium). This product is intended for research and analytical applications. Formic acid ammonium salt is an endogenous metabolite.
    Formic acid ammonium (Standard)
Cat. No. Product Name / Synonyms Application Reactivity